Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates (Q36656036)

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scientific article published on January 1, 1992

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English	Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates	scientific article published on January 1, 1992

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scholarly article

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Europe PubMed Central

15 August 2017

Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates (English)

1 reference

Europe PubMed Central

15 August 2017

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10.1128/JVI.66.1.235-243.1992

https://api.crossref.org/works/10.1128/JVI.66.1.235-243.1992

10 November 2022

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10.1128/JVI.66.1.235-243.1992

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10 November 2022

author name string

J. P. Moore

1

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J. A. McKeating

2

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10 November 2022

Y. X. Huang

3

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A. Ashkenazi

4

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D. D. Ho

5

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1 January 1992

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15 August 2017

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9

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full work available at URL

http://jvi.asm.org/cgi/content/abstract/66/1/235

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1727487/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1727487/pdf/?tool=EBI

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https://europepmc.org/articles/PMC238280

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https://europepmc.org/articles/PMC238280?pdf=render

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https://journals.asm.org/doi/pdf/10.1128/jvi.66.1.235-243.1992

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10.1128/JVI.66.1.235-243.1992

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10 November 2022

Journal of Virology

1 reference

Europe PubMed Central

15 August 2017

66

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Europe PubMed Central

15 August 2017

1

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Europe PubMed Central

15 August 2017

235-243

1 reference

Europe PubMed Central

15 August 2017

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

1 reference

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The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1 reference

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T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

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Human immunodeficiency virus infection of CD4-bearing cells occurs by a pH-independent mechanism

1 reference

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A soluble form of CD4 (T4) protein inhibits AIDS virus infection

1 reference

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30 September 2017

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1 reference

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30 September 2017

Human T-cell lymphotropic virus IIIB glycoprotein (gp120) bound to CD4 determinants on normal lymphocytes and expressed by infected cells serves as target for immune attack

1 reference

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30 September 2017

Binding of HTLV-III/LAV to T4+ T cells by a complex of the 110K viral protein and the T4 molecule

1 reference

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30 September 2017

Inhibition of CD4+ T cell function by the HIV envelope protein, gp120

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30 September 2017

Lymphocyte activation by HIV-1 envelope glycoprotein

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30 September 2017

HIV infection is blocked in vitro by recombinant soluble CD4.

1 reference

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30 September 2017

Quantifying the infectivity of human immunodeficiency virus

1 reference

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30 September 2017

Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4.

1 reference

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30 September 2017

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1 reference

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30 September 2017

Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: prediction of antigenic epitopes in conserved and variable regions.

1 reference

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30 September 2017

Binding of the human retrovirus HTLV-III/LAV/ARV/HIV to the CD4 (T4) molecule: conformation dependence, epitope mapping, antibody inhibition, and potential for idiotypic mimicry

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30 September 2017

Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis

1 reference

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30 September 2017

CD4 immunoadhesin, but not recombinant soluble CD4, blocks syncytium formation by human immunodeficiency virus type 2-infected lymphoid cells

1 reference

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30 September 2017

High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates

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30 September 2017

Relative inefficiency of soluble recombinant CD4 for inhibition of infection by monocyte-tropic HIV in monocytes and T cells.

1 reference

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30 September 2017

Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding

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30 September 2017

Human immunodeficiency virus structure: implications for antiviral design.

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30 September 2017

Binding of soluble CD4 proteins to human immunodeficiency virus type 1 and infected cells induces release of envelope glycoprotein gp120.

1 reference

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30 September 2017

Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein

1 reference

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30 September 2017

Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virions: gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralization by soluble CD4.

1 reference

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30 September 2017

Differential loss of envelope glycoprotein gp120 from virions of human immunodeficiency virus type 1 isolates: effects on infectivity and neutralization

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30 September 2017

Resistance of primary isolates of human immunodeficiency virus type 1 to soluble CD4 is independent of CD4-rgp120 binding affinity

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30 September 2017

Recombinant CD4-selected human immunodeficiency virus type 1 variants with reduced gp120 affinity for CD4 and increased cell fusion capacity

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30 September 2017

Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding

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30 September 2017

Soluble CD4 enhances simian immunodeficiency virus SIVagm infection

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30 September 2017

Molecular targets for AIDS therapy

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Blocking of human immunodeficiency virus infection depends on cell density and viral stock age

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30 September 2017

pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane

1 reference

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28 June 2018

Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: effect of HIV sequence variation and a mechanism for CD4+ cell depletion

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28 June 2018

Soluble CD4 molecules neutralize human immunodeficiency virus type 1.

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28 June 2018

Highly efficient neutralization of HIV with recombinant CD4-immunoglobulin molecules.

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Designing CD4 immunoadhesins for AIDS therapy

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28 June 2018

HIV requires multiple gp120 molecules for CD4-mediated infection

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Enhancement of SIV infection with soluble receptor molecules

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The safety and pharmacokinetics of recombinant soluble CD4 (rCD4) in subjects with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. A phase 1 study.

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Recombinant soluble CD4 therapy in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. A phase I-II escalating dosage trial

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Dissociation of gp120 from HIV-1 virions induced by soluble CD4.

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28 June 2018

The human immunodeficiency virus type 1 envelope glycoprotein precursor acquires aberrant intermolecular disulfide bonds that may prevent normal proteolytic processing

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Characterization of recombinant gp120 and gp160 from HIV-1: binding to monoclonal antibodies and soluble CD4.

1 reference

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Biological properties of a CD4 immunoadhesin

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Receptor-mediated activation of immunodeficiency viruses in viral fusion

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Prevention of HIV-1 IIIB infection in chimpanzees by CD4 immunoadhesin

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Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by simian immunodeficiency virus

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HTLV-III large envelope protein (gp120) suppresses PHA-induced lymphocyte blastogenesis.

1 reference

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28 June 2018

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1 reference

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28 June 2018

Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells.

1 reference

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27 July 2018

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1727487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphometric analysis of recombinant soluble CD4-mediated release of the envelope glycoprotein gp120 from HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/1727487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory influences of envelope glycoproteins of HIV-1 on normal immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/1727487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human and simian immunodeficiency viruses HIV-1, HIV-2 and SIV interact with similar epitopes on their cellular receptor, the CD4 molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/1727487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergism between HIV gp120 and gp120-specific antibody in blocking human T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1727487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking of HIV-1 infectivity by a soluble, secreted form of the CD4 antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/1727487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simple methods for monitoring HIV-1 and HIV-2 gp120 binding to soluble CD4 by enzyme-linked immunosorbent assay: HIV-2 has a 25-fold lower affinity than HIV-1 for soluble CD4

1 reference

https://pubmed.ncbi.nlm.nih.gov/1727487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.66.1.235-243.1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1727487

10 November 2022

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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