Expression of mutant eukaryotic initiation factor 2 alpha subunit (eIF-2 alpha) reduces inhibition of guanine nucleotide exchange activity of eIF-2B mediated by eIF-2 alpha phosphorylation (Q36656720)

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scientific article published on July 1994

Language	Label	Description	Also known as
English	Expression of mutant eukaryotic initiation factor 2 alpha subunit (eIF-2 alpha) reduces inhibition of guanine nucleotide exchange activity of eIF-2B mediated by eIF-2 alpha phosphorylation	scientific article published on July 1994

Statements

scholarly article

1 reference

Europe PubMed Central

15 August 2017

Expression of mutant eukaryotic initiation factor 2 alpha subunit (eIF-2 alpha) reduces inhibition of guanine nucleotide exchange activity of eIF-2B mediated by eIF-2 alpha phosphorylation (English)

1 reference

Europe PubMed Central

15 August 2017

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

K V Ramaiah

1

1 reference

Europe PubMed Central

15 August 2017

M V Davies

2

1 reference

Europe PubMed Central

15 August 2017

J J Chen

3

1 reference

Europe PubMed Central

15 August 2017

R J Kaufman

4

1 reference

Europe PubMed Central

15 August 2017

language of work or name

0 references

publication date

1 July 1994

1 reference

Europe PubMed Central

15 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

15 August 2017

14

1 reference

Europe PubMed Central

15 August 2017

7

1 reference

Europe PubMed Central

15 August 2017

4546-4553

1 reference

Europe PubMed Central

15 August 2017

Mutations in the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2 alpha) that overcome the inhibitory effect of eIF-2 alpha phosphorylation on translation initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

30 September 2017

Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

30 September 2017

The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans

1 reference

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30 September 2017

Regulation of protein synthesis by phosphorylation of eukaryotic initiation factor 2 alpha in intact reticulocytes and reticulocyte lysates

1 reference

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30 September 2017

Mode of action of the heme-controlled translational inhibitor: relationship of eukaryotic initiation factor 2-stimulating protein to translation restoring factor

1 reference

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Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

1 reference

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30 September 2017

Distribution of reversing factor in reticulocyte lysates during active protein synthesis and on inhibition by heme deprivation or double-stranded RNA.

1 reference

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30 September 2017

Effect of phosphorylation of the alpha-subunit of eukaryotic initiation factor 2 on the function of reversing factor in the initiation of protein synthesis

1 reference

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Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter

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Phosphorylation of the guanine nucleotide exchange factor from rabbit reticulocytes regulates its activity in polypeptide chain initiation

1 reference

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30 September 2017

The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2

1 reference

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30 September 2017

Generation of a mutant form of protein synthesis initiation factor eIF-2 lacking the site of phosphorylation by eIF-2 kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

30 September 2017

Protein synthesis and protein phosphorylation during heat stress, recovery, and adaptation

1 reference

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30 September 2017

The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs

1 reference

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30 September 2017

Complementation of adenovirus virus-associated RNA I gene deletion by expression of a mutant eukaryotic translation initiation factor

1 reference

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30 September 2017

Translational control in mammalian cells

1 reference

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30 September 2017

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1 reference

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

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Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus

1 reference

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30 September 2017

Mechanism and regulation of eukaryotic protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

30 September 2017

Correlation between the distribution of the reversing factor and eukaryotic initiation factor 2 in heme-deficient or double-stranded RNA-inhibited reticulocyte lysates

1 reference

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Poliovirus replicase stimulation by terminal uridylyl transferase

1 reference

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30 September 2017

Inhibition of HeLa cell protein synthesis under heat shock conditions in the absence of initiation factor eIF-2 alpha phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

28 June 2018

Role of reversing factor in the inhibition of protein synthesis initiation by oxidized glutathione

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

28 June 2018

Selection and coamplification of heterologous genes in mammalian cells

1 reference

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28 June 2018

Regulation of protein synthesis in Swiss 3T3 fibroblasts. Rapid activation of the guanine-nucleotide-exchange factor by insulin and growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

28 June 2018

Phosphorylation of eukaryotic initiation factor (eIF) 2 alpha and inhibition of eIF-2B in GH3 pituitary cells by perturbants of early protein processing that induce GRP78

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

28 June 2018

Stimulation of protein synthesis in COS cells transfected with variants of the alpha-subunit of initiation factor eIF-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

28 June 2018

Purification and Characterization of a Protein Factor that Reverses the Inhibition of Protein Synthesis by the Heme-Regulated Translational Inhibitor in Rabbit Reticulocyte Lysates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

28 June 2018

Expression of a phosphorylation-resistant eukaryotic initiation factor 2 alpha-subunit mitigates heat shock inhibition of protein synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

20 September 2018

Phosphorylation inhibits guanine nucleotide exchange on eukaryotic initiation factor 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=358826

20 September 2018

Disulfide bond formation in the regulation of eIF-2 alpha kinase by heme

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of the eukaryotic initiation factor 2-eukaryotic initiation factor 2B complex and characterization of its guanine nucleotide exchange activity during protein synthesis initiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A GDP/GTP exchange factor essential for eukaryotic initiation factor 2 cycling in Ehrlich ascites tumor cells and its regulation by eukaryotic initiation factor 2 phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulation of initiation of protein synthesis by phosphorylation of eIF-2(alpha) and the role of reversing factor in the recycling of eIF-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2B or not 2B: regulation of the catalytic utilization of eIF-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock-induced translational alterations in HeLa cells. Initiation factor modifications and the inhibition of translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of hemin-regulated initiation factor-2 kinase in heat-shocked HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NH2-terminal sequence of the alpha and gamma subunits of eukaryotic initiation factor 2 and the phosphorylation site for the heme-regulated eIF-2 alpha kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and regulation of eukaryotic initiation factor eIF-2. Sequence of the site in the alpha subunit phosphorylated by the haem-controlled repressor and by the double-stranded RNA-activated inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of eukaryotic initiation factor 2 during physiological stresses which affect protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological stresses inhibit guanine-nucleotide-exchange factor in Ehrlich cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of the inhibition of protein synthesis by vasopressin in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/8007958

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.14.7.4546

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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