Retroviral insertion mutagenesis in mice as a comparative oncogenomics tool to identify disease genes in human leukemia (Q36681931)

15 August 2017

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title

Retroviral insertion mutagenesis in mice as a comparative oncogenomics tool to identify disease genes in human leukemia (English)

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15 August 2017

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Ivo P Touw

1

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PubMed ID

17164770

15 August 2017

Stefan J Erkeland

series ordinal

2

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15 August 2017

1 January 2007

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15 August 2017

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15 August 2017

15

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15 August 2017

1

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15 August 2017

13-19

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15 August 2017

Transformation by v-Myb

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

1 reference

7 January 2021

Transforming pathways activated by the v-Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Mutation of the core or adjacent LVb elements of the Moloney murine leukemia virus enhancer alters disease specificity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Nuclear factors that bind to the U3 region of two murine myeloid leukemia-inducing retroviruses, Cas-Br-E and Graffi

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Role of the LTR region between the enhancer and promoter in mink cell focus-forming murine leukemia virus pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Sequences between the enhancer and promoter in the long terminal repeat affect murine leukemia virus pathogenicity and replication in the thymus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Murine leukemia virus long terminal repeat sequences can enhance gene activity in a cell-type-specific manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Analysis of the disease potential of a recombinant retrovirus containing Friend murine leukemia virus sequences and a unique long terminal repeat from feline leukemia virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Differential disease restriction of Moloney and Friend murine leukemia viruses by the mouse Rmcf gene is governed by the viral long terminal repeat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Thymic dendritic cells are primary targets for the oncogenic virus SL3-3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Genome-based identification of cancer genes by proviral tagging in mouse retrovirus-induced T-cell lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Graffi murine leukemia virus: molecular cloning and characterization of the myeloid leukemia-inducing agent.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Large-scale identification of disease genes involved in acute myeloid leukemia

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Identification of a common ecotropic viral integration site, Evi-1, in the DNA of AKXD murine myeloid tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Murine T lymphomas in which the cellular myc oncogene has been activated by retroviral insertion.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Aberrant splicing events that are induced by proviral integration: implications for myb oncogene activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Mechanism of activation of the myb oncogene in myeloid leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

The common viral insertion site Evi12 is located in the 5'-noncoding region of Gnn, a novel gene with enhanced expression in two subclasses of human acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Sox4 cooperates with Evi1 in AKXD-23 myeloid tumors via transactivation of proviral LTR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Retroviral integration at the Evi-2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady-state Ras-GTP levels.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Evi-2, a common integration site involved in murine myeloid leukemogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Murine leukemia provirus-mediated activation of the Notch1 gene leads to induction of HES-1 in a mouse T lymphoma cell line, DL-3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Identification of Notch1 as a frequent target for provirus insertional mutagenesis in T-cell lymphomas induced by leukemogenic mutants of mouse mammary tumor virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Genetic heterogeneity in acute myeloid leukemia: maximizing information flow from MuLV mutagenesis studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Plag1 and Plagl2 are oncogenes that induce acute myeloid leukemia in cooperation with Cbfb-MYH11

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

MMTV-induced mutations in mouse mammary tumors: their potential relevance to human breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

1 reference

7 January 2021

High-throughput retroviral tagging to identify components of specific signaling pathways in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

New genes involved in cancer identified by retroviral tagging

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Large-scale identification of novel potential disease loci in mouse leukemia applying an improved strategy for cloning common virus integration sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

A rapid RT-PCR based method to isolate complementary DNA fragments flanking retrovirus integration sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Retroviral insertional mutagenesis: past, present and future

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Transcription start regions in the human genome are favored targets for MLV integration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Mutation and cancer: statistical study of retinoblastoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Tumour suppressor genes--one hit can be enough

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Tag, you're hit: retroviral insertions identify genes involved in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Retroviral insertion sites and cancer: fountain of all knowledge?

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

RTCGD: retroviral tagged cancer gene database

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Redefining the common insertion site

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Significance of murine retroviral mutagenesis for identification of disease genes in human acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Gene expression profiling of pediatric acute myelogenous leukemia

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Prognostically useful gene-expression profiles in acute myeloid leukemia.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Acute myeloid leukemia

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Hopping around the tumor genome: transposons for cancer gene discovery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300040

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300040

1 reference

15 August 2017

1 reference

PubMed ID

17164770