Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands (Q36617985)

15 August 2017

1 reference

title

Chemistry and biology of the immunophilins and their immunosuppressive ligands (English)

1 reference

15 August 2017

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands (English)

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

3 November 2022

1 reference

lymphocyte activation

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1702904

3 November 2022

author name string

S. L. Schreiber

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1702904

3 November 2022

language of work or name

English

0 references

publication date

1 January 1991

1 reference

15 August 2017

18 January 1991

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1702904

full work available at URL

3 November 2022

number of pages

5

1 reference

based on heuristic

inferred from page(s)

https://syndication.highwire.org/content/doi/10.1126/science.1702904

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

3 November 2022

1 reference

15 August 2017

251

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15 August 2017

4991

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15 August 2017

283-287

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Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

15 August 2017

2

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Probing Immunosuppressant Action with a Nonnatural Immunophilin Ligand

3 November 2022

3

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

The affairs of daughterless and the promiscuity of developmental regulators

3 November 2022

6

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Contingent genetic regulatory events in T lymphocyte activation

3 November 2022

7

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

3 November 2022

9

144

251

1990

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

3 November 2022

10

144

1418

1990

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Transplantation Proceedings

3 November 2022

11

20

51

1988

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation

3 November 2022

12

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Kinetic beta-deuterium isotope effects suggest a covalent mechanism for the protein folding enzyme peptidylprolyl cis/trans-isomerase

3 November 2022

13

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

3 November 2022

14

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

A comparison of cyclosporine binding by cyclophilin and calmodulin and the identification of a novel 45 KD cyclosporine-binding phosphoprotein in Jurkat cells.

3 November 2022

15

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Rapamycin and FK506 binding proteins (immunophilins)

3 November 2022

16

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

International journal of peptide and protein research

3 November 2022

17

19

123

1982

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta

3 November 2022

19

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Cyclophilin: a specific cytosolic binding protein for cyclosporin A

3 November 2022

20

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

3 November 2022

22

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Mechanistic studies of peptidyl prolyl cis-trans isomerase: evidence for catalysis by distortion

3 November 2022

23

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes

3 November 2022

24

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

3 November 2022

25

144

2659

1990

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Cytoplasmic anchoring proteins and the control of nuclear localization

3 November 2022

26

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Towards a better definition of human leucocyte surface molecules.

3 November 2022

27

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

A second cyclophilin-related gene in Saccharomyces cerevisiae

3 November 2022

28

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis

3 November 2022

29

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Peptidyl-prolyl cis-trans-isomerase from Escherichia coli: a periplasmic homolog of cyclophilin that is not inhibited by cyclosporin A.

3 November 2022

30

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Complementary DNA encoding the human T-cell FK506-binding protein, a peptidylprolyl cis-trans isomerase distinct from cyclophilin

3 November 2022

31

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Transplantation Proceedings

3 November 2022

35

19

3520

1987

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

3 November 2022

Cyclosporine

36

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

3 November 2022

Activators and targets

37

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Cyclophilin binds to the region of cyclosporine involved in its immunosuppressive activity

3 November 2022

38

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Inhibition of FKBP rotamase activity by immunosuppressant FK506: twisted amide surrogate.

3 November 2022

39

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Polypeptide chain binding proteins: catalysts of protein folding and related processes in cells

3 November 2022

40

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Drosophila ninaA gene encodes an eye-specific cyclophilin (cyclosporine A binding protein)

3 November 2022

41

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Identification of a putative regulator of early T cell activation genes

3 November 2022

43

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

The ninaA gene required for visual transduction in Drosophila encodes a homologue of cyclosporin A-binding protein

3 November 2022

44

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

The effect of cyclosporine on the use of hospital resources for kidney transplantation.

3 November 2022

45

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

3 November 2022

46

143

1580

1989

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

3 November 2022

47

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Molecular cloning and overexpression of the human FK506-binding protein FKBP

3 November 2022

48

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Hepatotrophic effects of FK506 in dogs

3 November 2022

49

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Kidney transplantation under FK 506

3 November 2022

50

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Liver transplantation (2).

3 November 2022

52

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

3 November 2022

53

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

FK-506--how much potential?

3 November 2022

54

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

3 November 2022

55

143

718

1989

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Sensitivity to cyclosporin A is mediated by cyclophilin in Neurospora crassa and Saccharomyces cerevisiae.

3 November 2022

56

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

Isolation and sequence of an FK506-binding protein from N. crassa which catalyses protein folding

3 November 2022

57

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1702904

3 November 2022

Identifiers

1 reference

15 August 2017

1 reference