Challenges and opportunities in dystrophin-deficient cardiomyopathy gene therapy. (Q36599311)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16987891%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

review article

1 reference

title

Challenges and opportunities in dystrophin-deficient cardiomyopathy gene therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16987891%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16987891%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Dongsheng Duan

series ordinal

1

1 reference

15 August 2017

language of work or name

1 reference

1 October 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16987891%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

published in

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16987891%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

15 Spec No 2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16987891%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

R253-61

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16987891%20AND%20SRC:MED&resulttype=core&format=json

C-terminal-truncated microdystrophin recruits dystrobrevin and syntrophin to the dystrophin-associated glycoprotein complex and reduces muscular dystrophy in symptomatic utrophin/dystrophin double-knockout mice

30 December 2019

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30 September 2017

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30 September 2017

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Disruption of the beta-sarcoglycan gene reveals pathogenetic complexity of limb-girdle muscular dystrophy type 2E

30 September 2017

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Disruption of the sarcoglycan-sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy

30 September 2017

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30 September 2017

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30 September 2017

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Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice

30 September 2017

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30 September 2017

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Transgenic mdx mice expressing dystrophin with a deletion in the actin-binding domain display a "mild Becker" phenotype

30 September 2017

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Forced expression of dystrophin deletion constructs reveals structure-function correlations.

30 September 2017

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Regulation of myosin heavy chain genes in the heart

30 September 2017

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Genotype/phenotype correlations in Duchenne/Becker dystrophy

30 September 2017

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Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Dp71 can restore the dystrophin-associated glycoprotein complex in muscle but fails to prevent dystrophy.

30 September 2017

1 reference

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Enteroviral protease 2A directly cleaves dystrophin and is inhibited by a dystrophin-based substrate analogue

30 September 2017

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The molecular basis of activity-induced muscle injury in Duchenne muscular dystrophy

28 June 2018

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28 June 2018

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Contractile properties of myocardium are altered in dystrophin-deficient mdx mice.

28 June 2018

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A mutation in the dystrophin gene selectively affecting dystrophin expression in the heart

28 June 2018

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28 June 2018

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28 June 2018

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20 September 2018

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20 September 2018

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20 September 2018

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Fast-twitch skeletal muscles of dystrophic mouse pups are resistant to injury from acute mechanical stress

20 September 2018

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Expression of Dp260 in muscle tethers the actin cytoskeleton to the dystrophin-glycoprotein complex and partially prevents dystrophy.

20 September 2018

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Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity

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20 September 2018

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20 September 2018

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20 September 2018

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Dystrophin-deficient cardiomyocytes are abnormally vulnerable to mechanical stress-induced contractile failure and injury

20 September 2018

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12 December 2020

Progression of dystrophic features and activation of mitogen-activated protein kinases and calcineurin by physical exercise, in hearts of mdx mice

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12 December 2020

Cardiomyopathy is independent of skeletal muscle disease in muscular dystrophy

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12 December 2020

Spectrin-like repeats from dystrophin and alpha-actinin-2 are not functionally interchangeable

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12 December 2020

Survival in Duchenne muscular dystrophy: improvements in life expectancy since 1967 and the impact of home nocturnal ventilation

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12 December 2020

Cardiac assessment in childhood carriers of Duchenne and Becker muscular dystrophies

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12 December 2020

Successful heart transplantation in patients with inherited myopathies associated with end-stage cardiomyopathy

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12 December 2020

Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy

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12 December 2020

Phenotype of dystrophinopathy in old mdx mice

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12 December 2020

Development of cardiomyopathy in female carriers of Duchenne and Becker muscular dystrophies

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12 December 2020

MyoD is required for myogenic stem cell function in adult skeletal muscle

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12 December 2020

A Point Mutation in the 5' Splice Site of the Dystrophin Gene First Intron Responsible for X-Linked Dilated Cardiomyopathy

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Cardiac dysfunction with Becker muscular dystrophy

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12 December 2020

Myocardial involvement is very frequent among patients affected with subclinical Becker's muscular dystrophy

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12 December 2020

Dystrophin is not a specific component of the cardiac costamere

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12 December 2020

Transgenic expression of green fluorescence protein can cause dilatedcardiomyopathy

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12 December 2020

Distinct patterns of dystrophin organization in myocyte sarcolemma and transverse tubules of normal and diseased human myocardium

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12 December 2020

Etiologies of cardiomyopathy and heart failure

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12 December 2020

Cardiac transplantation in a Duchenne muscular dystrophy carrier

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12 December 2020

Transgenic over-expression of a motor protein at high levels results in severe cardiac pathology

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12 December 2020

Cardiac involvement in carriers of Duchenne and Becker muscular dystrophy

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12 December 2020

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12 December 2020

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12 December 2020

Acute respiratory failure following intravenous verapamil in Duchenne's muscular dystrophy

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12 December 2020

The association of cardiac muscle necrosis and inflammation with the degenerative and persistent myopathy of MDX mice

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12 December 2020

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12 December 2020

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12 December 2020

The molecular basis of muscular dystrophy in the mdx mouse: a point mutation

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12 December 2020

Dystrophin-glycoprotein complex and laminin colocalize to the sarcolemma and transverse tubules of cardiac muscle

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12 December 2020

X-linked dilated cardiomyopathy. Molecular genetic evidence of linkage to the Duchenne muscular dystrophy (dystrophin) gene at the Xp21 locus

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12 December 2020

Utrophin localization in normal and dystrophin-deficient heart

1 reference

12 December 2020

Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice

1 reference

12 December 2020

Successful heart transplantation in Becker's muscular dystrophy

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12 December 2020

Treatment of the heart in Duchenne muscular dystrophy

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12 December 2020

Dissecting the signaling and mechanical functions of the dystrophin-glycoprotein complex

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12 December 2020

Cardiac abnormalities and skeletal muscle weakness in carriers of Duchenne and Becker muscular dystrophies and controls

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12 December 2020

Dystrophin-deficient myocardium is vulnerable to pressure overload in vivo

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12 December 2020

Identifiers

DOI

10.1093/HMG/DDL180

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16987891%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16987891%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference