Inhibition of Poly(ADP-Ribose) Polymerase Enhances Radiochemosensitivity in Cancers Proficient in DNA Double-Strand Break Repair (Q36656132)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23396107%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Inhibition of Poly(ADP-Ribose) Polymerase Enhances Radiochemosensitivity in Cancers Proficient in DNA Double-Strand Break Repair (English)

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23 February 2020

1

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23 February 2020

author name string

Gina Ferris

series ordinal

2

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23 February 2020

Charles Kunos

series ordinal

3

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23 February 2020

language of work or name

English

0 references

publication date

8 February 2013

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International Journal of Molecular Sciences

23 February 2020

published in

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23 February 2020

volume

14

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23 February 2020

issue

2

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23 February 2020

page(s)

3773-3785

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Creative Commons Attribution 4.0 International

23 February 2020

copyright license

start time

8 February 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Enhanced killing of cancer cells by poly(ADP-ribose) polymerase inhibitors and topoisomerase I inhibitors reflects poisoning of both enzymes.

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Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells

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Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair

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A novel poly(ADP-ribose) polymerase inhibitor, ABT-888, radiosensitizes malignant human cell lines under hypoxia

30 September 2017

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Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines

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Poly(ADP-ribose) polymerase-1 and ionizing radiation: sensor, signaller and therapeutic target

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Nicotinamide mononucleotide activation of a new DNA-dependent polyadenylic acid synthesizing nuclear enzyme

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Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog

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Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

30 September 2017

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Poly(ADP-ribose) polymerase, a major determinant of early cell response to ionizing radiation

30 September 2017

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Potentiation of temozolomide and topotecan growth inhibition and cytotoxicity by novel poly(adenosine diphosphoribose) polymerase inhibitors in a panel of human tumor cell lines.

30 September 2017

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DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III.

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30 September 2017

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23396107

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/IJMS14023773

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23396107%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

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23 February 2020

PubMed publication ID

23396107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23396107%20AND%20SRC:MED&resulttype=core&format=json