Reversing drug resistance in bcl-2-expressing tumor cells by depleting glutathione (Q36648390)

15 August 2017

title

Reversing drug resistance in bcl-2-expressing tumor cells by depleting glutathione (English)

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15 August 2017

Voehringer DW

1

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15 August 2017

Meyn RE

series ordinal

2

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15 August 2017

publication date

1 January 1998

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15 August 2017

published in

Drug Resistance Updates

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15 August 2017

volume

1

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15 August 2017

issue

6

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15 August 2017

page(s)

345-351

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Different cell thresholds for commitment to death: a link between carcinogenesis and drug resistance.

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Biochemical modulation of radiation-induced apoptosis in murine lymphoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Apoptosis in murine tumors treated with chemotherapy agents

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Cell death signal transduction and Bcl-2 function

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Programmed cell death induced by ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Ceramide: a stress signal and mediator of growth suppression and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Effect of fatty acids on energy coupling processes in mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Why are mitochondria involved in apoptosis? Permeability transition pores and apoptosis as selective mechanisms to eliminate superoxide-producing mitochondria and cell.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Mitochondrial control of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Effects of N-acetyl-L-cysteine on T-cell apoptosis are not mediated by increased cellular glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Cleavage of CPP32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Mitochondrial control of nuclear apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Intranuclear distribution, function and fate of glutathione and glutathione-S-conjugate in living rat hepatocytes studied by fluorescence microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Differential effects of depleting agents on cytoplasmic and nuclear non-protein sulphydryls: a fluorescence image cytometry study

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Injected cytochrome c induces apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Signal transduction pathways in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

An essential role for free radicals and derived species in signal transduction.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Induction of glutathione synthetase by 1,10-phenanthroline

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Pleiotropic effects of Bcl-2 on transcription factors in T cells: potential role of NF-kappa B p50-p50 for the anti-apoptotic function of Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Thioltransferase (glutaredoxin) is detected within HIV-1 and can regulate the activity of glutathionylated HIV-1 protease in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

The mitochondrial death/life regulator in apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

TUMOUR SULPHYDRYL LEVELS AND SENSITIVITY TO THE NITROGEN MUSTARD MEROPHAN

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

An evaluation of the role of glutathione and its associated enzymes in the expression of differential sensitivities to antitumour agents shown by a range of human tumour cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

The relationship between nuclear glutathione levels and resistance to melphalan in human ovarian tumour cells

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Altered metabolism of glutathione in cells transformed by oncogenes which cause resistance to ionizing radiations

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Rescue of cells from apoptosis by inhibition of active GSH extrusion.

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Depletion of Glutathione in Normal and Malignant Human Cells In Vivo by Buthionine Sulfoximine: Clinical and Biochemical Results

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

Enhancement of the DNA cross-linking activity of melphalan by misonidazole in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1368-7646%2898%2980010-1

7 January 2021

10.1016/S1368-7646(98)80010-1

Identifiers

DOI

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15 August 2017

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