Novel purine nucleoside analogues for T-cell-lineage acute lymphoblastic leukaemia and lymphoma (Q36654341)

15 August 2017

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title

Novel purine nucleoside analogues for T-cell-lineage acute lymphoblastic leukaemia and lymphoma (English)

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15 August 2017

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1

Farhad Ravandi

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15 August 2017

Varsha Gandhi

2

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PubMed ID

17107284

15 August 2017

language of work or name

English

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publication date

1 December 2006

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Expert Opinion on Investigational Drugs

15 August 2017

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15 August 2017

15

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15 August 2017

12

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15 August 2017

1601-1613

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The molecular pathology of primary immunodeficiencies

15 August 2017

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Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity

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1 reference

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Central nervous system dysfunction and erythrocyte guanosine triphosphate depletion in purine nucleoside phosphorylase deficiency

21 January 2018

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The metabolism of deoxyguanosine in mitochondria: a characterization of the phosphorylation process which occurs in intact mitochondria

21 January 2018

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Biochemical basis for the enhanced toxicity of deoxyribonucleosides toward malignant human T cell lines

21 January 2018

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Purinogenic immunodeficiency diseases: selective toxicity of deoxyribonucleosides for T cells

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Purine nucleoside phosphorylases: properties, functions, and clinical aspects

21 January 2018

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Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir

21 January 2018

1 reference

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Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts

21 January 2018

1 reference

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Comparative in vitro and in vivo activities of two 9-deazaguanine analog inhibitors of purine nucleoside phosphorylase, CI-972 and PD 141955

21 January 2018

1 reference

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Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs

21 January 2018

1 reference

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One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase

21 January 2018

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Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents

21 January 2018

1 reference

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Transition states and inhibitors of the purine nucleoside phosphorylase family

21 January 2018

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Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes

21 January 2018

1 reference

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Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)--a novel potent and orally active immunosuppressive agent

21 January 2018

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Intravenous and oral pharmacokinetic study of BCX-1777, a novel purine nucleoside phosphorylase transition-state inhibitor. In vivo effects on blood 2′-deoxyguanosine in primates

21 January 2018

1 reference

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Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor--BCX-1777.

21 January 2018

1 reference

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Specific cytotoxicity of arabinosylguanine toward cultured T lymphoblasts

21 January 2018

1 reference

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Phosphorylation of arabinosyl guanine by a mitochondrial enzyme of bovine liver

21 January 2018

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Partial purification and characterization of deoxyguanosine kinase from pig skin

21 January 2018

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Mechanisms for T-cell selective cytotoxicity of arabinosylguanine

21 January 2018

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Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies

21 January 2018

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Nelarabine: a nucleoside analog with efficacy in T-cell and other leukemias

21 January 2018

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Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: a report from the Children's Oncology Group

21 January 2018

1 reference

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Guanine arabinoside as a bone marrow-purging agent

21 January 2018

1 reference

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10.1517/13543784.15.12.1601

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17107284