Immunopathogenesis of hepatitis B virus infection (Q36666336)

15 August 2017

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title

Immunopathogenesis of hepatitis B virus infection (English)

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15 August 2017

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Sharon R Lewin

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author name string

J Judy Chang

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1

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15 August 2017

28 November 2006

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Immunology & Cell Biology

15 August 2017

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15 August 2017

85

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15 August 2017

16-23

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15 August 2017

1

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Geographic and species association of hepatitis B virus genotypes in non-human primates.

15 August 2017

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Hepatitis B virus infection--natural history and clinical consequences

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Predominant T-helper 1 cytokine profile of hepatitis B virus nucleocapsid-specific T cells in acute self-limited hepatitis B.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Toll-like receptor signaling inhibits hepatitis B virus replication in vivo.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Cutting edge: Inhibition of hepatitis B virus replication by activated NK T cells does not require inflammatory cell recruitment to the liver

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

The role of intrahepatic immune effector cells in inflammatory liver injury and viral control during chronic hepatitis B infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Dynamics of hepatitis B virus clearance in chimpanzees

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Innate sensing of viruses by toll-like receptors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Activated intrahepatic antigen-presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Natural killer T cell activation inhibits hepatitis B virus replication in vivo.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Host-virus interactions during malaria infection in hepatitis B virus transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Long-lasting memory T cell responses following self-limited acute hepatitis B

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Cellular immune responses to the hepatitis B virus polymerase

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Tumor necrosis factor alpha inhibition of hepatitis B virus replication involves disruption of capsid Integrity through activation of NF-kappaB.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

T cell receptor usage of virus-specific CD8 cells and recognition of viral mutations during acute and persistent hepatitis B virus infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Analysis of intrahepatic HBV-specific cytotoxic T-cells during and after acute HBV infection in humans.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Hepatitis B virus immunopathogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Cytotoxic T-cell responses to the nucleocapsid proteins of HBV in chronic hepatitis. Evidence that antibody modulation may cause protracted infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Reduced hepatitis B virus (HBV)-specific CD4+ T-cell responses in human immunodeficiency virus type 1-HBV-coinfected individuals receiving HBV-active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: new perspectives for immune therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Hepatitis B virus-induced defect of monocyte-derived dendritic cells leads to impaired T helper type 1 response in vitro: mechanisms for viral immune escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Restoring function in exhausted CD8 T cells during chronic viral infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Expression of the interleukin-7 receptor alpha chain (CD127) on virus-specific CD8+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Oscillating CD8(+) T cell effector functions after antigen recognition in the liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

T regulatory cells in allergy: novel concepts in the pathogenesis, prevention, and treatment of allergic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with hepatitis B virus infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Increased hepatitis C virus (HCV)-specific CD4+CD25 + regulatory T lymphocytes and reduced HCV-specific CD4+ T cell response in HCV-infected patients with normal versus abnormal alanine aminotransferase levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Selective functional deficit in dendritic cell--T cell interaction is a crucial mechanism in chronic hepatitis B virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Reduced expression of toll-like receptor 2 on peripheral monocytes in patients with chronic hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Hepatitis B virus X protein: a multifunctional viral regulator

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Posttranscriptional clearance of hepatitis B virus RNA by cytotoxic T lymphocyte-activated hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Interleukin 12 suppresses autoantibody production by reversing helper T-cell phenotype in hepatitis B e antigen transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Interleukin-12 induction of Th1 cytokines is important for viral clearance in chronic hepatitis B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

The role of transplacental hepatitis B core antibody in the mother-to-infant transmission of hepatitis B virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Mutations in the basic core promotor and the precore region of hepatitis B virus and their selection in children with fulminant and chronic hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Hepatitis B virus mutants and fulminant hepatitis B: fitness plus phenotype

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Dynamics of alanine aminotransferase during hepatitis C virus treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Nondeletional T-cell receptor transgenic mice: model for the CD4(+) T-cell repertoire in chronic hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

The intrahepatic immune response during chronic hepatitis B infection can be monitored by the fine-needle aspiration biopsy technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Hepatitis B virus enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity by increasing TRAIL-R1/death receptor 4 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Expression of FasL and perforin/granzyme B mRNA in chronic hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Apoptosis mediated by the Fas system in the fulminant hepatitis by hepatitis B virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Intrahepatic CD8 T-lymphocytes and HBV core expression in relation to response to antiviral therapy for chronic hepatitis B patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Tracking the source of the hepatitis B virus-specific CD8 T cells during lamivudine treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

The impact of HBV-DNA fluctuations on virus-specific CD8+ T cells in HBeAg+ chronic hepatitis B patients treated with a steroid and lamivudine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

A randomized, controlled trial of combination therapy for chronic hepatitis B: comparing pegylated interferon-alpha2b and lamivudine with lamivudine alone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Intrahepatic CD8+ T-lymphocyte response is important for therapy-induced viral clearance in chronic hepatitis B infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Treatment with Peg-interferon alpha-2b for HBeAg-positive chronic hepatitis B: HBsAg loss is associated with HBV genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Immunology of hepatitis B virus and hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Incubation phase of acute hepatitis B in man: dynamic of cellular immune mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Different composition of intrahepatic lymphocytes in the immune-tolerance and immune-clearance phase of chronic hepatitis B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

Reduction in the circulating pDC1/pDC2 ratio and impaired function of ex vivo-generated DC1 in chronic hepatitis B infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

7 January 2021

Activation of class I major histocompatibility complex gene expression by hepatitis B virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

7 January 2021

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

7 January 2021

Evidence for a dynamic host-parasite relationship in e-negative hepatitis B carriers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

7 January 2021

In situ investigation of Fas/FasL expression in chronic hepatitis B infection and related liver diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100009

1 reference

7 January 2021

Identifiers

DOI

10.1038/SJ.ICB.7100009

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15 August 2017

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PubMed ID

17130898