In vitro assays and biomarkers for drug-induced phospholipidosis (Q36609748)

15 August 2017

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title

In vitro assays and biomarkers for drug-induced phospholipidosis (English)

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15 August 2017

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David K Monteith

1

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15 August 2017

Ryan E Morgan

series ordinal

2

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15 August 2017

Bartley Halstead

series ordinal

3

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15 August 2017

language of work or name

English

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publication date

1 October 2006

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Expert Opinion on Drug Metabolism & Toxicology

15 August 2017

published in

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15 August 2017

volume

2

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15 August 2017

issue

5

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15 August 2017

page(s)

687-696

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Cationic amphiphilic drug-induced phospholipidosis

15 August 2017

cites work

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Fluorescence studies on binding of amphiphilic drugs to isolated lamellar bodies: relevance to phospholipidosis

21 January 2018

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Fusion of storage lysosomes in experimental lipidosis and glycogenosis

21 January 2018

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A review of the biology and toxicologic implications of the induction of lysosomal lamellar bodies by drugs

21 January 2018

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Chloroquine treatment does not cause phospholipid storage by depleting rat liver lysosomes of acid phospholipase A.

21 January 2018

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Perspectives on intracellular storage and transport of cationic-lipophilic drugs

21 January 2018

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Drug-induced phospholipidosis: issues and future directions

21 January 2018

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Histochemical evidence for lysosomal storage of acid glycosaminoglycans in splenic cells of rats treated with tilorone

21 January 2018

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Drug-phospholipid interactions: role in aminoglycoside nephrotoxicity

21 January 2018

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A cell-based approach for the early assessment of the phospholipidogenic potential in pharmaceutical research and drug development.

21 January 2018

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Analysis of two matrix metalloproteinase inhibitors and their metabolites for induction of phospholipidosis in rat and human hepatocytes(1).

21 January 2018

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Nile Red binding to HepG2 cells: an improved assay for in vitro studies of hepatosteatosis

21 January 2018

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Tricyclic antidepressant-induced lipidosis in human peripheral monocytes in vitro, as well as in a monocyte-derived cell line, as monitored by spectrofluorimetry and flow cytometry after staining with Nile red.

21 January 2018

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A toxicogenomic approach to drug-induced phospholipidosis: analysis of its induction mechanism and establishment of a novel in vitro screening system

21 January 2018

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Rapid-gradient HPLC method for measuring drug interactions with immobilized artificial membrane: comparison with other lipophilicity measures.

21 January 2018

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Hyperactivity of cathepsin B and other lysosomal enzymes in fibroblasts exposed to azithromycin, a dicationic macrolide antibiotic with exceptional tissue accumulation

21 January 2018

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Tetracycline-induced steatosis in primary canine hepatocyte cultures

21 January 2018

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Effect of amiodarone on the phospholipid and lamellar body content of lymphoblasts in vitro and peripheral blood lymphocytes in vivo.

21 January 2018

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Establishment of an in vitro high-throughput screening assay for detecting phospholipidosis-inducing potential

21 January 2018

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Validation of an in vitro screen for phospholipidosis using a high-content biology platform

21 January 2018

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Synthesis and SAR of 5-amino- and 5-(aminomethyl)benzofuran histamine H3 receptor antagonists with improved potency

21 January 2018

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21 January 2018

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Mucopolysaccharidosis-like cellular alterations in chondrocytes of rats treated with tilorone.

21 January 2018

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Nile red staining of lysosomal phospholipid inclusions

21 January 2018

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A clinical flow cytometric biomarker strategy: validation of peripheral leukocyte phospholipidosis using Nile red.

21 January 2018

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Epididymal and systemic phospholipidosis in rats and dogs treated with the dopamine D3 selective antagonist PNU-177864.

21 January 2018

1 reference

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Phenylacetylglycine, a putative biomarker of phospholipidosis: its origins and relevance to phospholipid accumulation using amiodarone treated rats as a model

21 January 2018

1 reference

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NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.687

Characterisation of a potential biomarker of phospholipidosis from amiodarone-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.687

Detection ofin vivo biomarkers of phospholipidosis using NMR-based metabonomic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.687

21 January 2018

Identifiers

DOI

10.1517/17425255.2.5.687

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release_xqdnfn7hibb7lpkk4wwhs6fh4a

15 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xqdnfn7hibb7lpkk4wwhs6fh4a

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference