Oxidative and nitrosative stress in pediatric pulmonary hypertension: roles of endothelin-1 and nitric oxide (Q36627420)

15 August 2017

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title

Oxidative and nitrosative stress in pediatric pulmonary hypertension: roles of endothelin-1 and nitric oxide (English)

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15 August 2017

pulmonary hypertension

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Stephen M Black

1

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PubMed ID

17049313

15 August 2017

Jeffrey R Fineman

series ordinal

2

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PubMed ID

17049313

15 August 2017

language of work or name

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18 August 2006

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15 August 2017

Vascular Pharmacology

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15 August 2017

45

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15 August 2017

5

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15 August 2017

308-316

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Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia

15 August 2017

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Cloning and expression of a cDNA encoding an endothelin receptor

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Expression and developmental profile of antioxidant enzymes in human lung and liver.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Rebound pulmonary hypertension after inhalation of nitric oxide

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Coordinated regulation of genes of the nitric oxide and endothelin pathways during the development of pulmonary hypertension in fetal lambs

7 January 2021

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Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide

7 January 2021

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Augmentation of hypoxic pulmonary vasoconstriction in the isolated perfused rat lung by in vitro antagonists of endothelium-dependent relaxation

7 January 2021

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The overexpression of copper-zinc superoxide dismutase protects NOS III from nitric oxide-mediated inhibition

7 January 2021

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The overexpression catalase reduces NO-mediated inhibition of endothelial NO synthase

7 January 2021

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Increased superoxide generation is associated with pulmonary hypertension in fetal lambs: a role for NADPH oxidase

7 January 2021

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Nitric oxide activates p21ras and leads to the inhibition of endothelial NO synthase by protein nitration

7 January 2021

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Overexpression of human catalase inhibits proliferation and promotes apoptosis in vascular smooth muscle cells

7 January 2021

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Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

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The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases

7 January 2021

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Tone-dependent responses to endothelin in the isolated perfused fetal sheep pulmonary circulation in situ

7 January 2021

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Impairment of endothelium-dependent pulmonary artery relaxation in children with congenital heart disease and abnormal pulmonary hemodynamics

7 January 2021

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Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells

7 January 2021

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An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension

7 January 2021

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Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR.

7 January 2021

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Life-threatening effects of discontinuing inhaled nitric oxide in children

7 January 2021

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A randomized, controlled study of the 1-hour and 24-hour effects of inhaled nitric oxide therapy in children with acute hypoxemic respiratory failure

7 January 2021

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Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial. Inhaled Nitric Oxide in ARDS Study Group

7 January 2021

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Impairment of pulmonary endothelium-dependent relaxation in patients with Eisenmenger's syndrome

7 January 2021

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Multicenter randomized controlled trial of the effects of inhaled nitric oxide therapy on gas exchange in children with acute hypoxemic respiratory failure.

7 January 2021

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Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide

7 January 2021

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Receptor-regulated dynamic S-nitrosylation of endothelial nitric-oxide synthase in vascular endothelial cells

7 January 2021

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Role of endothelin-1 in lung disease

7 January 2021

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Regulation of pulmonary vascular tone in the perinatal period

7 January 2021

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Preparation for birth into an O2-rich environment: the antioxidant enzymes in the developing rabbit lung

7 January 2021

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Clearance of circulating endothelin-1 by ETB receptors in rats

7 January 2021

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Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells

7 January 2021

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Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Expression of endothelin-1 in the lungs of patients with pulmonary hypertension.

7 January 2021

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Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS.

7 January 2021

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Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology

7 January 2021

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Postnatal changes in endothelin-1 binding in porcine pulmonary vessels and airways.

7 January 2021

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Endothelin-stimulated monocyte supernatants enhance neutrophil superoxide production.

7 January 2021

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Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells

7 January 2021

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Chronic treatment with probucol effectively inhibits progression of pulmonary hypertension in rats

7 January 2021

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Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation

7 January 2021

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Developmental changes in endothelin expression and activity in the ovine fetal lung

7 January 2021

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Malformations induced in cultured rat embryos by enzymically generated active oxygen species

7 January 2021

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Endothelin production links superoxide generation to altered opioid-induced pial artery vasodilation after brain injury in pigs

7 January 2021

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Superoxide anion and endothelial regulation of arterial tone

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Nitric oxide decreases endothelin-1 secretion through the activation of soluble guanylate cyclase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Randomized, multicenter trial of inhaled nitric oxide and high-frequency oscillatory ventilation in severe, persistent pulmonary hypertension of the newborn

7 January 2021

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Endothelin-1 has a priming effect on production of superoxide anion by alveolar macrophages: its possible correlation with bronchopulmonary dysplasia

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Transforming growth factor-beta stimulates the expression of endothelin mRNA by vascular endothelial cells

7 January 2021

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Endothelin-1 and the regulation of vascular tone

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform

7 January 2021

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Redox regulation of cell signalling

7 January 2021

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A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Life-threatening effects of discontinuing inhaled nitric oxide in severe respiratory failure

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Inhibition by L-arginine of the endothelin-mediated increase in cytosolic calcium in human neutrophils

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Superoxide regulation of endothelin-converting enzyme

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Interaction between endothelin-1 and endothelium-derived relaxing factor in human arteries and veins

7 January 2021

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Endothelin-1 release from endothelial cells in culture is elevated both acutely and chronically by short periods of mechanical stretch

7 January 2021

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Transcriptional regulation of the endothelin-1 gene by TNF-alpha

7 January 2021

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Superoxide anion release by human endothelial cells: synergism between a phorbol ester and a calcium ionophore

7 January 2021

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Vascular endothelial growth factor increases endothelin-converting enzyme expression in vascular endothelial cells

7 January 2021

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Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development.

7 January 2021

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Long-Term Treatment With Oral Sildenafil Is Safe and Improves Functional Capacity and Hemodynamics in Patients With Pulmonary Arterial Hypertension

7 January 2021

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Rebound pulmonary hypertension on withdrawal from inhaled nitric oxide

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2006.08.005

Endothelin-converting enzyme expression in the rat vascular injury model and human coronary atherosclerosis

7 January 2021

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S-Nitrosation and regulation of inducible nitric oxide synthase

7 January 2021

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Effects of endogenous and exogenous nitric oxide on endothelin-1 production in cultured vascular endothelial cells

7 January 2021

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Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease?

7 January 2021

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Structural and Functional Analysis of a Mutant Ras Protein That Is Insensitive to Nitric Oxide Activation†

7 January 2021

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Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance

7 January 2021

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Cyclic guanosine monophosphate as a mediator of vasodilation

7 January 2021

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Interaction between endothelium-derived relaxing factors, S-nitrosothiols, and endothelin-1 on Ca2+ mobilization in rat vascular smooth muscle cells

7 January 2021

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Vascular endothelial cells synthesize nitric oxide from L-arginine

7 January 2021

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Inhaled nitric oxide increases endothelin-1 levels: a potential cause of rebound pulmonary hypertension

7 January 2021

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Antioxidant enzyme regulation and resistance to oxidants of human bronchial epithelial cells cultured under hyperoxic conditions

7 January 2021

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S-nitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity

7 January 2021

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Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells

7 January 2021

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Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The Inhaled Nitric Oxide Study Group.

7 January 2021

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The pathogenesis of atherosclerosis: a perspective for the 1990s

7 January 2021

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Reciprocal regulation of endothelin-1 and nitric oxide: relevance in the physiology and pathology of the cardiovascular system.

7 January 2021

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Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

7 January 2021

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Inhaled nitric oxide in premature infants with the respiratory distress syndrome.

7 January 2021

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Genomic analysis and expression patterns reveal distinct genes for endothelial and brain nitric oxide synthase

7 January 2021

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Functionally distinct endothelin B receptors in vascular endothelium and smooth muscle

7 January 2021

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Cloning and functional expression of human endothelin-converting enzyme cDNA

7 January 2021

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Nitric oxide gas decreases endothelin-1 mRNA in cultured pulmonary artery endothelial cells

7 January 2021

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7 January 2021

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Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

7 January 2021

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Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 (bosentan)

7 January 2021

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Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway.

7 January 2021

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7 January 2021

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Sildenafil for primary and secondary pulmonary hypertension

7 January 2021

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Molecular mechanisms of nitric oxide-induced growth arrest and apoptosis in fetal pulmonary arterial smooth muscle cells

7 January 2021

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Role of reactive oxygen species in vascular remodeling associated with pulmonary hypertension

7 January 2021

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Endothelin-1 decreases endothelial NOS expression and activity through ETA receptor-mediated generation of hydrogen peroxide

7 January 2021

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ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species

7 January 2021

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Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy

7 January 2021

1 reference

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Increased hydrogen peroxide downregulates soluble guanylate cyclase in the lungs of lambs with persistent pulmonary hypertension of the newborn

7 January 2021

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Developmental effects of endothelin-1 on the pulmonary circulation in sheep.

7 January 2021

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Endothelinb receptor agonists produce pulmonary vasodilation in intact newborn lambs with pulmonary hypertension

7 January 2021

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A novel potent vasoconstrictor peptide produced by vascular endothelial cells

7 January 2021

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Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulation

7 January 2021

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Differential patterns of antioxidant enzyme mRNA expression in guinea pig lung and liver during development.

7 January 2021

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Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite

7 January 2021

1 reference

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Nitric oxide synthesis in endothelial cytosol: evidence for a calcium-dependent and a calcium-independent mechanism

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VPH.2006.08.005

1 reference

15 August 2017

1 reference

PubMed ID

17049313