The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis (Q36650575)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26705366%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

review article

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title

The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26705366%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

0 references

1

1 reference

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3 March 2020

Vincent Algalarrondo

2

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3 March 2020

Stanley Nattel

7

1 reference

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3 March 2020

5

Xander H T Wehrens

1 reference

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3 March 2020

6

Dobromir Dobrev

1 reference

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3 March 2020

author name string

Niels Voigt

3

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3 March 2020

Jonathan Melka

4

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3 March 2020

publication date

23 December 2015

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3 March 2020

published in

Cardiovascular Research

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3 March 2020

volume

109

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3 March 2020

issue

4

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3 March 2020

page(s)

467-479

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The pioneering work of George Mines on cardiac arrhythmias: groundbreaking ideas that remain influential in contemporary cardiac electrophysiology.

3 March 2020

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Comparing the therapeutic effects of carvedilol and metoprolol on prevention of atrial fibrillation after coronary artery bypass surgery, a double-blind study.

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Atrial fibrillation ablation: translating basic mechanistic insights to the patient.

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Arrhythmias, elicited by catecholamines and serotonin, vanish in human chronic atrial fibrillation

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Role of the autonomic nervous system in atrial fibrillation: pathophysiology and therapy

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Symptomatic response to antiarrhythmic drug therapy is modulated by a common single nucleotide polymorphism in atrial fibrillation.

30 September 2017

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30 September 2017

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Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation

30 September 2017

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Ionic determinants of functional reentry in a 2-D model of human atrial cells during simulated chronic atrial fibrillation

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New ideas about atrial fibrillation 50 years on.

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30 September 2017

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A third class of anti-arrhythmic action. Effects on atrial and ventricular intracellular potentials, and other pharmacological actions on cardiac muscle, of MJ 1999 and AH 3474

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The effect of amiodarone, a new anti-anginal drug, on cardiac muscle

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Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs

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The surgical treatment of atrial fibrillation. III. Development of a definitive surgical procedure

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Insights into mechanisms of antiarrhythmic drug action from experimental models of atrial fibrillation

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LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation

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Atrial Fibrillation Activates AMP-Dependent Protein Kinase and its Regulation of Cellular Calcium Handling: Potential Role in Metabolic Adaptation and Prevention of Progression.

28 June 2018

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In silico optimization of atrial fibrillation-selective sodium channel blocker pharmacodynamics

28 June 2018

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Amiodarone blocks inactivated cardiac sodium channels

28 June 2018

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Effect of Sotalol on clinical arrhythmias.

28 June 2018

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Cardioversion with flecainide in patients with atrial fibrillation of recent onset

28 June 2018

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Verapamil associated with quinidine in the treatment of chronic atrial fibrillation

28 June 2018

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Potassium Channel Blockade Enhances Atrial Fibrillation-Selective Antiarrhythmic Effects of Optimized State-Dependent Sodium Channel Blockade.

28 June 2018

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Adenosine-guided pulmonary vein isolation for the treatment of paroxysmal atrial fibrillation: an international, multicentre, randomised superiority trial.

20 September 2018

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Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts.

20 September 2018

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Arrhythmia causes lipid accumulation and reduced glucose uptake.

20 September 2018

1 reference

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Upregulation of K(2P)3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Approaches to catheter ablation for persistent atrial fibrillation.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Atrial fibrillation promotion with long-term repetitive obstructive sleep apnea in a rat model

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Role of small-conductance calcium-activated potassium channels in atrial electrophysiology and fibrillation in the dog.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Atrial supply-demand balance in healthy adult pigs: coronary blood flow, oxygen extraction, and lactate production during acute atrial fibrillation.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Paroxysmal atrial fibrillation and pulmonary veins: relationships between clinical forms and automatic versus re-entrant mechanisms

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Computational models of ventricular- and atrial-like human induced pluripotent stem cell derived cardiomyocytes.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Concomitant obstructive sleep apnea increases the recurrence of atrial fibrillation following radiofrequency catheter ablation of atrial fibrillation: clinical impact of continuous positive airway pressure therapy

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

MK-0448, a specific Kv1.5 inhibitor: safety, pharmacokinetics, and pharmacodynamic electrophysiology in experimental animal models and humans

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Proteomic and metabolomic analysis of atrial profibrillatory remodelling in congestive heart failure

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Mechanisms by which adenosine restores conduction in dormant canine pulmonary veins

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Mechanisms of atrial fibrillation termination by rapidly unbinding Na+ channel blockers: insights from mathematical models and experimental correlates

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Differential behaviors of atrial versus ventricular fibroblasts: a potential role for platelet-derived growth factor in atrial-ventricular remodeling differences

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Combined metabolomic and proteomic analysis of human atrial fibrillation

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Pulmonary vein region ablation in experimental vagal atrial fibrillation: role of pulmonary veins versus autonomic ganglia

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Mechanisms of atrial fibrillation termination by pure sodium channel blockade in an ionically-realistic mathematical model.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

"Dormant" pulmonary vein conduction revealed by adenosine after ostial radiofrequency catheter ablation

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

Cholinergic atrial fibrillation: I(K,ACh) gradients determine unequal left/right atrial frequencies and rotor dynamics

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777910

A randomized, controlled trial of RSD1235, a novel anti-arrhythmic agent, in the treatment of recent onset atrial fibrillation

20 September 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV275

The search for novel antiarrhythmic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV275

Transmural Conduction Is the Predominant Mechanism of Breakthrough During Atrial Fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV275

Obesity results in progressive atrial structural and electrical remodeling: Implications for atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV275

The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential

21 January 2018

1 reference

12 December 2020

Activation of proteolysis by calpains and structural changes in human paroxysmal and persistent atrial fibrillation

1 reference

12 December 2020

Dronedarone in atrial fibrillation--Jekyll and Hyde?

1 reference

12 December 2020

Experimental evidence for proarrhythmic mechanisms of antiarrhythmic drugs

1 reference

12 December 2020

A focal source of atrial fibrillation treated by discrete radiofrequency ablation

1 reference

12 December 2020

Voltage- and time-dependent depression of maximum rate of depolarisation of guinea-pig ventricular action potentials by two new antiarrhythmic drugs, flecainide and lorcainide

1 reference

12 December 2020

The therapy of atrial fibrillation with the combination of hydroquinidine and reserpine

1 reference

12 December 2020

Effects of flecainide and quinidine on human atrial action potentials. Role of rate-dependence and comparison with guinea pig, rabbit, and dog tissues

1 reference

12 December 2020

N-[(omega-amino-1-hydroxyalkyl)phenyl]methanesulfonamide derivatives with class III antiarrhythmic activity

1 reference

12 December 2020

What is an antiarrhythmic drug? From clinical trials to fundamental concepts

1 reference

12 December 2020

Mechanism of flecainide's antiarrhythmic action in experimental atrial fibrillation

1 reference

12 December 2020

Tarantula peptide inhibits atrial fibrillation

1 reference

12 December 2020

Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators

1 reference

12 December 2020

Frequency-dependent effects of amiodarone on atrioventricular nodal function and slow-channel action potentials: evidence for calcium channel-blocking activity

1 reference

12 December 2020

Ionic targets for drug therapy and atrial fibrillation-induced electrical remodeling: insights from a mathematical model

1 reference

12 December 2020

Excitation propagation in nonhomogenous medium (actions analogous to heart fibrillation)

1 reference

12 December 2020

Oral flecainide acetate for the treatment of ventricular arrhythmias

1 reference

12 December 2020

Connexins and atrial fibrillation: filling in the gaps

1 reference

12 December 2020

Irregular rhythm and atrial metabolism are key for the evolution of proarrhythmic atrial remodeling in atrial fibrillation

1 reference

12 December 2020

Rapid pulmonary vein isolation combined with autonomic ganglia modification: a randomized study

1 reference

12 December 2020

Driver Domains in Persistent Atrial Fibrillation

1 reference

12 December 2020

Identifiers

DOI

10.1093/CVR/CVV275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26705366%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26705366%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

26705366

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26705366%20AND%20SRC:MED&resulttype=core&format=json