Mechanisms of disease: oxidative stress and inflammation in the pathogenesis of hypertension (Q36604954)

15 August 2017

1 reference

title

Mechanisms of disease: oxidative stress and inflammation in the pathogenesis of hypertension (English)

1 reference

15 August 2017

Nosratola D Vaziri

1

1 reference

PubMed ID

17003837

15 August 2017

Bernardo Rodríguez-Iturbe

series ordinal

2

1 reference

15 August 2017

1 October 2006

1 reference

Nature Clinical Practice Nephrology

15 August 2017

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15 August 2017

2

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15 August 2017

582-593

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15 August 2017

10

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NAD(P)H oxidase: role in cardiovascular biology and disease

15 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Vascular NAD(P)H oxidases: specific features, expression, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Oxidative stress and nitric oxide deficiency in the kidney: a critical link to hypertension?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Oxidative stress as a regulator of gene expression in the vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Is the balance between nitric oxide and superoxide altered in spontaneously hypertensive rats with endothelial dysfunction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Enhanced NO inactivation and hypertension induced by a high-fat, refined-carbohydrate diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Normalization of blood pressure and renal vascular resistance in SHR with a membrane-permeable superoxide dismutase mimetic: role of nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Long-term antioxidant administration attenuates mineralocorticoid hypertension and renal inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Superoxide dismutase and oxidative stress in Dahl salt-sensitive and -resistant rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Effect of a high-salt diet on oxidant enzyme activity in skeletal muscle microcirculation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Role of angiotensin II and free radicals in blood pressure regulation in a rat model of renal hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Expression of NOX-I, gp91phox, p47phox and P67phox in the aorta segments above and below coarctation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Plasma hydrogen peroxide production in human essential hypertension: role of heredity, gender, and ethnicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

The gamma-subunit of ENaC is more important for channel surface expression than the beta-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Overload proteinuria is followed by salt-sensitive hypertension caused by renal infiltration of immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Immunosuppressive treatment protects against angiotensin II-induced renal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Mycophenolate mofetil prevents salt-sensitive hypertension resulting from angiotensin II exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Reduction of renal immune cell infiltration results in blood pressure control in genetically hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

Preactivated peripheral blood monocytes in patients with essential hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

ATVB in focus: redox mechanisms in blood vessels

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Antioxidant and redox regulation of cellular signaling: introduction

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Reactive oxygen species in the vasculature: molecular and cellular mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Expression and cellular localization of classic NADPH oxidase subunits in the spontaneously hypertensive rat kidney

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Novel NAD(P)H oxidases in the cardiovascular system

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Enhancement of T cell receptor signaling by a mild oxidative shift in the intracellular thiol pool

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Hydrogen peroxide as a potent activator of T lymphocyte functions

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Antioxidant and redox regulation of gene transcription

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Antioxidant-mediated inhibition of the heat shock response leads to apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Stress proteins in inflammation.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Angiotensin II activates nuclear transcription factor kappaB through AT(1) and AT(2) in vascular smooth muscle cells: molecular mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Vasoactive hormones and renal sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Upregulation of renin-angiotensin system during differentiation of monocytes to macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Oxidative stress, renal infiltration of immune cells, and salt-sensitive hypertension: all for one and one for all.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Role of Oxidative Stress in Endothelial Dysfunction and Enhanced Responses to Angiotensin II of Afferent Arterioles from Rabbits Infused with Angiotensin II

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Enhanced contractility of renal afferent arterioles from angiotensin-infused rabbits: roles of oxidative stress, thromboxane prostanoid receptors, and endothelium

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Renal renin-angiotensin system

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

The intrarenal renin-angiotensin system in hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Regulation of intrarenal angiotensin II in hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Why are angiotensin concentrations so high in the kidney?

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Hypertension in Page (cellophane-wrapped) kidney is due to interstitial nephritis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Salt Intake, Oxidative Stress, and Renal Expression of NADPH Oxidase and Superoxide Dismutase

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Negative feedback regulation of reactive oxygen species on AT1 receptor gene expression

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Endothelial nitric oxide synthase in vascular disease: from marvel to menace

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

ADMA and oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Glycyrrhetinic derivatives inhibit hyperpolarization in endothelial cells of guinea pig and rat arteries

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Oxidative stress increases endothelin-1 synthesis in human coronary artery smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Reactive oxygen species as mediators of calcium signaling by angiotensin II: implications in vascular physiology and pathophysiology

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Increased nitric oxide inactivation by reactive oxygen species in lead-induced hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Superoxide dismutase, catalase, glutathione peroxidase and NADPH oxidase in lead-induced hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Effect of diet and exercise intervention on blood pressure, insulin, oxidative stress, and nitric oxide availability

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Effects of diabetes, insulin and antioxidants on NO synthase abundance and NO interaction with reactive oxygen species

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Two-week administration of tempol attenuates both hypertension and renal excretion of 8-Iso prostaglandin f2alpha

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Effect of antioxidant therapy on blood pressure and NO synthase expression in hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Supplemention with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Melatonin reduces renal interstitial inflammation and improves hypertension in spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Antioxidant-rich diet relieves hypertension and reduces renal immune infiltration in spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Up-regulation of kidney NAD(P)H oxidase and calcineurin in SHR: reversal by lifelong antioxidant supplementation

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

The antioxidant tempol prevents and partially reverses dexamethasone-induced hypertension in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Role of increased oxygen free radical activity in the pathogenesis of uremic hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Enhanced nitric oxide inactivation and protein nitration by reactive oxygen species in renal insufficiency

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Oxidative stress and dysregulation of superoxide dismutase and NADPH oxidase in renal insufficiency

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: evidence for an involvement of protein kinase C

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Enhanced nitric oxide inactivation in aortic coarctation-induced hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Nitric oxide synthase expression in hypertension induced by inhibition of glutathione synthase

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Lead exposure raises superoxide and hydrogen peroxide in human endothelial and vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Oxidative stress in uremia: nature, mechanisms, and potential consequences

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

A high-fat, refined-carbohydrate diet induces endothelial dysfunction and oxidant/antioxidant imbalance and depresses NOS protein expression

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Oxidative stress and dysregulation of NAD(P)H oxidase and antioxidant enzymes in diet-induced metabolic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Effects of aortic coarctation on aortic antioxidant enzymes and NADPH oxidase protein expression

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Microvascular and tubulointerstitial injury associated with chronic hypoxia-induced hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Increased oxidative stress in rats with chronic nitric oxide depletion: measurement of urinary 8-hydroxy-2'-deoxyguanosine excretion

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Protective effects of the flavonoid quercetin in chronic nitric oxide deficient rats.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Pulsatile stretch stimulates superoxide production and activates nuclear factor-kappa B in human coronary smooth muscle

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Increased superoxide production in hypertensive patients with diabetes mellitus: role of nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Effect of a short-term diet and exercise intervention on oxidative stress, inflammation, MMP-9, and monocyte chemotactic activity in men with metabolic syndrome factors

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Evidence for peroxynitrite formation in the vasculature of women with preeclampsia

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Treatment of hypertension with ascorbic acid

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

NF-kappaB inhibition ameliorates angiotensin II-induced inflammatory damage in rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Lead-induced hypertension. III. Increased hydroxyl radical production

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Suppression of the development of hypertension by the inhibitor of inducible nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Chronic treatment with a superoxide dismutase mimetic prevents vascular remodeling and progression of hypertension in salt-loaded stroke-prone spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Mycophenolate mofetil prevents salt-sensitive hypertension resulting from nitric oxide synthesis inhibition

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Early and sustained inhibition of nuclear factor-kappaB prevents hypertension in spontaneously hypertensive rats.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Antioxidant treatment prevents renal damage and dysfunction and reduces arterial pressure in salt-sensitive hypertension.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Hypertension induced by aortic coarctation above the renal arteries is associated with immune cell infiltration of the kidneys.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Evolution of renal interstitial inflammation and NF-kappaB activation in spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

The clinical diagnosis of hypertensive nephrosclerosis--how reliable is it?

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Hyperuricemia in primary and renal hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Hypertension in cyclosporine-treated renal transplant recipients is sodium dependent

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Analgesic abuse and hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Polymorphonuclear integrins, membrane fluidity, and cytosolic Ca(2+) content after activation in essential hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

The inflammatory aspect of the microcirculation in hypertension: oxidative stress, leukocytes/endothelial interaction, apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Immune cell CD62L and CD11a expression in response to a psychological stressor in human hypertension

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Vitamin E can reduce blood pressure in mild hypertensives

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Effect of vitamin C on ambulatory blood pressure and plasma lipids in older persons

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Vitamin E supplementation and cardiovascular events in high-risk patients

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes?

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Effects of exercise and diet on chronic disease

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Molecular mechanisms of vascular adaptations to exercise. Physical activity as an effective antioxidant therapy?

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Anti-inflammatory effects of AT1 receptor blockade provide end-organ protection in stroke-prone rats independently from blood pressure fall

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0283

7 January 2021

Identifiers

DOI

10.1038/NCPNEPH0283

1 reference

15 August 2017

1 reference

PubMed ID

17003837