Molecular biology of hepatitis B virus: effect of nucleotide substitutions on the clinical features of chronic hepatitis B. (Q36602673)

15 August 2017

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title

Molecular biology of hepatitis B virus: effect of nucleotide substitutions on the clinical features of chronic hepatitis B. (English)

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15 August 2017

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Osamu Yokosuka

1

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PubMed ID

16998621

15 August 2017

Makoto Arai

series ordinal

2

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15 August 2017

1 September 2006

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Medical Molecular Morphology

15 August 2017

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15 August 2017

39

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15 August 2017

3

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15 August 2017

113-120

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https://scigraph.springernature.com/pub.10.1007/s00795-006-0328-5

15 August 2017

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cites work

Different types of ground glass hepatocytes in chronic hepatitis B virus infection contain specific pre-S mutants that may induce endoplasmic reticulum stress

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https://api.crossref.org/works/10.1007%2FS00795-006-0328-5

Effects of a frequent double-nucleotide basal core promoter mutation and its putative single-nucleotide precursor mutations on hepatitis B virus gene expression and replication

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00795-006-0328-5

Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC).

21 January 2018

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12 December 2020

Hepatic purine and pyrimidine metabolism: implications for antiviral chemotherapy of viral hepatitis

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12 December 2020

Detection of mutations in the enhancer 2/core promoter region of hepatitis B virus in patients with chronic hepatitis B virus infection: comparison with mutations in precore and core regions in relation to clinical status

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12 December 2020

Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy.

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12 December 2020

The hepatitis B virus large surface protein (LHBs) is a transcriptional activator

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12 December 2020

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

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12 December 2020

Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes.

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12 December 2020

Hypermodification and immune escape of an internally deleted middle-envelope (M) protein of frequent and predominant hepatitis B virus variants

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12 December 2020

Visualization of a 4-helix bundle in the hepatitis B virus capsid by cryo-electron microscopy.

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12 December 2020

Liver-specific enhancer II is the target for the p53-mediated inhibition of hepatitis B viral gene expression

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12 December 2020

Differential regulation of hepatitis B virus gene expression by the Sp1 transcription factor

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12 December 2020

Precore mutations and core clustering mutations in chronic hepatitis B virus infection

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12 December 2020

Hepatitis B virus envelope variation after transplantation with and without hepatitis B immune globulin prophylaxis

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12 December 2020

Mutational analysis of the hepatitis B virus P gene product: domain structure and RNase H activity

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12 December 2020

Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Lamivudine Clinical Investigation Group

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12 December 2020

Variations in codons 84-101 in the core nucleotide sequence correlate with hepatocellular injury in chronic hepatitis B virus infection

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12 December 2020

HepG2 cell binding activities of different hepatitis b virus isolates: inhibitory effect of anti-HBs and anti-preS1(21–47)

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12 December 2020

Hepatitis B e antigen polypeptides isolated from sera of individuals infected with hepatitis B virus: comparison with HBeAg polypeptide derived from Dane particles

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12 December 2020

The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance

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12 December 2020

Molecular heterogeneity of e antigen polypeptides in sera from carriers of hepatitis B virus

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12 December 2020

Biological impact of natural COOH-terminal deletions of hepatitis B virus X protein in hepatocellular carcinoma tissues.

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12 December 2020

Hepatitis B virus genomes that cannot synthesize pre-S2 proteins occur frequently and as dominant virus populations in chronic carriers in Italy

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12 December 2020

Hepatitis B virus capsid: localization of the putative immunodominant loop (residues 78 to 83) on the capsid surface, and implications for the distinction between c and e-antigens.

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12 December 2020

Geographic distribution of hepatitis B virus (HBV) genotype in patients with chronic HBV infection in Japan

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12 December 2020

Regulation of transcription from the hepatitis B virus major surface antigen promoter by the Sp1 transcription factor

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12 December 2020

Assembly and antigenicity of hepatitis B virus core particles

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12 December 2020

Hepatitis B virus sequence changes evolving in liver transplant recipients with fulminant hepatitis

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12 December 2020

The conversion of hepatitis B core antigen synthesized in E coli into e antigen

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12 December 2020

Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication

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12 December 2020

Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes

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12 December 2020

Purification and characterization of a naturally processed hepatitis B virus peptide recognized by CD8+ cytotoxic T lymphocytes

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12 December 2020

Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivudine in vivo

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12 December 2020

Mechanism of suppression of hepatitis B virus precore RNA transcription by a frequent double mutation.

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12 December 2020

Two control elements in the hepatitis B virus S-promoter are important for full promoter activity mediated by CCAAT-binding factor

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12 December 2020

Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis.

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12 December 2020

Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region

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12 December 2020

The P gene product of hepatitis B virus is required as a structural component for genomic RNA encapsidation

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12 December 2020

Determination of the fold of the core protein of hepatitis B virus by electron cryomicroscopy

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12 December 2020

High affinity binding site for nuclear factor I next to the hepatitis B virus S gene promoter.

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12 December 2020

Core antigen mutations of human hepatitis B virus in hepatomas accumulate in MHC class II-restricted T cell epitopes

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12 December 2020

Emergence of YMDD motif mutants of hepatitis B virus during lamivudine treatment of immunocompetent type B hepatitis patients

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12 December 2020

Hepatitis B virus mutations in the pre-S genome before and after liver transplantation

1 reference

12 December 2020

Nucleotide sequence analysis of the precore region in patients with fulminant hepatitis B in the United States

1 reference

12 December 2020

Pre-S2 defective hepatitis B virus infection in patients with fulminant hepatitis.

1 reference

12 December 2020

Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

1 reference

12 December 2020

Is a function of the secreted hepatitis B e antigen to induce immunologic tolerance in utero?

1 reference

12 December 2020

Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against e antigen

1 reference

12 December 2020

Clinical implications of mutations C-to-T1653 and T-to-C/A/G1753 of hepatitis B virus genotype C genome in chronic liver disease

1 reference

12 December 2020

A cysteine and a hydrophobic sequence in the noncleaved portion of the pre-C leader peptide determine the biophysical properties of the secretory core protein (HBe protein) of human hepatitis B virus

1 reference

12 December 2020

ER-localization and functional expression of the HBV transactivator MHBst.

1 reference

12 December 2020

The mechanism of natural occurrence of two closely linked HBV precore predominant mutations

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12 December 2020

Hepadnaviral assembly is initiated by polymerase binding to the encapsidation signal in the viral RNA genome

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12 December 2020

Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen

1 reference

12 December 2020

Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation

1 reference

12 December 2020

Site-specific RNA binding by a hepatitis B virus reverse transcriptase initiates two distinct reactions: RNA packaging and DNA synthesis.

1 reference

12 December 2020

The hepatitis B virus and common mutants

1 reference

12 December 2020

The crystal structure of the human hepatitis B virus capsid

1 reference

12 December 2020

Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate

1 reference

12 December 2020

Posttranscriptional regulation of hepatitis B virus replication by the precore protein

1 reference

12 December 2020

Hepatitis B virus infection: precore mutants and its relation to viral genotypes and core mutations

1 reference

12 December 2020

Prevalence and significance of hepatitis B virus (HBV) pre-S mutants in serum and liver at different replicative stages of chronic HBV infection

1 reference

12 December 2020

Vaccine-induced escape mutant of hepatitis B virus

1 reference

12 December 2020

Regulation of hepatocyte nuclear factor 1 activity by wild-type and mutant hepatitis B virus X proteins

1 reference

12 December 2020

Infectious hepatitis B virus variant defective in pre-S2 protein expression in a chronic carrier.

1 reference

12 December 2020

Detection and direct sequencing of hepatitis B virus genome by DNA amplification method

1 reference

12 December 2020

Distribution of hepatitis B viral genotypes and mutations in the core promoter and precore regions in acute forms of liver disease in patients from Chiba, Japan

1 reference

12 December 2020

YMDD motif in hepatitis B virus DNA polymerase influences on replication and lamivudine resistance: A study by in vitro full-length viral DNA transfection

1 reference

12 December 2020

Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis

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12 December 2020

Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection.

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12 December 2020

10.1007/S00795-006-0328-5

Identifiers

DOI

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15 August 2017

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PubMed ID

16998621