Ribozyme technology for cancer gene target identification and validation (Q36680080)

15 August 2017

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title

Ribozyme technology for cancer gene target identification and validation (English)

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15 August 2017

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4

Flossie Wong-Staal

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15 August 2017

Qi-Xiang Li

1

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15 August 2017

Philip Tan

series ordinal

2

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15 August 2017

Ning Ke

series ordinal

3

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15 August 2017

publication date

1 January 2007

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Advances in Cancer Research

15 August 2017

published in

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15 August 2017

volume

96

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15 August 2017

page(s)

103-143

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Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Expression of the receptor protein tyrosine kinase myk-1/htk in normal and malignant mammary epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Ceramide-induced cell death is independent of the Fas/Fas ligand pathway and is prevented by Nur77 overexpression in A20 B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Enhanced expression and HIV-1 inhibition of chimeric tRNA(Lys3)-ribozymes under dual U6 snRNA and tRNA promoters

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Inhibition of CCR5-dependent HIV-1 infection by hairpin ribozyme gene therapy against CC-chemokine receptor 5.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Search for genes that suppress cancer metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Proapoptotic activity of ITM2B(s), a BH3-only protein induced upon IL-2-deprivation which interacts with Bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

ITM2BS regulates apoptosis by inducing loss of mitochondrial membrane potential

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

RNA catalytic properties of the minimum (-)sTRSV sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

'Hairpin' catalytic RNA model: evidence for helices and sequence requirement for substrate RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

A nude mouse model of human osteosarcoma lung metastases for evaluating new therapeutic strategies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Identification of genes by hybrid ribozymes that couple cleavage activity with the unwinding activity of an endogenous RNA helicase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Identification of genes that function in the TNF-alpha-mediated apoptotic pathway using randomized hybrid ribozyme libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

One-week 96-well soft agar growth assay for cancer target validation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Nuclear hormone receptor NR4A2 is involved in cell transformation and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

EphB ligand, ephrinB2, suppresses the VEGF- and angiopoietin 1-induced Ras/mitogen-activated protein kinase pathway in venous endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Significantly higher activity of a cytoplasmic hammerhead ribozyme than a corresponding nuclear counterpart: engineered tRNAs with an extended 3' end can be exported efficiently and specifically to the cytoplasm in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Efficient and specific ribozyme-mediated reduction of bovine alpha-lactalbumin expression in double transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

A novel functional genomics approach identifies mTERT as a suppressor of fibroblast transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Coexpression of ephrin-Bs and their receptors in colon carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Suppression of EGFRvIII-mediated proliferation and tumorigenesis of breast cancer cells by ribozyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

HeLa cells 50 years on: the good, the bad and the ugly

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Molecular cloning of a novel thyroid/steroid receptor superfamily gene from cultured rat neuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Rapid identification of efficient target cleavage sites using a hammerhead ribozyme library in an iterative manner

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Rapid determination and quantitation of the accessibility to native RNAs by antisense oligodeoxynucleotides in murine cell extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Oligonucleotide scanning of native mRNAs in extracts predicts intracellular ribozyme efficiency: ribozyme-mediated reduction of the murine DNA methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Detection of antisense and ribozyme accessible sites on native mRNAs: application to NCOA3 mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Multitarget ribozyme against the S1 genome segment of reovirus possesses novel cleavage activities and is more efficacious than its constituent mono-ribozymes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Receptor protein tyrosine kinase EphB4 is up-regulated in colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Expression of receptor tyrosine kinase HTK (hepatoma transmembrane kinase) and HTK ligand by human leukemia-lymphoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

A role of EphB4 receptor and its ligand, ephrin-B2, in erythropoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Identification of genes involved in cell invasion by using a library of randomized hybrid ribozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Identification of metastasis-related genes in a mouse model using a library of randomized ribozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Nur77 as a survival factor in tumor necrosis factor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Cancer genes and the pathways they control

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

RNA-protein hybrid ribozymes that efficiently cleave any mRNA independently of the structure of the target RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Identification and validation of a gene involved in anchorage-independent cell growth control using a library of randomized hairpin ribozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

A 96-well surrogate survival assay coupled with a special short interfering RNA vector for assessing cancer gene targets with enhanced signal/noise ratio and its utility in HTS for cancer therapeutic targets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

PHTS, a novel putative tumor suppressor, is involved in the transformation reversion of HeLaHF cells independently of the p53 pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2806%2996005-9

7 January 2021

10.1016/S0065-230X(06)96005-9

Identifiers

DOI

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15 August 2017

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