Epidermal sphingolipids: metabolism, function, and roles in skin disorders (Q36589543)

15 August 2017

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title

Epidermal sphingolipids: metabolism, function, and roles in skin disorders (English)

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15 August 2017

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Walter M Holleran

1

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15 August 2017

Yutaka Takagi

series ordinal

2

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15 August 2017

Yoshikazu Uchida

series ordinal

3

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15 August 2017

language of work or name

English

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publication date

1 September 2006

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15 August 2017

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15 August 2017

580

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15 August 2017

23

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15 August 2017

5456-5466

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Optimization of physiological lipid mixtures for barrier repair

15 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Molecular models of the intercellular lipid lamellae in mammalian stratum corneum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Lipid mixtures prepared with well-defined synthetic ceramides closely mimic the unique stratum corneum lipid phase behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Deficiency of epidermal protein-bound omega-hydroxyceramides in atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Mutations in lipid transporter ABCA12 in harlequin ichthyosis and functional recovery by corrective gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Coordinate assembly of lipids and enzyme proteins into epidermal lamellar bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Keratinocyte differentiation is induced by cell-permeant ceramides and its proliferation is promoted by sphingosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Ceramide signalling: regulatory role in cell proliferation, differentiation and apoptosis in human epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Induction of apoptosis by synthetic ceramide analogues in the human keratinocyte cell line HaCaT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Localization of epidermal sphingolipid synthesis and serine palmitoyl transferase activity: alterations imposed by permeability barrier requirements

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Identification of a family of animal sphingomyelin synthases

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Lamellar body-enriched fractions from neonatal mice: preparative techniques and partial characterization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Lipid composition and acid hydrolase content of lamellar granules of fetal rat epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Glucosylceramide accumulates preferentially in lamellar bodies in differentiated keratinocytes

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Induction of ceramide glucosyltransferase activity in cultured human keratinocytes. Correlation with culture differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Up-regulation of glucosylceramide synthase expression and activity during human keratinocyte differentiation

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Localization of ceramide and glucosylceramide in human epidermis by immunogold electron microscopy.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

New acylceramide in native and reconstructed epidermis

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Human epidermal glucosylceramides are major precursors of stratum corneum ceramides

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Lipid content and water permeability of skin and oral mucosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Functional consequences of a neutral pH in neonatal rat stratum corneum

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Processing of epidermal glucosylceramides is required for optimal mammalian cutaneous permeability barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Mice with type 2 and 3 Gaucher disease point mutations generated by a single insertion mutagenesis procedure

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Epidermal abnormalities may distinguish type 2 from type 1 and type 3 of Gaucher disease.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Sphingomyelinase in Pig and Human Epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Permeability barrier disorder in Niemann-Pick disease: sphingomyelin-ceramide processing required for normal barrier homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

The aged epidermal permeability barrier. Structural, functional, and lipid biochemical abnormalities in humans and a senescent murine model

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

The complex life of simple sphingolipids

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Omega-hydroxyceramides are required for corneocyte lipid envelope (CLE) formation and normal epidermal permeability barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Ceramides are bound to structural proteins of the human foreskin epidermal cornified cell envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

A novel function for transglutaminase 1: attachment of long-chain omega-hydroxyceramides to involucrin by ester bond formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Basis for the permeability barrier abnormality in lamellar ichthyosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Sphingolipid activator proteins are required for epidermal permeability barrier formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Accumulation of protein-bound epidermal glucosylceramides in beta-glucocerebrosidase deficient type 2 Gaucher mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Saposin A: second cerebrosidase activator protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Isolation, characterization, and proteolysis of human prosaposin, the precursor of saposins (sphingolipid activator proteins).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Impaired sphingomyelinase activity and epidermal differentiation in atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Identification and characterization of a novel ABCA subfamily member, ABCA12, located in the lamellar ichthyosis region on 2q34

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Mutations in the transporter ABCA12 are associated with lamellar ichthyosis type 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

The human ATP-binding cassette (ABC) transporter superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Abnormal Lamellar Granules in Harlequin Ichthyosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Ichthyosis: mechanisms of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

The permeability barrier in mammalian epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Ceramide and cholesterol composition of the skin of patients with atopic dermatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Stratum corneum lipid abnormalities in atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

High-expression of sphingomyelin deacylase is an important determinant of ceramide deficiency leading to barrier disruption in atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Sphingosylphosphorylcholine is upregulated in the stratum corneum of patients with atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Decreased levels of sphingosine, a natural antimicrobial agent, may be associated with vulnerability of the stratum corneum from patients with atopic dermatitis to colonization by Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Abnormal expression of sphingomyelin acylase in atopic dermatitis: an etiologic factor for ceramide deficiency?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Skin lipids and epidermal differentiation in atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Alterations of glucosylceramide-beta-glucosidase levels in the skin of patients with psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Lysosomal degradation on vesicular membrane surfaces. Enhanced glucosylceramide degradation by lysosomal anionic lipids and activators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Saposin D: a sphingomyelinase activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Interfacial regulation of acid ceramidase activity. Stimulation of ceramide degradation by lysosomal lipids and sphingolipid activator proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Content of the different lipid classes in psoriatic scale

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

Abnormality of Water Barrier Function in Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.039

10.1016/J.FEBSLET.2006.08.039

21 January 2018

Identifiers

DOI

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15 August 2017

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