Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation. (Q36702768)

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22 February 2020

title

Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation (English)

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22 February 2020

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2

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22 February 2020

Robert Guzy

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22 February 2020

author name string

Gregory B Waypa

1

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22 February 2020

Paul T Mungai

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22 February 2020

Jacqueline M Schriewer

5

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22 February 2020

Danijela Dokic

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22 February 2020

Molly K Ball

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22 February 2020

Paul T Schumacker

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22 February 2020

language of work or name

English

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publication date

17 January 2013

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American Journal of Respiratory and Critical Care Medicine

22 February 2020

published in

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22 February 2020

volume

187

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22 February 2020

issue

4

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22 February 2020

page(s)

424-432

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Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels

22 February 2020

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Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells

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Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCepsilon signaling axis in pulmonary artery smooth muscle cells.

30 September 2017

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Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis.

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Role of mitochondrial reactive oxygen species in hypoxia-dependent increase in intracellular calcium in pulmonary artery myocytes

30 September 2017

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Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange

30 September 2017

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30 September 2017

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A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system

30 September 2017

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Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

30 September 2017

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Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

30 September 2017

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Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators

30 September 2017

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Hypoxic pulmonary vasoconstriction: cyclic adenosine diphosphate-ribose, smooth muscle Ca(2+) stores and the endothelium

30 September 2017

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Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor

30 September 2017

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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

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30 September 2017

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5 September 2018

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5 September 2018

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5 September 2018

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5 September 2018

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5 September 2018

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5 September 2018

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Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells

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22 February 2020

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