Mechanistic biomarkers for cytotoxic acute kidney injury (Q36609753)

15 August 2017

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title

Mechanistic biomarkers for cytotoxic acute kidney injury (English)

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15 August 2017

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1

Vishal S Vaidya

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15 August 2017

Joseph V Bonventre

2

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15 August 2017

language of work or name

English

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publication date

1 October 2006

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Expert Opinion on Drug Metabolism & Toxicology

15 August 2017

published in

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15 August 2017

volume

2

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15 August 2017

issue

5

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15 August 2017

page(s)

697-713

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Preoperative renal risk stratification.

15 August 2017

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The price of innovation: new estimates of drug development costs

21 January 2018

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Assessment of renal injury in vivo

21 January 2018

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Renal injury and repair following S-1, 2 dichlorovinyl-L-cysteine administration to mice

21 January 2018

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Identifying differences in mRNA expression by representational difference analysis of cDNA

21 January 2018

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Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury

21 January 2018

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Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration

21 January 2018

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Identification of putative gene based markers of renal toxicity

21 January 2018

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Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family

21 January 2018

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TIM-1 induces T cell activation and inhibits the development of peripheral tolerance

21 January 2018

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The TIM gene family regulates autoimmune and allergic diseases

21 January 2018

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Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum.

21 January 2018

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Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury

21 January 2018

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Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury.

21 January 2018

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Expression of the kidney injury molecule 1 in the rat cochlea and induction by cisplatin

21 January 2018

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Human kidney injury molecule-1 is a tissue and urinary tumor marker of renal cell carcinoma

21 January 2018

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Kidney injury molecule-1 expression in murine polycystic kidney disease.

21 January 2018

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Microarray analysis of a reversible model and an irreversible model of anti-Thy-1 nephritis.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Distinct transcriptional changes in donor kidneys upon brain death induction in rats: insights in the processes of brain death.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Tubular kidney injury molecule-1 in protein-overload nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Gene expression profiling of nephrotoxicity from the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether ("compound A") in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Investigation on urinary proteins and renal mRNA expression in canine renal papillary necrosis induced by nefiracetam

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Induction of the TRPM-2 gene in cells undergoing programmed death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

The SGP-2 gene is developmentally regulated in the mouse kidney and abnormally expressed in collecting duct cysts in polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Measurement of urinary clusterin as an index of nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Modulation of clusterin isoforms is associated with all-trans retinoic acid-induced proliferative arrest and apoptosis of intimal smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Clusterin as a biomarker in murine and human intestinal neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Clusterin is a secreted marker for a hypoxia-inducible factor-independent function of the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Modulation of different clusterin isoforms in human colon tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Neutrophil gelatinase-associated lipocalin is up-regulated in human epithelial cells by IL-1 beta, but not by TNF-alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Induction of NGAL synthesis in epithelial cells of human colorectal neoplasia and inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Neutrophil gelatinase-associated lipocalin: a novel early urinary biomarker for cisplatin nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Kidney NGAL is a novel early marker of acute injury following transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

The lipocalin protein family: structural and sequence overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

An iron delivery pathway mediated by a lipocalin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Neutrophil gelatinase-associated lipocalin in normal and neoplastic human tissues. Cell type-specific pattern of expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Identification of a neutrophil gelatinase-associated lipocalin mRNA in human pancreatic cancers using a modified signal sequence trap method

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

The matrix metalloproteinase-9/neutrophil gelatinase-associated lipocalin complex plays a role in breast tumor growth and is present in the urine of breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Cystatin C as a marker of GFR--history, indications, and future research

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Early detection of acute renal failure by serum cystatin C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Cystatin C in a rat model of end-stage renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Urinary cystatin C as a specific marker of tubular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Immunomodulatory properties of cystatins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Expression of cathepsin B and cystatin C in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

The use of cystatin C to inhibit epithelial-mesenchymal transition and morphological transformation stimulated by transforming growth factor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

The CCN family of genes: a brief history

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Early detection of cysteine rich protein 61 (CYR61, CCN1) in urine following renal ischemic reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Urinary interleukin-18 is a marker of human acute tubular necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Interleukin-18 (IL-18) and infectious diseases, with special emphasis on diseases induced by intracellular pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Cloning of a new cytokine that induces IFN-gamma production by T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Interferon-gamma-inducing factor, a novel cytokine, enhances Fas ligand-mediated cytotoxicity of murine T helper 1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Interferon-gamma-inducing factor gene transfection into Lewis lung carcinoma cells reduces tumorigenicity in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Evidence of IL-18 as a novel angiogenic mediator

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Expression, roles, receptors, and regulation of osteopontin in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Reduced urinary excretion of intact osteopontin in patients with IgA nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Altered wound healing in mice lacking a functional osteopontin gene (spp1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Cellular fatty acid-binding proteins: their function and physiological significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Fatty acid-binding proteins as plasma markers of tissue injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Evolution of the family of intracellular lipid binding proteins in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Two types of fatty acid-binding protein in human kidney. Isolation, characterization and localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

The metabolic significance of mammalian fatty-acid-binding proteins: abundant proteins in search of a function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Urinary fatty acid–binding protein as a new clinical marker of the progression of chronic renal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Urinary liver-type fatty acid binding protein as a useful biomarker in chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Urinary excretion of fatty acid-binding protein reflects stress overload on the proximal tubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Structural studies on human muscle fatty acid binding protein at 1.4 A resolution: binding interactions with three C18 fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Lipid-binding proteins in rat and human kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Progress in myocardial damage detection: new biochemical markers for clinicians

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Identification and proteomic profiling of exosomes in human urine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Urinary measurement of Na+/H+ exchanger isoform 3 (NHE3) protein as new marker of tubule injury in critically ill patients with ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Induction of Zf9 in the kidney following early ischemia/reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

A sensitive and high-throughput assay to detect low-abundance proteins in serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Multiplexed particle-based flow cytometric assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Elevation of CXCR3-binding chemokines in urine indicates acute renal-allograft dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Label-free detection of small-molecule-protein interactions by using nanowire nanosensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Multiplexed electrical detection of cancer markers with nanowire sensor arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Urinary enzymes as biomarkers of renal injury in experimental nephrotoxicity of immunosuppressive drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Glutathione S-transferase isoenzymes in human renal carcinoma demonstrated by immunohistochemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Overexpression of glutathione s-transferase alpha in clear cell renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Urinary enzyme evaluation of nephrotoxicity in the dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Diurnal variations of urinary enzyme excretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Acute gentamicin-induced hypercalciuria and hypermagnesiuria in the rat: dose-response relationship and role of renal tubular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Renal kallikrein excretion as a distal nephrotoxicity marker during cadmium exposure in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Chromium-induced early changes in renal function among ferrochromium-producing workers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Hepatic biotransformation of the new calcium-mimetic agent, RWJ-68025, in the rat and in man--API-MS/MS identification of metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Chronic combined exposure to cadmium and arsenic exacerbates nephrotoxicity, particularly in metallothionein-I/II null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Early proximal tubule injury in experimental aristolochic acid nephropathy: functional and histological studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Cadmium nephrotoxicity and evacuation from the body in a rat modeled subchronic intoxication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Exposure to hydrocarbons and renal disease: an experimental animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Urinary clusterin levels in the rat correlate with the severity of tubular damage and may help to differentiate between glomerular and tubular injuries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

The angiogenic factor CYR61 in breast cancer: molecular pathology and therapeutic perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Role of caspases on cell death, inflammation, and cell cycle in glycerol-induced acute renal failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

The role of osteopontin in breast cancer: clinical and experimental studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Urinary actin, interleukin-6, and interleukin-8 may predict sustained arf after ischemic injury in renal allografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

NHE3 and NHERF are targeted to the basolateral membrane in proximal tubules of colchicine-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Magnesium depletion enhances cisplatin-induced nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Intrarenal distribution of clusterin following reduction of renal mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Rat model of perchloroethylene-induced renal dysfunctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

Proteomic-Based Identification of Cleaved Urinary beta2-microglobulin as a Potential Marker for Acute Tubular Injury in Renal Allografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.5.697

21 January 2018

Identifiers

DOI

10.1517/17425255.2.5.697

1 reference

15 August 2017

1 reference