Interleukin 6: from bench to bedside (Q36639873)

15 August 2017

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title

Interleukin 6: from bench to bedside (English)

1 reference

15 August 2017

Norihiro Nishimoto

1

1 reference

PubMed ID

17075601

15 August 2017

Tadamitsu Kishimoto

series ordinal

2

1 reference

15 August 2017

1 November 2006

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Nature Clinical Practice Rheumatology

15 August 2017

1 reference

15 August 2017

2

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15 August 2017

619-626

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15 August 2017

11

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Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

15 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Interleukin-6: historical background, genetics and biological significance

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Phase I trial of subcutaneous interleukin-6 in patients with advanced malignancies

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Interleukin-6 (IL-6) functions as an in vitro autocrine growth factor in renal cell carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

IgG1 plasmacytosis in interleukin 6 transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

New drugs for rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Interleukin-6 in synovial fluid is closely associated with chronic synovitis in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Serum interleukin 6 levels in rheumatoid arthritis: correlations with clinical and laboratory indices of disease activity

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

IL-6 promoter polymorphism in patients with rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Interleukin 6 is required for the development of collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Delayed onset and reduced severity of collagen-induced arthritis in interleukin-6-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Distinct contribution of IL-6, TNF-alpha, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Humanized antibody to human interleukin-6 receptor inhibits the development of collagen arthritis in cynomolgus monkeys

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: a randomized, double-blind, placebo-controlled, dose-escalation trial

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Intravenous iron therapy for severe anaemia in systemic-onset juvenile chronic arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Efficacy of etanercept for the treatment of juvenile idiopathic arthritis according to the onset type

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Interleukin 6 as a therapeutic target in systemic-onset juvenile idiopathic arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

The -174G allele of the interleukin-6 gene confers susceptibility to systemic arthritis in children: a multicenter study using simplex and multiplex juvenile idiopathic arthritis families

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Therapeutic efficacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

1 reference

7 January 2021

Humanized monoclonal anti-interleukin-6 receptor antibody for treatment of intractable adult-onset Still's disease

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

IL-6 is required for the development of Th1 cell-mediated murine colitis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Interleukin-6 and its receptor: a paradigm for cytokines

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Interleukin-6 trans-signalling in chronic inflammation and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Negative regulation of cytokine signaling

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0338

7 January 2021

Identifiers

DOI

10.1038/NCPRHEUM0338

1 reference

15 August 2017

1 reference

PubMed ID

17075601