T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production. (Q36654128)

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20 February 2020

title

T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production (English)

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20 February 2020

7

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20 February 2020

author name string

John C Riches

1

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20 February 2020

Jeffrey K Davies

2

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20 February 2020

Fabienne McClanahan

3

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20 February 2020

Rewas Fatah

4

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20 February 2020

Sameena Iqbal

5

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20 February 2020

Samir Agrawal

6

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20 February 2020

John G Gribben

8

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20 February 2020

language of work or name

English

0 references

publication date

17 December 2012

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20 February 2020

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20 February 2020

volume

121

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20 February 2020

issue

9

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20 February 2020

page(s)

1612-1621

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Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling

20 February 2020

cites work

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Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer

30 September 2017

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30 September 2017

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MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers

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E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction

30 September 2017

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30 September 2017

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30 September 2017

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Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug

30 September 2017

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CD8 T cell dysfunction during chronic viral infection.

30 September 2017

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Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

30 September 2017

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Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells

30 September 2017

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Central memory and effector memory T cell subsets: function, generation, and maintenance

30 September 2017

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Antigen-driven effector CD8 T cell function regulated by T-bet

30 September 2017

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Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

30 September 2017

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Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

30 September 2017

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A novel transcription factor, T-bet, directs Th1 lineage commitment

30 September 2017

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Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes

30 September 2017

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30 September 2017

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Interferon gamma inhibits apoptotic cell death in B cell chronic lymphocytic leukemia

30 September 2017

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A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection.

30 September 2017

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A shorter time to the first treatment may be predicted by the absolute number of regulatory T-cells in patients with Rai stage 0 chronic lymphocytic leukemia.

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20 September 2018

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Expansion of a CD8(+)PD-1(+) replicative senescence phenotype in early stage CLL patients is associated with inverted CD4:CD8 ratios and disease progression.

20 September 2018

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Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.

20 September 2018

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20 September 2018

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20 September 2018

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20 September 2018

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20 September 2018

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20 September 2018

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20 September 2018

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20 September 2018

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Expansion of CMV-specific CD8+CD45RA+CD27- T cells in B-cell chronic lymphocytic leukemia

20 September 2018

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Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals.

20 September 2018

1 reference

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Abnormal T lymphocyte subpopulations in patients with B cell chronic lymphocytic leukemia: an analysis by monoclonal antibodies

20 September 2018

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12 December 2020

Characterization of regulatory T cells in patients with B-cell chronic lymphocytic leukemia

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12 December 2020

Clinical significance of T-cells in chronic lymphocytic leukaemia

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12 December 2020

Tumor necrosis factor induces proliferation of neoplastic B cells from chronic lymphocytic leukemia

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12 December 2020

Peripheral blood lymphocyte subset shifts in patients with untreated hematological tumors: evidence for systemic activation of the T cell compartment

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12 December 2020

T-cell responses against chronic lymphocytic leukemia cells: implications for immunotherapy

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12 December 2020

The silent war against CMV in CLL

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12 December 2020

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

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12 December 2020

CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator

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12 December 2020

10.1182/BLOOD-2012-09-457531

Identifiers

DOI

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release_dh67zp5zybc5hlt4mfgj5szp2e

20 February 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/dh67zp5zybc5hlt4mfgj5szp2e

24 November 2022

mapped directly with Wikidata item

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20 February 2020

PubMed publication ID

23247726

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