Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). (Q36610166)

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scientific article published on 13 March 2007

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English	Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).	scientific article published on 13 March 2007

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scholarly article

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27 December 2019

Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO) (English)

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27 December 2019

multicenter clinical trial

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Enrico Franceschi

1

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27 December 2019

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Giovanni Tallini

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Alba A. Brandes

13

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author name string

G Cavallo

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E Magrini

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A Tosoni

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D Grosso

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L Scopece

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V Blatt

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B Urbini

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L Crinò

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language of work or name

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publication date

13 March 2007

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27 December 2019

British Journal of Cancer

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27 December 2019

96

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1047-1051

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27 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.bjc.6603669

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Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

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EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

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Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial

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Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected].

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Phase II trial of gefitinib in recurrent glioblastoma

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Phase I pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefitinib ('Iressa', ZD1839) in Japanese patients with solid malignant tumors

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Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa).

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20 September 2018

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7 January 2021

based on heuristic

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Identifiers

10.1038/SJ.BJC.6603669

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27 December 2019

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27 December 2019

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27 December 2019

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