Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV (Q36654098)

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scientific article published on 20 December 2012

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English	Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV	scientific article published on 20 December 2012

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21 February 2020

Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV (English)

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Ronald G Collman

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Frederic D. Bushman

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Carl H June

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Bruce L. Levine

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Bruce L Levine

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David Stein

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Gwendolyn Binder-Scholl

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Rithun Mukherjee

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Troy Brady

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Tessio Rebello

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Laurent Humeau

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Michael Kalos

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Emmanouil Papasavvas

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Luis J Montaner

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Daniel Schullery

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Farida Shaheen

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Andrea L Brennan

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21 February 2020

Zhaohui Zheng

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21 February 2020

Julio Cotte

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21 February 2020

Vladimir Slepushkin

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21 February 2020

Elizabeth Veloso

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21 February 2020

Adonna Mackley

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21 February 2020

Wei-Ting Hwang

19

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21 February 2020

Faten Aberra

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21 February 2020

Jenny Zhan

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21 February 2020

Jean Boyer

22

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20 December 2012

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21 February 2020

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10

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21 February 2020

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21 February 2020

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21 February 2020

1524-1533

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21 February 2020

Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells

1 reference

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Secreted antiviral entry inhibitory (SAVE) peptides for gene therapy of HIV infection

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30 September 2017

Survival of the fittest: positive selection of CD4+ T cells expressing a membrane-bound fusion inhibitor following HIV-1 infection

1 reference

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30 September 2017

HIV sequence variation associated with env antisense adoptive T-cell therapy in the hNSG mouse model

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Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy.

1 reference

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Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells

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T cell receptor contact to restricting MHC molecules is a prerequisite for peripheral interclonal T cell competition

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Genetic therapies against HIV.

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Impact of gene-modified T cells on HIV infection dynamics

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CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

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Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance

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Theoretical design of a gene therapy to prevent AIDS but not human immunodeficiency virus type 1 infection

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A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread

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30 September 2017

Prolonged survival and tissue trafficking following adoptive transfer of CD4zeta gene-modified autologous CD4(+) and CD8(+) T cells in human immunodeficiency virus-infected subjects

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Resistance of mature T cells to oncogene transformation

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Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV+ infected patients grouped according to CD4 count and viral load

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Peaceful coexistence or clonal dominance?

1 reference

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12 December 2020

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Estimating the benefit of an HIV-1 vaccine that reduces viral load set point

1 reference

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12 December 2020

based on heuristic

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Evidence that intermittent structured treatment interruption, but not immunization with ALVAC-HIV vCP1452, promotes host control of HIV replication: the results of AIDS Clinical Trials Group 5068

1 reference

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12 December 2020

based on heuristic

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Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23264589

12 December 2020

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Identifiers

10.1182/BLOOD-2012-07-447250

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21 February 2020

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21 February 2020

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21 February 2020

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