Gene delivery by cationic lipid vectors: overcoming cellular barriers (Q36613594)

15 August 2017

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title

Gene delivery by cationic lipid vectors: overcoming cellular barriers (English)

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15 August 2017

Inge S Zuhorn

1

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PubMed ID

17019592

15 August 2017

Jan B F N Engberts

series ordinal

2

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PubMed ID

17019592

15 August 2017

Dick Hoekstra

series ordinal

3

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15 August 2017

22 September 2006

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European Biophysics Journal

15 August 2017

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15 August 2017

36

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15 August 2017

4-5

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15 August 2017

349-362

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https://scigraph.springernature.com/pub.10.1007/s00249-006-0092-4

15 August 2017

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Efficient transfer of chromosome-based DNA constructs into mammalian cells

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Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles

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Interference of poly(ethylene glycol)-lipid analogues with cationic-lipid-mediated delivery of oligonucleotides; role of lipid exchangeability and non-lamellar transitions

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Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis

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12 December 2020

Recharging cationic DNA complexes with highly charged polyanions for in vitro and in vivo gene delivery

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12 December 2020

New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: lipid-DNA complexes for gene delivery.

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Characterization and transfection properties of lipoplexes stabilized with novel exchangeable polyethylene glycol-lipid conjugates.

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12 December 2020

Intracellular trafficking of nonviral vectors

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12 December 2020

Barriers to carrier mediated drug and gene delivery to brain tumors

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12 December 2020

Lipoplexes formed from sugar-based gemini surfactants undergo a lamellar-to-micellar phase transition at acidic pH. Evidence for a non-inverted membrane-destabilizing hexagonal phase of lipoplexes.

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12 December 2020

The mechanism of lamellar-to-inverted hexagonal phase transitions in phosphatidylethanolamine: implications for membrane fusion mechanisms

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12 December 2020

Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER

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12 December 2020

Lipid bilayer vesicle fusion: intermediates captured by high-speed microfluorescence spectroscopy

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12 December 2020

Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes

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Insider information: what viruses tell us about endocytosis

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12 December 2020

Syndecan-1 and syndecan-4 can mediate the invasion of OpaHSPG-expressing Neisseria gonorrhoeae into epithelial cells

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12 December 2020

Exploitation of mammalian host cell functions by bacterial pathogens

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12 December 2020

The potential role of proteoglycans in cationic lipid-mediated gene delivery. Studies of the interaction of cationic lipid-DNA complexes with model glycosaminoglycans

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12 December 2020

Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells

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12 December 2020

Structural and fusogenic properties of cationic liposomes in the presence of plasmid DNA.

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12 December 2020

Quantitative comparison of intracellular trafficking and nuclear transcription between adenoviral and lipoplex systems

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12 December 2020

Implications of lipid microdomains for membrane curvature, budding and fission

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12 December 2020

Targeting caveolae for vesicular drug transport.

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12 December 2020

PS exposure increases the susceptibility of cells to fusion with DOTAP liposomes.

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12 December 2020

The effect of PS content on the ability of natural membranes to fuse with positively charged liposomes and lipoplexes

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12 December 2020

Cell biology. Caveolae--not just craters in the cellular landscape

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12 December 2020

Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine-DNA complexes and the efficiency of gene delivery.

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12 December 2020

Formation and intracellular trafficking of lipoplexes and polyplexes

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12 December 2020

Cationic lipid-DNA complexes-lipoplexes-for gene transfer and therapy

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12 December 2020

Intracellular route and transcriptional competence of polyethylenimine-DNA complexes

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12 December 2020

Potocytosis and cellular exit of complexes as cellular pathways for gene delivery by polycations

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12 December 2020

Phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency.

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12 December 2020

Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides

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12 December 2020

Ligation of cell surface heparan sulfate proteoglycans by antibody-coated beads stimulates phagocytic uptake into epithelial cells: a model for cellular invasion by Neisseria gonorrhoeae.

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Gene therapeutic approaches-transfer in vivo

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Selective gene delivery for cancer therapy using cationic liposomes: in vivo proof of applicability.

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Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection

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Transfection mediated by pH-sensitive sugar-based gemini surfactants; potential for in vivo gene therapy applications

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12 December 2020

On the kinetics of polyplex endocytic trafficking: implications for gene delivery vector design.

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Novel pyridinium surfactants for efficient, nontoxic in vitro gene delivery

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12 December 2020

On the mechanism of cationic amphiphile-mediated transfection. To fuse or not to fuse: is that the question?

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12 December 2020

Liposomes composed of a double-chain cationic amphiphile (vectamidine) induce their own encapsulation into human erythrocytes

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12 December 2020

Hydration of lipoplexes commonly used in gene delivery: follow-up by laurdan fluorescence changes and quantification by differential scanning calorimetry

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12 December 2020

Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis

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12 December 2020

Roles of lipid polymorphism in intracellular delivery

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12 December 2020

DNA release from lipoplexes by anionic lipids: correlation with lipid mesomorphism, interfacial curvature, and membrane fusion

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12 December 2020

Effects of divalent cations and pH on phosphatidylserine model membranes: a 31P NMR study

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12 December 2020

Surface charge markedly attenuates the nonlamellar phase-forming propensities of lipid bilayer membranes: calorimetric and (31)P-nuclear magnetic resonance studies of mixtures of cationic, anionic, and zwitterionic lipids

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12 December 2020

The influence of poly(L-lysine) on phospholipid polymorphism. Evidence that electrostatic polypeptide-phospholipid interactions can modulate bilayer/non-bilayer transitions

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12 December 2020

Interference of serum with lipoplex-cell interaction: modulation of intracellular processing

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12 December 2020

Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery

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12 December 2020

DOTAP (and other cationic lipids): chemistry, biophysics, and transfection

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12 December 2020

Involvement of cellular caveolae in bacterial entry into mast cells.

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12 December 2020

Transbilayer redistribution of phosphatidylethanolamine during fusion of phospholipid vesicles. Dependence on fusion rate, lipid phase separation, and formation of nonbilayer structures

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12 December 2020

Phase behavior, DNA ordering, and size instability of cationic lipoplexes. Relevance to optimal transfection activity

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12 December 2020

GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery

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12 December 2020

Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes

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12 December 2020

DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action

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12 December 2020

Three-Dimensional Imaging of Lipid Gene-Carriers: Membrane Charge Density Controls Universal Transfection Behavior in Lamellar Cationic Liposome-DNA Complexes

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12 December 2020

Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression

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12 December 2020

The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems.

1 reference

12 December 2020

Use of poly(ethylene glycol)-lipid conjugates to regulate the surface attributes and transfection activity of lipid-DNA particles

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12 December 2020

Atomic force microscopy for studying gene transfection mediated by cationic liposomes with a cationic cholesterol derivative

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12 December 2020

Cationic lipid-mediated transfection in vitro and in vivo (review).

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12 December 2020

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

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12 December 2020

The role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids.

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12 December 2020

Application of membrane-active peptides for nonviral gene delivery

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12 December 2020

Antisense oligonucleotides reach mRNA targets via the RNA matrix: downregulation of the 5-HT1A receptor

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12 December 2020

Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection efficiency

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12 December 2020

Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes

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12 December 2020

Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: an artificial viral-like delivery system

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12 December 2020

The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer

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12 December 2020

Phase behavior and aggregate structure in mixtures of dioleoylphosphatidylethanolamine and poly(ethylene glycol)-lipids

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12 December 2020

Characterization of the inhibitory effect of PEG-lipid conjugates on the intracellular delivery of plasmid and antisense DNA mediated by cationic lipid liposomes

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12 December 2020

Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations

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12 December 2020

Physical principles of membrane organization

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12 December 2020

A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin.

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12 December 2020

Mechanisms of lipoplex formation: dependence of the biological properties of transfection complexes on formulation procedures

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12 December 2020

Melittin enables efficient vesicular escape and enhanced nuclear access of nonviral gene delivery vectors

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12 December 2020

A columnar phase of dendritic lipid-based cationic liposome-DNA complexes for gene delivery: hexagonally ordered cylindrical micelles embedded in a DNA honeycomb lattice.

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12 December 2020

Association of the caveola vesicular system with cellular entry by filoviruses

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12 December 2020

Transfection efficiency and uptake process of polyplexes in human lung endothelial cells: a comparative study in non-polarized and polarized cells.

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12 December 2020

Targeting endothelium and its dynamic caveolae for tissue-specific transcytosis in vivo: a pathway to overcome cell barriers to drug and gene delivery

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12 December 2020

An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery

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12 December 2020

Protein-glycosaminoglycan interactions: infectiological aspects

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12 December 2020

Evidence for the role of proteoglycans in cation-mediated gene transfer

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12 December 2020

Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes

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12 December 2020

Lipid rafts and caveolae as portals for endocytosis: new insights and common mechanisms

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12 December 2020

Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery

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12 December 2020

DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression

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12 December 2020

On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids

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12 December 2020

Design and gene delivery activity of modified polyethylenimines.

1 reference

12 December 2020

Structure-activity relationship in cationic lipid mediated gene transfection.

1 reference

12 December 2020

Combinatorial synthesis of new cationic lipids and high-throughput screening of their transfection properties

1 reference

12 December 2020

Transfection Mediated by Gemini Surfactants: Engineered Escape from the Endosomal Compartment

1 reference

12 December 2020

10.1007/S00249-006-0092-4

Identifiers

DOI

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15 August 2017

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PubMed ID

17019592