Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis (Q36664243)

15 August 2017

Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis (English)

1 reference

15 August 2017

8

Kimiko Murakami-Murofushi

1 reference

15 August 2017

Mari Gotoh

1

1 reference

15 August 2017

Yuko Fujiwara

2

1 reference

15 August 2017

Junming Yue

3

1 reference

15 August 2017

Jianxiong Liu

4

1 reference

15 August 2017

SueChin Lee

5

1 reference

15 August 2017

James Fells

6

1 reference

15 August 2017

Ayako Uchiyama

7

1 reference

15 August 2017

Stephen Kennel

9

1 reference

15 August 2017

Jonathan Wall

10

1 reference

15 August 2017

Renukadevi Patil

11

1 reference

15 August 2017

Renuka Gupte

12

1 reference

15 August 2017

Louisa Balazs

13

1 reference

15 August 2017

Duane D Miller

14

1 reference

15 August 2017

Gabor J Tigyi

15

1 reference

15 August 2017

1 February 2012

1 reference

Biochemical Society Transactions

15 August 2017

1 reference

15 August 2017

40

1 reference

15 August 2017

1

1 reference

15 August 2017

31-36

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Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Specific increase in serum autotaxin activity in patients with pancreatic cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Structural basis of substrate discrimination and integrin binding by autotaxin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Lysophosphatidic acid augments human hepatocellular carcinoma cell invasion through LPA1 receptor and MMP-9 expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Lysophosphatidic acid inhibits CC chemokine ligand 5/RANTES production by blocking IRF-1-mediated gene transcription in human bronchial epithelial cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Aiming drug discovery at lysophosphatidic acid targets

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Phospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Inhibition of tumor growth and angiogenesis by a lysophosphatidic acid antagonist in an engineered three-dimensional lung cancer xenograft model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Autotaxin delays apoptosis induced by carboplatin in ovarian cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Lysophosphatidic acid 2 receptor-mediated supramolecular complex formation regulates its antiapoptotic effect

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Autotaxin protects MCF-7 breast cancer and MDA-MB-435 melanoma cells against Taxol-induced apoptosis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Role of LPA4/p2y9/GPR23 in negative regulation of cell motility

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Positive feedback between vascular endothelial growth factor-A and autotaxin in ovarian cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

LPA-induced epithelial ovarian cancer (EOC) in vitro invasion and migration are mediated by VEGF receptor-2 (VEGF-R2).

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

The emerging role of lysophosphatidic acid in cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Identification of genes associated with metastasis of mammary carcinoma in metastatic versus non-metastatic cell lines.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Expression of autotaxin, an ectoenzyme that produces lysophosphatidic acid, in human placenta.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid.

28 June 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110608

Plasma lysophosphatidic acid concentration and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110608

Autotaxin as a novel serum marker of liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110608

Low-density lipoprotein-cholesterol/high-density lipoprotein-cholesterol ratio predicts lipid-rich coronary plaque in patients with coronary artery disease--integrated-backscatter intravascular ultrasound study

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110608

Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110608

Expression of sphingosine-1-phosphate receptors and lysophosphatidic acid receptors on cultured and xenografted human colon, breast, melanoma, and lung tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110608

Plasminogen fragmentation and increased production of extracellular matrix-degrading proteinases are associated with serous epithelial ovarian cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110608

Rapid clearance of the circulating metastatic factor autotaxin by the scavenger receptors of liver sinusoidal endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110608

Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110608

Lysophospholipids are potential biomarkers of ovarian cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590848

Correlations between c-myc gene copy-number and clinicopathological parameters of ovarian tumours

20 September 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110608

Lysophosphatidic acid induces urokinase secretion by ovarian cancer cells

21 January 2018

1 reference

12 December 2020

Lysophosphatidic acid as a potential biomarker for ovarian and other gynecologic cancers

1 reference

12 December 2020

Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C

1 reference

12 December 2020

Suppression of lysophosphatidic acid and lysophosphatidylcholine formation in the plasma in vitro: proposal of a plasma sample preparation method for laboratory testing of these lipids

1 reference

12 December 2020

Hepatoma cell migration through a mesothelial cell monolayer is inhibited by cyclic AMP-elevating agents via a Rho-dependent pathway

1 reference

12 December 2020

Identifiers

DOI

10.1042/BST20110608

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

22260662

1 reference