Protein kinase C beta inhibition: A novel therapeutic strategy for diabetic microangiopathy (Q36679604)

15 August 2017

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title

Protein kinase C beta inhibition: A novel therapeutic strategy for diabetic microangiopathy (English)

1 reference

15 August 2017

Iskandar Idris

1

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PubMed ID

17160912

15 August 2017

Richard Donnelly

series ordinal

2

1 reference

PubMed ID

17160912

15 August 2017

language of work or name

English

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publication date

1 December 2006

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Diabetes and Vascular Disease Research

15 August 2017

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15 August 2017

3

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15 August 2017

172-178

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15 August 2017

3

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

15 August 2017

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Biochemistry and molecular cell biology of diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Advanced glycation end-products: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Oxidative stress and antioxidant treatment in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Protein kinase C and the development of diabetic vascular complications

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Hyperglycemia regulates hypoxia-inducible factor-1alpha protein stability and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Pathogenesis, prevention, and treatment of diabetic nephropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Thrombin-induced shape changes of cultured endothelial cells: metabolic and functional observations.

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Protein kinase C phosphorylates caldesmon77 and vimentin and enhances albumin permeability across cultured bovine pulmonary artery endothelial cell monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

PAF- and bradykinin-induced hyperpermeability of rat venules is independent of actin-myosin contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Vascular Endothelial Growth Factor in Diabetic Nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Protein kinase C activation and the development of diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Caldesmon is a cytoskeletal target for PKC in endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Enhanced expression of inducible nitric oxide synthase in murine macrophages and glomerular mesangial cells by elevated glucose levels: possible mediation via protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Vascular endothelial growth factor (VEGF)-induced retinal vascular permeability is mediated by intercellular adhesion molecule-1 (ICAM-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Protein kinase C activity is acutely regulated by plasma glucose concentration in human monocytes in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Abnormalities of retinal metabolism in diabetes or experimental galactosemia: V. Relationship between protein kinase C and ATPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: role of oxidants and protein kinase-C activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Inhibition of PKC beta by oral administration of ruboxistaurin is well tolerated and ameliorates diabetes-induced retinal hemodynamic abnormalities in patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Protein kinase C inhibition and diabetic retinopathy: a shot in the dark at translational research

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

Treatment of symptomatic diabetic peripheral neuropathy with the protein kinase C beta-inhibitor ruboxistaurin mesylate during a 1-year, randomized, placebo-controlled, double-blind clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

The effect of ruboxistaurin on nephropathy in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3132%2FDVDR.2006.026

21 January 2018

Identifiers

DOI

10.3132/DVDR.2006.026

1 reference

15 August 2017

1 reference

PubMed ID

17160912