Considerations in the U.S. Environmental Protection Agency's testing approach for mutagenicity (Q36694547)

15 August 2017

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title

Considerations in the U.S. Environmental Protection Agency's testing approach for mutagenicity (English)

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15 August 2017

K. L. Dearfield

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1719404

7 November 2022

A. E. Auletta

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1719404

7 November 2022

M. C. Cimino

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1719404

7 November 2022

M. M. Moore

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1719404

7 November 2022

language of work or name

English

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publication date

1 November 1991

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full work available at URL

15 August 2017

25

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https://api.elsevier.com/content/article/PII:016511109190012K?httpAccept=text/xml

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https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

https://api.elsevier.com/content/article/PII:016511109190012K?httpAccept=text/plain

7 November 2022

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

7 November 2022

1 reference

15 August 2017

258

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15 August 2017

3

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15 August 2017

259-283

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Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells

15 August 2017

2

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The role of mammalian cell mutation assays in mutagenicity and carcinogenicity testing

7 November 2022

3

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Assessment of the potential germ cell mutagenicity of industrial and plant protection chemicals as part of an integrated study of genotoxicity in vitro and in vivo.

7 November 2022

4

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The prospects for a simplified and internationally harmonized approach to the detection of possible human carcinogens and mutagens

7 November 2022

5

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Carcinogen/mutagen screening strategies

7 November 2022

6

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP.

7 November 2022

7

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Analysis of the National Toxicology Program data on in vitro genetic toxicity tests using multivariate statistical methods

7 November 2022

10

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https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Utility of short-term tests for genetic toxicity in the aftermath of the NTP's analysis of 73 chemicals

7 November 2022

12

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Effect of pH shifts on the mutant frequency at the thymidine kinase locus in mouse lymphoma L5178Y TK+/- cells.

7 November 2022

13

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Specific gene mutations in L5178Y cells in culture.

7 November 2022

15

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https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Quantification of the genetic risk of environmental mutagens

7 November 2022

20

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https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The influence of the proportion of carcinogens on the cost-effectiveness of short-term tests.

7 November 2022

21

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

1984 survey of genetic toxicology testing in industry, government and academic laboratories.

7 November 2022

22

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The case for retention of mammalian cell mutagenicity assays

7 November 2022

23

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https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Effects of high osmotic strength on chromosome aberrations, sister-chromatid exchanges and DNA strand breaks, and the relation to toxicity

7 November 2022

24

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The prospects for a simplified and internationally harmonized approach to the detection of possible human carcinogens and mutagens

7 November 2022

25

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The prospects for a simplified and internationally harmonized approach to the detection of possible human carcinogens and mutagens

7 November 2022

26

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Genotoxicity of 1- and 2-nitropropane in the rat.

7 November 2022

27

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The induction of micronuclei as a measure of genotoxicity. A report of the U.S. Environmental Protection Agency Gene-Tox Program.

7 November 2022

29

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Comments and perspective on the EPA workshop on "The relationship between short-term test information and carcinogenicity"

7 November 2022

32

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The Salmonella typhimurium/mammalian microsomal assay. A report of the U.S. Environmental Protection Agency Gene-Tox Program

7 November 2022

33

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Cost-effectiveness of short-term tests for carcinogenicity.

7 November 2022

34

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Revised methods for the Salmonella mutagenicity test

7 November 2022

37

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency Gene-Tox Program

7 November 2022

38

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

In situ analysis of trifluorothymidine-resistant (TFTr) mutants of L5178Y/TK+/- mouse lymphoma cells

7 November 2022

40

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Analysis of trifluorothymidine-resistant (TFTr) mutants of L5178Y/TK+/- mouse lymphoma cells

7 November 2022

41

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Differential mutant quantitation at the mouse lymphoma tk and CHO hgprt loci

7 November 2022

42

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Mammalian in vivo and in vitro cytogenetic assays: a report of the U.S. EPA's gene-tox program

7 November 2022

43

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Quantitative estimation of the genetic risk associated with the induction of heritable translocations at low-dose exposure: ethylene oxide as an example

7 November 2022

44

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Chemical characterization of 465 known or suspected carcinogens and their correlation with mutagenic activity in the Salmonella typhimurium system

7 November 2022

45

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The mouse specific-locus test with agents other than radiations: interpretation of data and recommendations for future work

7 November 2022

46

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

A report of the U.S. Environmental Protection Agency Gene-Tox Program. Evaluation of mutagenicity assays for purposes of genetic risk assessment

7 November 2022

47

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Assay-specific genotoxicity of N-nitrosodibenzylamine to the rat liver in vivo.

7 November 2022

48

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Induced skeletal mutations

7 November 2022

49

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https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The genetic toxicity of human carcinogens and its implications

7 November 2022

50

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays.

7 November 2022

52

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Ionizing radiation: Levels and effects

7 November 2022

53

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

Mouse lymphoma L5178Y thymidine kinase locus assay of 50 compounds

7 November 2022

65

1 reference

https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

The GENE-TOX Program: genetic activity evaluation

7 November 2022

66

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https://api.crossref.org/works/10.1016/0165-1110(91)90012-K

7 November 2022

Identifiers

1 reference

15 August 2017

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