Risks of phase I research with healthy participants: A systematic review (Q36665273)

15 August 2017

Risks of phase I research with healthy participants: A systematic review (English)

1 reference

15 August 2017

1 reference

3

Ezekiel Emanuel

1 reference

15 August 2017

4

David Wendler

1 reference

15 August 2017

2

Annette Rid

1 reference

15 August 2017

Rebecca A Johnson

1

1 reference

PMCID

4783291

15 August 2017

language of work or name

1 reference

8 September 2015

1 reference

15 August 2017

1 reference

15 August 2017

13

1 reference

15 August 2017

2

1 reference

15 August 2017

149-160

1 reference

Quantifying the risks of non-oncology phase I research in healthy volunteers: meta-analysis of phase I studies

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

All trials must be registered and the results published

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

The elephant in the (board) room: the role of contract research organizations in international clinical research

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Outcome reporting among drug trials registered in ClinicalTrials.gov

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Trends in risks associated with new drug development: success rates for investigational drugs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Trial publication after registration in ClinicalTrials.Gov: a cross-sectional analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

The need for improved access to FDA reviews

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Inadequate dissemination of phase I trials: a retrospective cohort study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Reporting bias in drug trials submitted to the Food and Drug Administration: review of publication and presentation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Issues in the registration of clinical trials

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Balancing justice and autonomy in clinical research with healthy volunteers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Establishing risk of human experimentation with drugs: lessons from TGN1412.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Strategies to minimize risks and exploitation in phase one trials on healthy subjects

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Scientific research is a moral duty

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

A taxpayer-funded clinical trials registry and results database

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

The hexamethonium asthma study and the death of a normal volunteer in research

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Paying people to participate in research: why not? A response to Wilkinson and Moore

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Healthy volunteer studies in Great Britain: the results of a survey into 12 months activity in this field

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Accessibility of trial reports for drugs stalling in development: a systematic assessment of registered trials

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

After the London tragedy, is it still possible to consider Phase I is safe?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Medical research on normal volunteers

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Access to information and the right to health: the human rights case for clinical trials transparency.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Rethinking research ethics.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783291

Justice for the Professional Guinea Pig

20 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1177%2F1740774515602868

Adverse events in phase-I studies: a report in 1015 healthy volunteers

21 January 2018

1 reference

12 December 2020

Adverse events in volunteers participating in phase I clinical trials: a single-center five-year survey in 1,559 subjects

1 reference

12 December 2020

Compensation for injured research subjects

1 reference

12 December 2020

TeGenero fiasco prompts regulatory rethink

1 reference

12 December 2020

Progress and deficiencies in the registration of clinical trials

1 reference

12 December 2020

Exploiting a research underclass in phase 1 clinical trials

1 reference

12 December 2020

Commercializing clinical trials--risks and benefits of the CRO boom

1 reference

12 December 2020

Identifiers

DOI

10.1177/1740774515602868

1 reference

15 August 2017

1 reference

15 August 2017

1 reference

PMCID

4783291