Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway. (Q36579769)

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5 January 2020

title

Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway (English)

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5 January 2020

6

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5 January 2020

author name string

Vijay Koka

1

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5 January 2020

Xiao Ru Huang

2

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5 January 2020

Arthur C K Chung

3

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5 January 2020

Wansheng Wang

4

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5 January 2020

Luan D Truong

5

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5 January 2020

language of work or name

English

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publication date

10 April 2008

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The American Journal of Pathology

5 January 2020

published in

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5 January 2020

volume

172

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5 January 2020

page(s)

1174-1183

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5 January 2020

issue

5

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The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease.

5 January 2020

cites work

1 reference

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Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury

9 September 2017

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9 September 2017

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Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis

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Advanced glycation end products activate a chymase-dependent angiotensin II-generating pathway in diabetic complications

9 September 2017

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9 September 2017

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Blockade of the renin-angiotensin-aldosterone system: a key therapeutic strategy to reduce renal and cardiovascular events in patients with diabetes

9 September 2017

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AT1 receptor mediated augmentation of intrarenal angiotensinogen in angiotensin II-dependent hypertension

9 September 2017

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Vascular chymase: pathophysiological role and therapeutic potential of inhibition

9 September 2017

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Nephron number in patients with primary hypertension

9 September 2017

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Angiotensin-converting enzyme 2 is an essential regulator of heart function

9 September 2017

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A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9

9 September 2017

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The renin-angiotensin-aldosterone system: a specific target for hypertension management

9 September 2017

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Increased angiotensin-I converting enzyme gene expression in the failing human heart. Quantification by competitive RNA polymerase chain reaction

9 September 2017

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Kidneys and fluids in pressure regulation. Small volume but large pressure changes

9 September 2017

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Congenital oligonephropathy and the etiology of adult hypertension and progressive renal injury

9 September 2017

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Salt sensitivity in hypertension. Renal and cardiovascular implications

30 September 2017

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ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice.

28 June 2018

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Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II.

20 September 2018

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20 September 2018

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20 September 2018

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Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes

20 September 2018

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Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats.

20 September 2018

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20 September 2018

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Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats

20 September 2018

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20 September 2018

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Chymase is upregulated in diabetic nephropathy: implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease

20 September 2018

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12 December 2020

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12 December 2020

Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system

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12 December 2020

Activation of glomerular mitogen-activated protein kinases in angiotensin II-mediated hypertension

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12 December 2020

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12 December 2020

Does the angiotensin-converting enzyme (ACE)/ACE2 balance contribute to the fate of angiotensin peptides in programmed hypertension?

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12 December 2020

10.2353/AJPATH.2008.070762

Identifiers

DOI

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