Glucose sensing by hypothalamic neurones and pancreatic islet cells: AMPle evidence for common mechanisms? (Q36678537)

15 August 2017

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title

Glucose sensing by hypothalamic neurones and pancreatic islet cells: AMPle evidence for common mechanisms? (English)

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15 August 2017

2

Guy A Rutter

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15 August 2017

Philip D Mountjoy

1

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15 August 2017

7 December 2006

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15 August 2017

Experimental Physiology

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15 August 2017

92

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15 August 2017

2

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15 August 2017

311-319

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Dynamic imaging of free cytosolic ATP concentration during fuel sensing by rat hypothalamic neurones: evidence for ATP-independent control of ATP-sensitive K(+) channels

15 August 2017

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

AMP-activated protein kinase plays a role in the control of food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Glucose-induced excitation of hypothalamic neurones is mediated by ATP-sensitive K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Physiological changes in glucose differentially modulate the excitability of hypothalamic melanin-concentrating hormone and orexin neurons in situ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

The anatomy of neuropeptide-Y-containing neurons in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Selective deletion of leptin receptor in neurons leads to obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

A new ATP-sensitive K+ channel-independent mechanism is involved in glucose-excited neurons of mouse arcuate nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

The effect of leptin on feeding-regulating neurons in the rat hypothalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Circumventricular organs: definition and role in the regulation of endocrine and autonomic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

The electrophysiology of feeding circuits

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Glucokinase is a critical regulator of ventromedial hypothalamic neuronal glucosensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus: Ca2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

D-glucose suppression of eating after intra-third ventricle infusion in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Regulation of blood glucose by hypothalamic pyruvate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Metabolic sensors: viewing glucosensing neurons from a broader perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Orexin a preferentially excites glucose-sensitive neurons in the lateral hypothalamus of the rat in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Cellular warriors at the battle of the bulge

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Glucose responding neurons in the nucleus tractus solitarius of the rat: In vitro study

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose-responsive neurons to regulate Ca 2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Lowering glucose concentrations increases cytosolic Ca2+ in orexin neurons of the rat lateral hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Glucose and osmosensitive neurones of the rat hypothalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Glucose Inhibition of the Glucose-sensitive Neurone in the Rat Lateral Hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic alpha-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Over-expression of AMP-activated protein kinase impairs pancreatic {beta}-cell function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Functional glucokinase isoforms are expressed in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Visualising insulin secretion. The Minkowski Lecture 2004.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

Hypothalamic orexin neurons regulate arousal according to energy balance in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036004

10.1113/EXPPHYSIOL.2006.036004

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17158178