Pattern recognition and biomarker validation using quantitative 1H-NMR-based metabolomics (Q36607286)

15 August 2017

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title

Pattern recognition and biomarker validation using quantitative 1H-NMR-based metabolomics (English)

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15 August 2017

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Natalie J Serkova

1

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PubMed ID

17009906

15 August 2017

Claus U Niemann

series ordinal

2

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15 August 2017

1 September 2006

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Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

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Combination of 'omics' data to investigate the mechanism(s) of hydrazine-induced hepatotoxicity in rats and to identify potential biomarkers

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Characterization of the biochemical effects of 1-nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition.

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1H NMR analysis for metabolites in serum and urine from rats administrated chronically with La(NO3)3.

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Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity

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NMR spectroscopic studies on the late onset form of 3-methylglutaconic aciduria type I and other defects in leucine metabolism.

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beta-Ureidopropionase deficiency: a novel inborn error of metabolism discovered using NMR spectroscopy on urine

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Influence of donor pretreatment with N-acetylcysteine on ischemia/reperfusion injury in rat kidney grafts

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Ischemic preconditioning improves energy state and transplantation survival in obese Zucker rat livers

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H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants.

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Metabolomics: an emerging post-genomic tool for nutrition

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Metabolic profiling of livers and blood from obese Zucker rats

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A biochemical prognostic model of outcome in paracetamol-induced acute liver injury.

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An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy

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Metabonomic evaluation of idiosyncrasy-like liver injury in rats cotreated with ranitidine and lipopolysaccharide

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Biomarkers for toxicodynamic monitoring of immunosuppressants: NMR-based quantitative metabonomics of the blood

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Detection of epithelial ovarian cancer using 1H-NMR-based metabonomics

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High-resolution 1H nuclear magnetic resonance spectroscopy analysis of bile samples obtained from a patient after orthotopic liver transplantation: new perspectives.

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Metabolites from cerebrospinal fluid in aneurysmal subarachnoid haemorrhage correlate with vasospasm and clinical outcome: a pattern-recognition 1H NMR study

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Potential biological markers for cerebrovascular disease.

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Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients

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High-resolution (1)H NMR and magic angle spinning NMR spectroscopic investigation of the biochemical effects of 2-bromoethanamine in intact renal and hepatic tissue

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Non-destructive quantitation of spermine in human prostate tissue samples using HRMAS 1H NMR spectroscopy at 9.4 T.

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The comparison of plasma deproteinization methods for the detection of low-molecular-weight metabolites by (1)H nuclear magnetic resonance spectroscopy

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Metabonomic investigations into hydrazine toxicity in the rat.

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Intracellular transport mechanisms: a critique of diffusion theory.

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Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis

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Metabonomics: a platform for studying drug toxicity and gene function

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Comparison of the effects of cyclosporin a on the metabolism of perfused rat brain slices during normoxia and hypoxia

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Drug-related hepatotoxicity

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31P MRS of heart grafts provides metabolic markers of early dysfunction

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Phosphomonoester concentrations differ between chronic lymphocytic leukemia cells and normal human lymphocytes

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Metabolic differences between primary and recurrent human brain tumors: a 1H NMR spectroscopic investigation

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Pattern recognition analysis of 1H NMR spectra from perchloric acid extracts of human brain tumor biopsies.

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In vivo quantification of choline compounds in the breast with 1H MR spectroscopy.

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Specificity of choline metabolites for in vivo diagnosis of breast cancer using 1H MRS at 1.5 T.

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Nuclear Magnetic Resonance Spectroscopic and Principal Components Analysis Investigations into Biochemical Effects of Three Model Hepatotoxins

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21 January 2018

Identifiers

DOI

10.1586/14737159.6.5.717

1 reference

15 August 2017

1 reference

PubMed ID

17009906