Flavonoids attenuate cardiovascular disease, inhibit phosphodiesterase, and modulate lipid homeostasis in adipose tissue and liver (Q36583262)

15 August 2017

1 reference

title

Flavonoids attenuate cardiovascular disease, inhibit phosphodiesterase, and modulate lipid homeostasis in adipose tissue and liver (English)

1 reference

15 August 2017

cardiovascular disease

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Michael R Peluso

1

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15 August 2017

1 September 2006

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Experimental Biology and Medicine

15 August 2017

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15 August 2017

231

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15 August 2017

8

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15 August 2017

1287-1299

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Advances in flavonoid research since 1992.

15 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Dietary flavonoids: bioavailability, metabolic effects, and safety

21 January 2018

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https://api.crossref.org/works/10.1177%2F153537020623100802

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

21 January 2018

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https://api.crossref.org/works/10.1177%2F153537020623100802

Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis

21 January 2018

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https://api.crossref.org/works/10.1177%2F153537020623100802

General atomic and molecular electronic structure system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Electrostatics of nanosystems: application to microtubules and the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Fruit and vegetables, and cardiovascular disease: a review.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153537020623100802

Phytochemicals and cardiovascular disease. A statement for healthcare professionals from the American Heart Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Flavonoid intake and coronary mortality in Finland: a cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Atherosclerosis. the road ahead

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Effect of soybean phytoestrogen intake on low density lipoprotein oxidation resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Probing the binding of the flavonoid, quercetin to human serum albumin by circular dichroism, electronic absorption spectroscopy and molecular modelling methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Platelets in atherothrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Flavonoids inhibit platelet function through binding to the thromboxane A2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Modification of platelet function and arachidonic acid metabolism by bioflavonoids. Structure-activity relations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Quercetin inhibits collagen-stimulated platelet activation through inhibition of multiple components of the glycoprotein VI signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Isoflavones: their effects on cardiovascular risk and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Isoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Effect of genistein on endothelial function in postmenopausal women: a randomized, double-blind, controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Implication of cyclic nucleotide phosphodiesterase inhibition in the vasorelaxant activity of the citrus-fruits flavonoid (+/-)-naringenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Genistein activates the 3',5'-cyclic adenosine monophosphate signaling pathway in vascular endothelial cells and protects endothelial barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

The effect of the phytoestrogen genistein on plasma nitric oxide concentrations, endothelin-1 levels and endothelium dependent vasodilation in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Endothelium-dependent relaxation of rat aorta by butein, a novel cyclic AMP-specific phosphodiesterase inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Vasodilatation produced by orientin and its mechanism study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Epicatechin protects endothelial cells against oxidized LDL and maintains NO synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Genistein acutely stimulates nitric oxide synthesis in vascular endothelial cells by a cyclic adenosine 5'-monophosphate-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Soy protein with isoflavones, but not an isoflavone-rich supplement, improves arterial low-density lipoprotein metabolism and atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Comparison of regulative functions between dietary soy isoflavones aglycone and glucoside on lipid metabolism in rats fed cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Effects of soybean isoflavones, probiotics, and their interactions on lipid metabolism and endocrine system in an animal model of obesity and diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Modulation of carbohydrate metabolism and peptide hormones by soybean isoflavones and probiotics in obesity and diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Soy protein influences the development of the metabolic syndrome in male obese ZDFxSHHF rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Myricetin, quercetin and catechin-gallate inhibit glucose uptake in isolated rat adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Genistein inhibits insulin-stimulated glucose transport and decreases immunocytochemical labeling of GLUT4 carboxyl-terminus without affecting translocation of GLUT4 in isolated rat adipocytes: additional evidence of GLUT4 activation by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Genistein is a natural inhibitor of hexose and dehydroascorbic acid transport through the glucose transporter, GLUT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and Glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Effects of phytochemicals of Flemingia vestita (Fabaceae) on glucose 6-phosphate dehydrogenase and enzymes of gluconeogenesis in a cestode (Raillietina echinobothrida).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Obesity, Metabolic Syndrome, and Cardiovascular Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Obesity: the new worldwide epidemic threat to general health and our complete lack of effective treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Structure, localization, and regulation of cGMP-inhibited phosphodiesterase (PDE3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

The role of cyclic nucleotide phosphodiesterases in the regulation of adipocyte lipolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Lipase-selective functional domains of perilipin A differentially regulate constitutive and protein kinase A-stimulated lipolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Antilipolytic action of insulin: role of cAMP phosphodiesterase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

The soy isoflavone genistein decreases adipose deposition in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Genistein-induced changes in lipid metabolism of ovariectomized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Differential effects of flavonoids on 3T3-L1 adipogenesis and lipolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Effects of flavonoids on cyclic AMP phosphodiesterase and lipid mobilization in rat adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Genistein affects lipogenesis and lipolysis in isolated rat adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Intracellular mediators of procyanidin-induced lipolysis in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Milrinone, a selective phosphodiesterase 3 inhibitor, stimulates lipolysis, endogenous glucose production, and insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Isoflavones found in Korean soybean paste as 3-hydroxy-3-methylglutaryl Coenzyme A reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Hepatocyte apoB-containing lipoprotein secretion is decreased by the grapefruit flavonoid, naringenin, via inhibition of MTP-mediated microsomal triglyceride accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Inhibitory activity of diacylglycerol acyltransferase (DGAT) and microsomal triglyceride transfer protein (MTP) by the flavonoid, taxifolin, in HepG2 cells: potential role in the regulation of apolipoprotein B secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Modulation of cyclic AMP levels in a clonal neural cell line by inhibitors of tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Tyrosine kinase-independent inhibition of cyclic-AMP phosphodiesterase by genistein and tyrphostin 51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

The tyrosine kinase inhibitor genistein increases basal cAMP and potentiates forskolin-induced cAMP accumulation in A549 human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Effect of genistein on both basal and glucagon-induced levels of cAMP in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Hepatic steatosis: a mediator of the metabolic syndrome. Lessons from animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Heterologous expression, purification, and characterization of human triacylglycerol hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Triacylglycerol hydrolase: role in intracellular lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Activation of rat liver cholesterol ester hydrolase by cAMP-dependent protein kinase and protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Insulin, glucagon and fatty acid treatment of hepatocytes does not result in phosphorylation or changes in activity of triacylglycerol hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Activation of the lipid droplet controls the rate of lipolysis of triglycerides in the insect fat body

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Characterization of CCAAT/enhancer-binding protein alpha as a cyclic AMP-responsive nuclear regulator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

C/EBPalpha activates the transcription of triacylglycerol hydrolase in 3T3-L1 adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Intracellular triacylglycerol lipase: its role in the assembly of hepatic very-low-density lipoprotein (VLDL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

The physiological role of triacylglycerol hydrolase in lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Genistein enhances expression of genes involved in fatty acid catabolism through activation of PPARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Molecular mechanisms of action of the soy isoflavones includes activation of promiscuous nuclear receptors. A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Regulation of triacylglycerol hydrolase expression by dietary fatty acids and peroxisomal proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Asparagine and glutamine: using hydrogen atom contacts in the choice of side-chain amide orientation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Taking geometry to its edge: fast unbound rigid (and hinge-bent) docking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Automated analysis of interatomic contacts in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Posttranslational processing of SREBP-1 in rat hepatocytes is regulated by insulin and cAMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

The coactivator PGC-1 is involved in the regulation of the liver carnitine palmitoyltransferase I gene expression by cAMP in combination with HNF4 alpha and cAMP-response element-binding protein (CREB)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

A tripartite array of transcription factor binding sites mediates cAMP induction of phosphoenolpyruvate carboxykinase gene transcription and its inhibition by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

Flavonoid Intake and Long-term Risk of Coronary Heart Disease and Cancer in the Seven Countries Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020623100802

10.1177/153537020623100802

21 January 2018

Identifiers

DOI

1 reference

release_ipqtgtkrnbcyvo2ikss7vvswrq

15 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ipqtgtkrnbcyvo2ikss7vvswrq

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

16946397

1 reference

PubMed ID

16946397