The echinocandins: comparison of their pharmacokinetics, pharmacodynamics and clinical applications (Q36626518)

15 August 2017

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title

The echinocandins: comparison of their pharmacokinetics, pharmacodynamics and clinical applications (English)

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15 August 2017

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Claudia Wagner

1

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15 August 2017

Wolfgang Graninger

series ordinal

2

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15 August 2017

Elisabeth Presterl

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3

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15 August 2017

Christian Joukhadar

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4

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15 August 2017

17 October 2006

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15 August 2017

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15 August 2017

78

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15 August 2017

4

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15 August 2017

161-177

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Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study

15 August 2017

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Antifungal drug resistance in Aspergillus

21 January 2018

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Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences

21 January 2018

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Echinocandins and pneumocandins--a new antifungal class with a novel mode of action

21 January 2018

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Effects of amino acid and trace element supplementation on pneumocandin production by Glarea lozoyensis: impact on titer, analogue levels, and the identification of new analogues of pneumocandin B(0).

21 January 2018

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Metabolites of microorganisms. 143. Echinocandin B, a novel polypeptide-antibiotic from Aspergillus nidulans var. echinulatus: isolation and structural components

21 January 2018

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Fungal ß(1,3)-D-glucan synthesis

21 January 2018

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Suitability of caspofungin for aerosol delivery: physicochemical profiling and nebulizer choice

21 January 2018

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Aspergillus fumigatus cell wall: composition and biosynthesis

21 January 2018

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The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase

21 January 2018

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Characterization and gene cloning of 1,3-beta-D-glucan synthase from Saccharomyces cerevisiae

21 January 2018

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Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase

21 January 2018

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Glucan synthase complex of Aspergillus fumigatus

21 January 2018

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Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates

21 January 2018

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Overexpression of Sbe2p, a Golgi protein, results in resistance to caspofungin in Saccharomyces cerevisiae

21 January 2018

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The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin.

21 January 2018

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Progressive esophagitis caused by Candida albicans with reduced susceptibility to caspofungin.

21 January 2018

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Emergence of disseminated candidiasis caused by Candida krusei during treatment with caspofungin: case report and review of literature

21 January 2018

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Emergence of a Candida krusei isolate with reduced susceptibility to caspofungin during therapy

21 January 2018

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In vitro susceptibilities of Candida spp. to caspofungin: four years of global surveillance

21 January 2018

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Assessment of the paradoxical effect of caspofungin in therapy of candidiasis

21 January 2018

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Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans

21 January 2018

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In vitro pharmacodynamic properties of MK-0991 determined by time-kill methods

21 January 2018

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In vitro activity of micafungin (FK-463) against Candida spp.: microdilution, time-kill, and postantifungal-effect studies

21 January 2018

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Efficacy of the echinocandin caspofungin against disseminated aspergillosis and candidiasis in cyclophosphamide-induced immunosuppressed mice

21 January 2018

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Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistently neutropenic rabbits

21 January 2018

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Pharmacodynamics of caspofungin in a murine model of systemic candidiasis: importance of persistence of caspofungin in tissues to understanding drug activity

21 January 2018

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The antifungal echinocandin caspofungin acetate kills growing cells of Aspergillus fumigatus in vitro

21 January 2018

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Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate

21 January 2018

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Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of pulmonary aspergillosis

21 January 2018

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Efficacies of two new antifungal agents, the triazole ravuconazole and the echinocandin LY-303366, in an experimental model of invasive aspergillosis

21 January 2018

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Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-beta-D-glucan synthase

21 January 2018

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Echinocandin antifungal drugs

21 January 2018

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Single- and multiple-dose pharmacokinetics of caspofungin in healthy men.

21 January 2018

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Disposition of caspofungin: role of distribution in determining pharmacokinetics in plasma

21 January 2018

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Influence of human serum on antifungal pharmacodynamics with Candida albicans

21 January 2018

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Pharmacokinetics of micafungin in healthy volunteers, volunteers with moderate liver disease, and volunteers with renal dysfunction

21 January 2018

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Impact of plasma protein binding on antimicrobial activity using time-killing curves

21 January 2018

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Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant

21 January 2018

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Population pharmacokinetic analysis of anidulafungin, an echinocandin antifungal

21 January 2018

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Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs.

21 January 2018

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Anidulafungin: review of a new echinocandin antifungal agent

21 January 2018

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Pharmacokinetics, safety, and tolerability of caspofungin in children and adolescents

21 January 2018

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Safety, tolerability, and pharmacokinetics of Micafungin (FK463) in febrile neutropenic pediatric patients

21 January 2018

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Safety and pharmacokinetics of intravenous anidulafungin in children with neutropenia at high risk for invasive fungal infections

21 January 2018

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Hepatic uptake of the novel antifungal agent caspofungin

21 January 2018

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The changes in some hydrolytic enzymes in carbon tetrachloride-induced fatty livers

21 January 2018

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In vitro evaluation of cytochrome P450-mediated drug interactions between cytarabine, idarubicin, itraconazole and caspofungin

21 January 2018

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Concomitant tacrolimus and micafungin pharmacokinetics in healthy volunteers

21 January 2018

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Concomitant cyclosporine and micafungin pharmacokinetics in healthy volunteers

21 January 2018

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Potential for interactions between caspofungin and nelfinavir or rifampin

21 January 2018

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Rifamycin SV and rifampicin exhibit differential inhibition of the hepatic rat organic anion transporting polypeptides, Oatp1 and Oatp2.

21 January 2018

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Compartmental pharmacokinetics and tissue distribution of the antifungal echinocandin lipopeptide micafungin (FK463) in rabbits

21 January 2018

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Pharmacokinetic and pharmacodynamic modeling of anidulafungin (LY303366): reappraisal of its efficacy in neutropenic animal models of opportunistic mycoses using optimal plasma sampling

21 January 2018

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In vitro interactions of anidulafungin with azole antifungals, amphotericin B and 5-fluorocytosine against Candida species

21 January 2018

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Prophylactic effect of FK463, a novel antifungal lipopeptide, against Pneumocystis carinii infection in mice

21 January 2018

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Caspofungin susceptibility testing of isolates from patients with esophageal candidiasis or invasive candidiasis: relationship of MIC to treatment outcome

21 January 2018

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Comparison of caspofungin and amphotericin B for invasive candidiasis

21 January 2018

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Activities of caspofungin, itraconazole, posaconazole, ravuconazole, voriconazole, and amphotericin B against 448 recent clinical isolates of filamentous fungi

21 January 2018

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Antifungal susceptibility survey of 2,000 bloodstream Candida isolates in the United States.

21 January 2018

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Comparison of two methods and three end points in determination of in vitro activity of micafungin against Aspergillus spp.

21 January 2018

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Sequential therapy with caspofungin and fluconazole for Candida albicans infection

21 January 2018

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Efficacy of caspofungin combined with amphotericin B against azole-resistant Candida albicans

21 January 2018

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Efficacy of micafungin against deep-seated candidiasis in cyclophosphamide-induced immunosuppressed mice

21 January 2018

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Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of disseminated candidiasis and aspergillosis

21 January 2018

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Efficacies of fluconazole, caspofungin, and amphotericin B in Candida glabrata-infected p47phox-/- knockout mice

21 January 2018

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Treatment of Candida glabrata infection in immunosuppressed mice by using a combination of liposomal amphotericin B with caspofungin or micafungin

21 January 2018

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In vivo activity of micafungin in a persistently neutropenic murine model of disseminated infection caused by Candida tropicalis

21 January 2018

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Caspofungin: antifungal activity in vitro, pharmacokinetics, and effects on fungal load and animal survival in neutropenic rats with invasive pulmonary aspergillosis

21 January 2018

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Efficacy of caspofungin alone and in combination with voriconazole in a Guinea pig model of invasive aspergillosis

21 January 2018

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Efficacy of micafungin alone or in combination against systemic murine aspergillosis

21 January 2018

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Effect of amphotericin B and micafungin combination on survival, histopathology, and fungal burden in experimental aspergillosis in the p47phox-/- mouse model of chronic granulomatous disease.

21 January 2018

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Activity of micafungin (FK463) against an itraconazole-resistant strain of Aspergillus fumigatus and a strain of Aspergillus terreus demonstrating in vivo resistance to amphotericin B.

21 January 2018

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Antifungal efficacy of caspofungin (MK-0991) in experimental pulmonary aspergillosis in persistently neutropenic rabbits: pharmacokinetics, drug disposition, and relationship to galactomannan antigenemia

21 January 2018

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Pharmacodynamics of caspofungin in a murine model of invasive pulmonary aspergillosis: evidence of concentration-dependent activity

21 January 2018

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Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia

21 January 2018

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Open-label, randomized comparison of itraconazole versus caspofungin for prophylaxis in patients with hematologic malignancies

21 January 2018

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Micafungin versus fluconazole for prophylaxis against invasive fungal infections during neutropenia in patients undergoing hematopoietic stem cell transplantation

21 January 2018

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Second-line therapy with caspofungin for mucosal or invasive candidiasis: results from the caspofungin compassionate-use study

21 January 2018

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International, open-label, noncomparative, clinical trial of micafungin alone and in combination for treatment of newly diagnosed and refractory candidemia.

21 January 2018

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Phase 2, randomized, dose-ranging study evaluating the safety and efficacy of anidulafungin in invasive candidiasis and candidemia

21 January 2018

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Response and relapse rates of candidal esophagitis in HIV-infected patients treated with caspofungin

21 January 2018

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A randomized double-blind study of caspofungin versus amphotericin for the treatment of candidal esophagitis

21 January 2018

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Randomized, double-blind, multicenter study of caspofungin versus amphotericin B for treatment of oropharyngeal and esophageal candidiases

21 January 2018

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A randomized double-blind study of caspofungin versus fluconazole for the treatment of esophageal candidiasis

21 January 2018

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Efficacy of caspofungin in the treatment of esophageal candidiasis resistant to fluconazole

21 January 2018

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A randomized, double-blind, parallel-group, dose-response study of micafungin compared with fluconazole for the treatment of esophageal candidiasis in HIV-positive patients

21 January 2018

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A randomized, double-blind trial of anidulafungin versus fluconazole for the treatment of esophageal candidiasis

21 January 2018

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Efficacy and safety of caspofungin for treatment of invasive aspergillosis in patients refractory to or intolerant of conventional antifungal therapy

21 January 2018

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Salvage therapy with caspofungin for invasive aspergillosis: results from the caspofungin compassionate use study

21 January 2018

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Successful treatment of oesophageal candidiasis by micafungin: a novel systemic antifungal agent

21 January 2018

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Retrospective study of the hepatic safety profile of patients concomitantly treated with caspofungin and cyclosporin A.

21 January 2018

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Safety and tolerability of caspofungin acetate in the treatment of fungal infections

21 January 2018

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Effects of the antifungal agents on oxidative drug metabolism: clinical relevance

21 January 2018

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Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis

21 January 2018

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Assessment of the safety and pharmacokinetics of anidulafungin when administered with cyclosporine

21 January 2018

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WF11899A, B and C, novel antifungal lipopeptides. I. Taxonomy, fermentation, isolation and physico-chemical properties.

21 January 2018

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.47.1084

Identifiers

DOI

10.1159/000096348

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15 August 2017

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