A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease (Q36649213)

15 August 2017

A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease (English)

1 reference

multicenter clinical trial

15 August 2017

0 references

0 references

sickle-cell disease

0 references

author name string

Ted Wun

1

1 reference

15 August 2017

Denis Soulieres

2

1 reference

15 August 2017

Andrew L Frelinger

3

1 reference

15 August 2017

Lakshmanan Krishnamurti

4

1 reference

15 August 2017

Enrico M Novelli

5

1 reference

15 August 2017

Abdullah Kutlar

6

1 reference

15 August 2017

Kenneth I Ataga

7

1 reference

15 August 2017

Charles L Knupp

8

1 reference

15 August 2017

Lillian E McMahon

9

1 reference

15 August 2017

John J Strouse

10

1 reference

15 August 2017

Chunmei Zhou

11

1 reference

15 August 2017

Lori E Heath

12

1 reference

15 August 2017

Chuke E Nwachuku

13

1 reference

15 August 2017

Joseph A Jakubowski

14

1 reference

15 August 2017

Jeffrey S Riesmeyer

15

1 reference

15 August 2017

Kenneth J Winters

16

1 reference

15 August 2017

17 February 2013

1 reference

Journal of Hematology & Oncology

15 August 2017

1 reference

15 August 2017

6

1 reference

15 August 2017

17

1 reference

Creative Commons Attribution 2.0 Generic

15 August 2017

start time

17 February 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

exact match

https://scigraph.springernature.com/pub.10.1186/1756-8722-6-17

0 references

cites work

Association of coagulation activation with clinical complications in sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Daily assessment of pain in adults with sickle cell disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Prasugrel: a novel thienopyridine antiplatelet agent. A review of preclinical and clinical studies and the mechanistic basis for its distinct antiplatelet profile

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Hypercoagulability in sickle cell disease: new approaches to an old problem

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Beta-thalassaemia and sickle cell anaemia as paradigms of hypercoagulability.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Dose-dependent inhibition of human platelet aggregation by prasugrel and its interaction with aspirin in healthy subjects

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Sickle cell vasoocclusion: heterotypic, multicellular aggregations driven by leukocyte adhesion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Hypercoagulability in sickle cell disease: a curious paradox

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Management of sickle cell disease.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Erythrocyte adherence to endothelium in sickle-cell anemia. A possible determinant of disease severity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Inflammatory potential of neutrophils detected in sickle cell disease

28 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-8722-6-17

Coagulation activation and inflammation in sickle cell disease-associated pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-8722-6-17

Platelet activation in patients with sickle cell disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-8722-6-17

Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-8722-6-17

Therapeutic effect of aspirin in sickle cell anaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1756-8722-6-17

Assessment of P2Y(12) inhibition with the point-of-care device VerifyNow P2Y12 in patients treated with prasugrel or clopidogrel coadministered with aspirin

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Understanding pain and improving management of sickle cell disease: the PiSCES study

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Activated polymorphonuclear cells increase sickle red blood cell retention in lung: role of phospholipids

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585853

Aspirin-dipyridamole prophylaxis of sickle cell disease pain crises

20 September 2018

1 reference

12 December 2020

Trial of low doses of aspirin as prophylaxis in sickle cell disease

1 reference

12 December 2020

Clinical and biological double-blind-study of ticlopidine in preventive treatment of sickle-cell disease crises

1 reference

12 December 2020

A double-blind trial of ticlopidine in sickle cell disease

1 reference

12 December 2020

Disturbance of plasma and platelet thrombospondin levels in sickle cell disease

1 reference

12 December 2020

The use of the VerifyNow P2Y12 point-of-care device to monitor platelet function across a range of P2Y12 inhibition levels following prasugrel and clopidogrel administration

1 reference

12 December 2020

Soluble P-selectin and vascular endothelial growth factor in steady state sickle cell disease: relationship to genotype

1 reference

12 December 2020

Intrinsic platelet reactivity before P2Y12 blockade contributes to residual platelet reactivity despite high-level P2Y12 blockade by prasugrel or high-dose clopidogrel. Results from PRINCIPLE-TIMI 44

1 reference

12 December 2020

Thrombogenesis in sickle cell disease

1 reference

12 December 2020

Activated monocytes and platelet-monocyte aggregates in patients with sickle cell disease

1 reference

12 December 2020

Identifiers

DOI

10.1186/1756-8722-6-17

1 reference

Dimensions Publication ID

15 August 2017

1000998454

0 references

Fatcat ID

release_7e4roz2ylrbypmqmm6svu3ntke

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7e4roz2ylrbypmqmm6svu3ntke

24 November 2022

mapped directly with Wikidata item

1 reference

15 August 2017

PubMed publication ID

23414938

1 reference