Recombinant human adenoviruses containing hybrid adenovirus type 5 (Ad5)/Ad12 E1A genes: characterization of hybrid E1A proteins and analysis of transforming activity and host range (Q36698767)

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scientific article published on July 1, 1992

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English	Recombinant human adenoviruses containing hybrid adenovirus type 5 (Ad5)/Ad12 E1A genes: characterization of hybrid E1A proteins and analysis of transforming activity and host range	scientific article published on July 1, 1992

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scholarly article

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Europe PubMed Central

PMC publication ID

15 August 2017

Recombinant human adenoviruses containing hybrid adenovirus type 5 (Ad5)/Ad12 E1A genes: characterization of hybrid E1A proteins and analysis of transforming activity and host range (English)

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Europe PubMed Central

PMC publication ID

15 August 2017

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author name string

T. Jelinek

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1534849

6 October 2022

F. L. Graham

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1534849

6 October 2022

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publication date

1 July 1992

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15 August 2017

full work available at URL

http://jvi.asm.org/cgi/content/abstract/66/7/4117

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1534849

6 October 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1534849/?tool=EBI

online access status

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1534849

6 October 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1534849/pdf/?tool=EBI

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1534849

6 October 2022

https://europepmc.org/articles/PMC241214

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Europe PubMed Central

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1534849

6 October 2022

https://europepmc.org/articles/PMC241214?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1534849

6 October 2022

Journal of Virology

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Europe PubMed Central

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15 August 2017

66

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Europe PubMed Central

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15 August 2017

7

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Europe PubMed Central

PMC publication ID

15 August 2017

4117-4125

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Complementation of adenovirus type 5 host range mutants by adenovirus type 12 in coinfected HeLa and BHK-21 cells

1 reference

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Deletion and insertion mutations in early region 1a of type 5 adenovirus that produce cold-sensitive or defective phenotypes for transformation.

1 reference

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Formation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coli

1 reference

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A new technique for the assay of infectivity of human adenovirus 5 DNA

1 reference

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30 September 2017

E1a regions of the human adenoviruses and of the highly oncogenic simian adenovirus 7 are closely related

1 reference

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30 September 2017

Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products

1 reference

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30 September 2017

Transformation by human adenoviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=241214

30 September 2017

Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome

1 reference

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Electroporation for the efficient transfection of mammalian cells with DNA.

1 reference

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30 September 2017

Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes

1 reference

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Structural genes encoding the thermophilic alpha-amylases of Bacillus stearothermophilus and Bacillus licheniformis

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Mapping of cellular protein-binding sites on the products of early-region 1A of human adenovirus type 5.

1 reference

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30 September 2017

The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation

1 reference

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30 September 2017

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1 reference

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30 September 2017

Two regions of the adenovirus early region 1A proteins are required for transformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=241214

30 September 2017

Multiple functional domains in the adenovirus E1A gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=241214

30 September 2017

An insertion mutation in the adenovirus type 12 early region 1A 13S mRNA unique region.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=241214

30 September 2017

When the products of oncogenes and anti-oncogenes meet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=241214

30 September 2017

Adenovirus E1A protein paradigm viral transactivator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=241214

30 September 2017

Cellular targets for transformation by the adenovirus E1A proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=241214

30 September 2017

Association of adenovirus early-region 1A proteins with cellular polypeptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=241214

30 September 2017

Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=241214

30 September 2017

The efficiency of adenovirus transformation of rodent cells is inversely related to the rate of viral E1A gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=241214

30 September 2017

Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein

1 reference

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30 September 2017

Interaction between human cyclin A and adenovirus E1A-associated p107 protein

1 reference

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30 September 2017

Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins

1 reference

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30 September 2017

Complementation of human adenovirus type 5 ts mutants by human adenovirus type 12

1 reference

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30 September 2017

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1 reference

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30 September 2017

Functions of adenovirus E1A.

1 reference

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30 September 2017

Mutational analysis of the adenovirus E1a gene: the role of transcriptional regulation in transformation

1 reference

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Binding of the Rb1 protein to E1A products is required for adenovirus transformation

1 reference

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Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1 reference

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The first exon of region E1a genes of adenoviruses 5 and 12 encodes a separate functional protein domain

1 reference

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Inhibition of protein synthesis enhances transformation of primary cells by viral DNA.

1 reference

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Adenovirus type 5 and adenovirus type 12 recombinant viruses containing heterologous E1 genes are viable, transform rat cells, but are not tumorigenic in rats

1 reference

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Use of deletion and point mutants spanning the coding region of the adenovirus 5 E1A gene to define a domain that is essential for transcriptional activation

1 reference

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Host range mutants of adenovirus type 12 E1 defective for lytic infection, transformation, and oncogenicity.

1 reference

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Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides.

1 reference

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Sequences in E1A proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen.

1 reference

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1 reference

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1 reference

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Effects of Ad5 E1A mutant viruses on the cell cycle in relation to the binding of cellular proteins including the retinoblastoma protein and cyclin A

1 reference

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Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses

1 reference

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Incomplete transformation of rat cells by a small fragment of adenovirus 12 DNA

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Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA.

1 reference

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Structure and gene organization in the transforming Hind III-G fragment of Ad12

1 reference

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An adenovirus E1a protein region required for transformation and transcriptional repression

1 reference

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Potential metal-binding domains in nucleic acid binding proteins

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Isolation of type 5 adenovirus mutants with a cold-sensitive host range phenotype: genetic evidence of an adenovirus transformation maintenance function

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534849

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Comparison of nucleotide sequences of the early E1a regions for subgroups A, B and C of human adenoviruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534849

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based on heuristic

inferred from PubMed ID database lookup

Structure of the adenovirus 2 early mRNAs

1 reference

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A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5

1 reference

https://pubmed.ncbi.nlm.nih.gov/1534849

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An N-terminal region of adenovirus E1a essential for cell transformation and induction of an epithelial cell growth factor

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.66.7.4117-4125.1992

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1534849

6 October 2022

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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