Monitoring the health to disease continuum with global metabolic profiling and systems biology (Q36630002)

15 August 2017

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title

Monitoring the health to disease continuum with global metabolic profiling and systems biology (English)

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15 August 2017

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Laura K Schnackenberg

series ordinal

1

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PubMed ID

17054417

15 August 2017

Richard D Beger

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2

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15 August 2017

1 October 2006

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15 August 2017

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15 August 2017

7

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15 August 2017

7

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15 August 2017

1077-1086

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Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks

15 August 2017

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

The challenges of modeling mammalian biocomplexity

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Metabolomics – the link between genotypes and phenotypes

21 January 2018

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'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Parallel analysis of transcript and metabolic profiles: a new approach in systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Metabolomics by numbers: acquiring and understanding global metabolite data

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Metabonomics: a platform for studying drug toxicity and gene function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Metabonomics in toxicology: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies

21 January 2018

1 reference

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Use of selective TOCSY NMR experiments for quantifying minor components in complex mixtures: application to the metabonomics of amino acids in honey

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

HPLC-MS-based methods for the study of metabonomics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Matrix-suppressed laser desorption/ionisation mass spectrometry and its suitability for metabolome analyses

21 January 2018

1 reference

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Lysophosphatidic acid production and action: validated targets in cancer?

21 January 2018

1 reference

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Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass spectrometry and multivariate statistical analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Possibilities of selective screening for inborn errors of metabolism using high-resolution 1H-FT-NMR spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

The application of tandem mass spectrometry to neonatal screening for inherited disorders of intermediary metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Gas chromatographic-mass spectrometric urinary metabolome analysis to study mutations of inborn errors of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Aminoacylase I deficiency: a novel inborn error of metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Medium-chain acyl-CoA dehydrogenase (MCAD) mutations identified by MS/MS-based prospective screening of newborns differ from those observed in patients with clinical symptoms: identification and characterization of a new, prevalent mutation that res

21 January 2018

1 reference

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H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Metabolomics: the principles and potential applications to transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Metabolomic approaches to mitochondrial disease: correlation of urine organic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Detection of epithelial ovarian cancer using 1H-NMR-based metabonomics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Proton nuclear magnetic resonance-based metabonomics for rapid diagnosis of meningitis and ventriculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Large-scale human metabolomics studies: a strategy for data (pre-) processing and validation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Proton nuclear magnetic resonance spectroscopy of body fluids in the field of inborn errors of metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Metabolomic analysis and signatures in motor neuron disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Focused metabolomic profiling in the drug development process: advances from lipid profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

How molecular profiling could revolutionize drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Metabolomic study of cisplatin-induced nephrotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

An integrated study of acute effects of valproic acid in the liver using metabonomics, proteomics, and transcriptomics platforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Metabonomic assessment of vasculitis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Mechanisms and biomarkers of cardiovascular injury induced by phosphodiesterase inhibitor III SK&F 95654 in the spontaneously hypertensive rat.

21 January 2018

1 reference

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Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse

21 January 2018

1 reference

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Metabolomics: an emerging post-genomic tool for nutrition

21 January 2018

1 reference

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The case for strategic international alliances to harness nutritional genomics for public and personal health

21 January 2018

1 reference

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Biofluid 1H NMR-based metabonomic techniques in nutrition research - metabolic effects of dietary isoflavones in humans

21 January 2018

1 reference

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Nutritional management of urea cycle disorders.

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches

21 January 2018

1 reference

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Nutrition and food science go genomic

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Nutrition-/diet-induced changes in gene expression in white adipose tissue

21 January 2018

1 reference

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Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics

21 January 2018

1 reference

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Focused lipidomics by tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

A comprehensive classification system for lipids

21 January 2018

1 reference

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Selective nitros(yl)ation induced in vivo by a nitric oxide-donating cyclooxygenase-2 inhibitor: a NObonomic analysis

21 January 2018

1 reference

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Genomics to fluxomics and physiomics — pathway engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

[1,2-13C2]-D-glucose profiles of the serum, liver, pancreas, and DMBA-induced pancreatic tumors of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Genomics and proteomics analysis of acetaminophen toxicity in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Combination of 'omics' data to investigate the mechanism(s) of hydrazine-induced hepatotoxicity in rats and to identify potential biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

A proposed framework for the description of plant metabolomics experiments and their results

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Summary recommendations for standardization and reporting of metabolic analyses

21 January 2018

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https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Development of public toxicogenomics software for microarray data management and analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Pharmaco-metabonomic phenotyping and personalized drug treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Toxicity classification from metabonomic data using a density superposition approach: ‘CLOUDS’

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Proton NMR analysis of plasma from renal failure patients: Evaluation of sample preparation and spectral-editing methods

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

21 January 2018

1 reference

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Batch statistical processing of1H NMR-derived urinary spectral data

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

Systems Toxicology: Integrated Genomic, Proteomic and Metabonomic Analysis of Methapyrilene Induced Hepatotoxicity in the Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.7.7.1077

10.2217/14622416.7.7.1077

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17054417