Human pancreatic digestive enzymes (Q36700204)

15 August 2017

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title

Human pancreatic digestive enzymes (English)

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15 August 2017

1

David C Whitcomb

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15 August 2017

Mark E Lowe

2

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15 August 2017

5 January 2007

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Digestive Diseases and Sciences

15 August 2017

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15 August 2017

52

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15 August 2017

1

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15 August 2017

1-17

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https://scigraph.springernature.com/pub.10.1007/s10620-006-9589-z

15 August 2017

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cites work

Caldecrin is a novel-type serine protease expressed in pancreas, but its homologue, elastase IV, is an artifact during cloning derived from caldecrin gene

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Processing of vegetable-borne carotenoids in the human stomach and duodenum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Molecular cloning of a human gastric lipase and expression of the enzyme in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Gastric lipases: biochemical and physiological studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Importance of human gastric lipase for intestinal lipolysis: an in vitro study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Human pancreatic lipase: A glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Pancreatic lipase-related protein 2 but not classical pancreatic lipase hydrolyzes galactolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Characterization of pancreatic lipase-related protein 2 isolated from human pancreatic juice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Bile salt-dependent lipase: its pathophysiological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Pancreatic phospholipase A2: isolation of the human gene and cDNAs from porcine pancreas and human lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Preparation and some properties of human pancreatic amylase including a comparison with human parotid amylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

The determination of subsite binding energies of porcine pancreatic alpha-amylase by comparing hydrolytic activity towards substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Role of parotid amylase in starch digestion in the gastro-intestinal tracts of diabetic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-006-9589-Z

Pancreatic lipase-related protein 1 (PLRP1) is present in the pancreatic juice of several species

21 January 2018

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12 December 2020

Porcine-pancreatic alpha amylase hydrolysis of substrates containing 6-deoxy-D-glucose and 6-deoxy-6-fluoro-D-glucose and the specificity of subsite binding

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12 December 2020

The folding of pancreatic elastase: independent domain refolding and inter-domain interaction

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12 December 2020

Carboxyl ester lipase activity in milk prevents fat-derived intestinal injury in neonatal mice

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12 December 2020

Structure of human milk bile salt activated lipase

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12 December 2020

Mechanisms of disease: Advances in understanding the mechanisms leading to chronic pancreatitis

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12 December 2020

Effects of chronic alcohol abuse on exocrine pancreatic secretion in man

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12 December 2020

Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen

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12 December 2020

Action of human pancreatic and salivary α-amylases on maltooligosaccharides: Evaluation of kinetic parameters

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12 December 2020

Structure and evolution of the lipase superfamily

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12 December 2020

Human milk lipases. II. Bile salt-stimulated lipase

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12 December 2020

cDNA cloning of carboxyl ester lipase from human pancreas reveals a unique proline-rich repeat unit

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12 December 2020

Isolated pancreatic amylase deficiency: probable error in maturation

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12 December 2020

Assessment of phospholipid malabsorption by quantification of fecal phospholipid

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12 December 2020

Purification and Characterization of Chicken Pepsinogen and Chicken Pepsin

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12 December 2020

Fat digestion in very low-birth-weight infants: effect of addition of human milk to low-birth-weight formula

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12 December 2020

The ELISA fecal elastase-1 polyclonal assay reacts with different antigens than those of the monoclonal assay

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12 December 2020

Identification and expression of the cDNA-encoding human mesotrypsin(ogen), an isoform of trypsin with inhibitor resistance

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12 December 2020

Early trypsinogen activation in acute pancreatitis.

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12 December 2020

Protease-activated receptor 2 exerts local protection and mediates some systemic complications in acute pancreatitis

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12 December 2020

The catalytic site residues and interfacial binding of human pancreatic lipase

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12 December 2020

Disulfide-linked propeptides stabilize the structure of zymogen and mature pancreatic serine proteases

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12 December 2020

Limited proteolyses in pancreatic chymotrypsinogens and trypsinogens

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12 December 2020

Bile salt-stimulated carboxyl ester lipase influences lipoprotein assembly and secretion in intestine: a process mediated via ceramide hydrolysis

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12 December 2020

Hydrolysis of retinyl esters by pancreatic triglyceride lipase

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12 December 2020

Value of genetic testing in the management of pancreatitis

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12 December 2020

The cystic fibrosis transmembrane conductance regulator gene and ion channel function in patients with idiopathic pancreatitis

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12 December 2020

Salivary isoamylase in duodenal aspirates

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12 December 2020

Structure of human salivary alpha-amylase at 1.6 A resolution: implications for its role in the oral cavity

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12 December 2020

Discoordinate expression of pancreatic lipase and two related proteins in the human fetal pancreas

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12 December 2020

On zymogens of human pancreatic juice

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12 December 2020

Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens

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12 December 2020

Human pancreatic chymotrypsinogen A: a non-competitive enzyme immunoassay, and molecular forms in serum and amniotic fluid

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12 December 2020

Subcellular kinetics of early trypsinogen activation in acute rodent pancreatitis

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12 December 2020

Three dimensional structure of porcine pancreatic alpha-amylase at 2.9 A resolution. Role of calcium in structure and activity

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12 December 2020

Selective pancreatic deficiency, absent amylase, diminished trypsin, and normal lipase

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12 December 2020

Hydrolysis of human milk fat globules by pancreatic lipase: role of colipase, phospholipase A2, and bile salts

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12 December 2020

Comparative biochemical studies of milks. IV. Constituent fatty acids of milk fats

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12 December 2020

Corrected sequences of cDNAs for human salivary and pancreatic alpha-amylases [corrected]

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12 December 2020

Development of functional responses in human exocrine pancreas

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12 December 2020

Digestion and absorption of tube-feeding emulsions with different droplet sizes and compositions in the rat

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12 December 2020

Quantitative study of digestive enzyme secretion and gastrointestinal lipolysis in chronic pancreatitis

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12 December 2020

Possible lysosomal activation of pancreatic zymogens. Activation of both human trypsinogens by cathepsin B and spontaneous acid. Activation of human trypsinogen 1

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12 December 2020

Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA

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12 December 2020

Characterization of human exocrine pancreatic proteins by two-dimensional isoelectric focusing/sodium dodecyl sulfate gel electrophoresis.

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12 December 2020

Effects of decreasing intraluminal amylase activity on starch digestion and postprandial gastrointestinal function in humans.

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12 December 2020

Decreased neonatal dietary fat absorption and T cell cytotoxicity in pancreatic lipase-related protein 2-deficient mice

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12 December 2020

Porcine pancreatic alpha-amylase hydrolysis of hydroxyethylated amylose and specificity of subsite binding

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12 December 2020

Starch digestion in normal subjects and patients with pancreatic disease, using a 13CO2 breath test

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12 December 2020

Gastric emptying and lingual lipase activity in cystic fibrosis

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12 December 2020

Digestive lipases of the newborn ferret: compensatory role of milk bile salt-dependent lipase

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12 December 2020

Complex carbohydrate malabsorption in exocrine pancreatic insufficiency

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12 December 2020

A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis

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12 December 2020

Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis

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12 December 2020

Trypsinogen variants in pancreatic juice of healthy volunteers, chronic alcoholics, and patients with pancreatitis and cancer of the pancreas

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12 December 2020

The Action Pattern of Porcine Pancreatic α-Amylase in Relationship to the Substrate Binding Site of the Enzyme

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12 December 2020

Relations between Pancreatic Enzyme Outputs and Malabsorption in Severe Pancreatic Insufficiency

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12 December 2020

Assimilation of wheat starch in patients with chronic pancreatitis. Positive effect of enzyme replacement

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12 December 2020

Fate of pancreatic enzymes during small intestinal aboral transit in humans

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12 December 2020

Clinical relevance of proteinase activated receptors (pars) in the gut

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12 December 2020

Structure and activity of rat pancreatic lipase-related protein 2

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12 December 2020

The lipase C-terminal domain. A novel unusual inhibitor of pancreatic lipase activity

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12 December 2020

Triglyceride structure of human milk fat

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12 December 2020

Studies on fat digestion, absorption, and transport in the suckling rat. II. Triacylglycerols: molecular species, stereospecific analysis, and specificity of hydrolysis by lingual lipase

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12 December 2020

Lipase isoforms and amylase isoenzymes: assays and application in the diagnosis of acute pancreatitis.

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12 December 2020

The clinical significance of salivary amylase in duodenal aspirates in evaluation of exocrine pancreas function

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12 December 2020

The specific activities of human digestive lipases measured from the in vivo and in vitro lipolysis of test meals

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12 December 2020

INTRAMOLECULAR FATTY ACID DISTRIBUTION IN THE MILK FAT TRIGLYCERIDES OF SEVERAL SPECIES

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12 December 2020

Chromatography of trypsin and its derivatives. Characterization of a new active form of bovine trypsin

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12 December 2020

Analysis of human exocrine pancreatic proteins by means of pore gradient polyacrylamide gel electrophoresis.

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12 December 2020

Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation.

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12 December 2020

The role of gastric lipolysis on fat absorption and bile acid metabolism in the rat

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12 December 2020

The Comparative Biochemistry, Physiology, and Genetics of Animal α-Amylases

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12 December 2020

Evolutionary silencing of the human elastase I gene (ELA1)

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12 December 2020

Pancreatic triglyceride lipase deficiency minimally affects dietary fat absorption but dramatically decreases dietary cholesterol absorption in mice

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12 December 2020

Intestinal Absorption of Dietary Cholesteryl Ester Is Decreased but Retinyl Ester Absorption Is Normal in Carboxyl Ester Lipase Knockout Mice†

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12 December 2020

Characterization of emulsions and lipolysis of dietary lipids in the human stomach.

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12 December 2020

An autolyzed and still active form of bovine trypsin

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12 December 2020

Effects of dietary consistency and water content on parotid amylase secretion and gastric starch digestion in rats

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12 December 2020

A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis

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12 December 2020

Structure of human pancreatic lipase

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12 December 2020

Cloning and characterization of human pancreatic lipase cDNA.

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12 December 2020

Cloning and characterization of the human colipase cDNA

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12 December 2020

Mechanisms of Inhibition of Triacylglycerol Hydrolysis by Human Gastric Lipase

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12 December 2020

Stereospecificity of lipases. Enzymatic hydrolysis of enantiomeric alkyldiacyl- and dialkylacylglycerols by lipoprotein lipase

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12 December 2020

Novel cationic trypsinogen (PRSS1) N29T and R122C mutations cause autosomal dominant hereditary pancreatitis

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12 December 2020

Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity

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12 December 2020

The Digestive Enzymes of the Pancreas: A Mixture of Inconstant Proportions

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12 December 2020

Human pancreatic lipase-related protein 2 is a galactolipase

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12 December 2020

Fecal elastase 1 determination in chronic pancreatitis

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12 December 2020

Elevated calcium and activation of trypsinogen in rat pancreatic acini

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12 December 2020

cDNA cloning of human-milk bile-salt-stimulated lipase and evidence for its identity to pancreatic carboxylic ester hydrolase

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12 December 2020

The structure of truncated recombinant human bile salt-stimulated lipase reveals bile salt-independent conformational flexibility at the active-site loop and provides insights into heparin binding

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12 December 2020

Structure and activity of human pancreasin, a novel tryptic serine peptidase expressed primarily by the pancreas

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12 December 2020

Importance of phospholipids, pancreatic phospholipase A2, and fatty acid for the digestion of dietary fat: in vitro experiments with the porcine enzymes

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12 December 2020

Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis

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12 December 2020

Modeling studies of the change in conformation required for cleavage of limited proteolytic sites

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12 December 2020

The effect of substrate modification on porcine pancreatic alpha-amylase subsite binding: hydrolysis of substrates containing 2-deoxy-D-glucose and 2-amino-2-deoxy-D-glucose

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12 December 2020

The effect of substrate modification on binding of porcine pancreatic alpha amylase: hydrolysis of modified amylose containing D-allose residues

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12 December 2020

Elastin: relation of protein and gene structure to disease

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12 December 2020

Enterokinase, the initiator of intestinal digestion, is a mosaic protease composed of a distinctive assortment of domains

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12 December 2020

Human milk lipases. I. Serum-stimulated lipase

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12 December 2020

Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

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12 December 2020

Pancreatic lipase-related protein 2 is the major colipase-dependent pancreatic lipase in suckling mice

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12 December 2020

Fecal pancreatic elastase 1 is inaccurate in the diagnosis of chronic pancreatitis.

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12 December 2020

Physical and chemical transformations of cereal food during oral digestion in human subjects

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12 December 2020

Clinical practice. Acute pancreatitis

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12 December 2020

The binding of Ca2 to trypsinogen and its relation to the mechanism of activation

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12 December 2020

ERCP findings in idiopathic pancreatitis: patients who are cystic fibrosis gene positive and negative.

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12 December 2020

Protease-activated receptors: contribution to physiology and disease

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12 December 2020

Comparative studies on the mechanism of activation of the two human trypsinogens

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12 December 2020

CHANGES IN THE PATTERN OF CARBOHYDRATE CONSUMPTION IN BRITAIN

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12 December 2020

Hydrolysis of milk fat globules by pancreatic lipase. Role of colipase, phospholipase A2, and bile salts

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12 December 2020

Early trypsinogen activation in acute pancreatitis

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12 December 2020

Digestion and absorption of 2 fat emulsions with different droplet sizes in the human digestive tract

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12 December 2020

Does the bile salt-stimulated lipase of human milk have a role in the use of the milk long-chain polyunsaturated fatty acids?

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12 December 2020

Mechanisms of zymogen activation

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12 December 2020

The alpha/beta hydrolase fold

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12 December 2020

Isolated co-lipase deficiency in two brothers

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12 December 2020

The contribution of salivary amylase to glucose polymer hydrolysis in premature infants

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12 December 2020

Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-ray crystallography

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12 December 2020

Physiology and pathophysiology of intestinal absorption

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12 December 2020

The complete 685-kilobase DNA sequence of the human beta T cell receptor locus

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12 December 2020

Crystallization of pancreatic procolipase and of its complex with pancreatic lipase

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12 December 2020

Effect of human milk or formula on gastric function and fat digestion in the premature infant.

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12 December 2020

The commercially available ELISA for pancreatic elastase 1 based on polyclonal antibodies does measure an as yet unknown antigen different from purified elastase 1. Binding studies and clinical use in patients with exocrine pancreatic insufficiency

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12 December 2020

Digestion of triacylglycerols containing long-chain polyenoic fatty acids in vitro by colipase-dependent pancreatic lipase and human milk bile salt-stimulated lipase.

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12 December 2020

Polymorphisms in PNLIP, encoding pancreatic lipase, and associations with metabolic traits

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12 December 2020

Rat pancreatic lipase and two related proteins: enzymatic properties and mRNA expression during development

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12 December 2020

Genetic predispositions to acute and chronic pancreatitis

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12 December 2020

The triglyceride lipases of the pancreas

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12 December 2020

Multiple attack and polarity of action of porcine pancreatic α-amylase

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12 December 2020

A zymogen of phospholipase A in human pancreatic juice

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12 December 2020

Secretion and contribution to lipolysis of gastric and pancreatic lipases during a test meal in humans

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12 December 2020

Role of nonpancreatic lipolytic activity in exocrine pancreatic insufficiency.

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12 December 2020

Compensatory phospholipid digestion is required for cholesterol absorption in pancreatic phospholipase A(2)-deficient mice

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12 December 2020

Congenital pancreatic lipase deficiency

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12 December 2020

Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

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12 December 2020

Human preduodenal lipase is entirely of gastric fundic origin

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12 December 2020

Reactivation of the totally inactive pancreatic lipase RP1 by structure-predicted point mutations

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12 December 2020

Trypsin IV, a novel agonist of protease-activated receptors 2 and 4.

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12 December 2020

Fecal elastase test: evaluation of a new noninvasive pancreatic function test

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12 December 2020

Hydrolysis of triacylglycerol arachidonic and linoleic acid ester bonds by human pancreatic lipase and carboxyl ester lipase

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12 December 2020

Physicochemical characteristics of emulsions during fat digestion in human stomach and duodenum.

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12 December 2020

Decreased postnatal survival and altered body weight regulation in procolipase-deficient mice

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12 December 2020

Comprehensive Proteomic Analysis of Human Pancreatic Juice

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12 December 2020

A novel human chymotrypsin-like digestive enzyme

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12 December 2020

One-step purification of procolipase from human pancreatic juice by immobilized antibodies against human colipase86

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12 December 2020

The complete digestion of human milk triacylglycerol in vitro requires gastric lipase, pancreatic colipase-dependent lipase, and bile salt-stimulated lipase

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12 December 2020

Purification of pancreatic phospholipase A2 from human duodenal juice

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12 December 2020

Inhibitory effect of the pancreatic lipase C-terminal domain on intestinal lipolysis in rats fed a high-fat diet: chronic study

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12 December 2020

Fecal elastase-1 is superior to fecal chymotrypsin in the assessment of pancreatic involvement in cystic fibrosis.

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12 December 2020

Characterization of pancreatic elastase II cDNAs: two elastase II mRNAs are expressed in human pancreas

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12 December 2020

Pancreatic lipase-related protein type I: a specialized lipase or an inactive enzyme.

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12 December 2020

Human pancreatic triglyceride lipase expressed in yeast cells: purification and characterization

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12 December 2020

Signal transduction, calcium and acute pancreatitis.

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12 December 2020

Lipolysis of menhaden oil triacylglycerols and the corresponding fatty acid alkyl esters by pancreatic lipase in vitro: a reexamination.

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12 December 2020

I. Serine proteinases. The structure of alpha-chymotrypsin

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12 December 2020

Faecal bile acid and dietary residue excretion in cystic fibrosis: age group variations.

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12 December 2020

Mesotrypsin: a new inhibitor-resistant protease from a zymogen in human pancreatic tissue and fluid

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12 December 2020

Effect of heat treatment of human milk on absorption of nitrogen, fat, sodium, calcium, and phosphorus by preterm infants

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12 December 2020

Crystal structure of human gastric lipase and model of lysosomal acid lipase, two lipolytic enzymes of medical interest

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12 December 2020

Selective deficiency of pancreatic amylase

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12 December 2020

Inhibition of cathepsin B does not affect the intracellular activation of trypsinogen by cerulein hyperstimulation in isolated rat pancreatic acinar cells

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12 December 2020

Two mutations in rat trypsin confer resistance against autolysis.

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12 December 2020

Molecular cloning and expression of human caldecrin

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12 December 2020

Hydrolysis of galactolipids by human pancreatic lipolytic enzymes and duodenal contents.

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12 December 2020

Structural and Functional Aspects of Domain Motions in Proteins

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12 December 2020

Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases

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12 December 2020

Lingual lipase in cystic fibrosis. Quantitation of enzyme activity in the upper small intestine of patients with exocrine pancreatic insufficiency

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12 December 2020

10.1007/S10620-006-9589-Z

Identifiers

DOI

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15 August 2017

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PubMed ID

17205399