Fucoxanthin enhances cisplatin-induced cytotoxicity via NFκB-mediated pathway and downregulates DNA repair gene expression in human hepatoma HepG2 cells (Q36586981)

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scientific article published on 8 January 2013

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English	Fucoxanthin enhances cisplatin-induced cytotoxicity via NFκB-mediated pathway and downregulates DNA repair gene expression in human hepatoma HepG2 cells	scientific article published on 8 January 2013

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Fucoxanthin enhances cisplatin-induced cytotoxicity via NFκB-mediated pathway and downregulates DNA repair gene expression in human hepatoma HepG2 cells (English)

1 reference

Europe PubMed Central

15 August 2017

hepatocellular carcinoma

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based on heuristic

inferred from title

author name string

Cheng-Ling Liu

1

1 reference

Europe PubMed Central

15 August 2017

Yun-Ping Lim

2

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Europe PubMed Central

15 August 2017

Miao-Lin Hu

3

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Europe PubMed Central

15 August 2017

publication date

8 January 2013

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Europe PubMed Central

15 August 2017

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Europe PubMed Central

15 August 2017

11

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Europe PubMed Central

15 August 2017

1

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Europe PubMed Central

15 August 2017

50-66

1 reference

Europe PubMed Central

15 August 2017

copyright license

Creative Commons Attribution 4.0 International

8 January 2013

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April 2022 Public Data File from Crossref

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Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174T cells

1 reference

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Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-κB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages

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1 reference

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Fucoxanthin enhances HO-1 and NQO1 expression in murine hepatic BNL CL.2 cells through activation of the Nrf2/ARE system partially by its pro-oxidant activity

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Identifiers

10.3390/MD11010050

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Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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