Activation of T lymphocytes and the role of the adapter LAT. (Q36677953)

15 August 2017

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title

Activation of T lymphocytes and the role of the adapter LAT. (English)

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15 August 2017

Enrique Aguado

1

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PubMed ID

17157209

15 August 2017

Mario Martínez-Florensa

series ordinal

2

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PubMed ID

17157209

15 August 2017

Pedro Aparicio

series ordinal

3

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15 August 2017

10 October 2006

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15 August 2017

Transplant Immunology

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15 August 2017

17

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15 August 2017

1

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15 August 2017

23-26

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LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

15 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

Identification of the minimal tyrosine residues required for linker for activation of T cell function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

Essential role of LAT in T cell development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

LAT regulates gammadelta T cell homeostasis and differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

Induction of T helper type 2 immunity by a point mutation in the LAT adaptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

A LAT mutation that inhibits T cell development yet induces lymphoproliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

Negative feedback loop in T-cell activation through MAPK-catalyzed threonine phosphorylation of LAT.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

Cutting Edge: Localization of linker for activation of T cells to lipid rafts is not essential in T cell activation and development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

Impaired activation and localization of LAT in anergic T cells as a consequence of a selective palmitoylation defect.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIM.2006.09.013

10.1016/J.TRIM.2006.09.013

7 January 2021

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17157209