"Spicing up" of the immune system by curcumin (Q36702820)

15 August 2017

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title

"Spicing up" of the immune system by curcumin (English)

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15 August 2017

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Ganesh Chandra Jagetia

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1

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PubMed ID

17211725

15 August 2017

Bharat B Aggarwal

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2

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15 August 2017

9 January 2007

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Journal of Clinical Immunology

15 August 2017

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15 August 2017

27

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15 August 2017

19-35

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15 August 2017

1

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https://scigraph.springernature.com/pub.10.1007/s10875-006-9066-7

15 August 2017

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cites work

Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent.

1 reference

https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Curcumin inhibits activation of Vgamma9Vdelta2 T cells by phosphoantigens and induces apoptosis involving apoptosis-inducing factor and large scale DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kappa B as potential targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Effects of curcumin on tumour necrosis factor-alpha and interleukin-6 in the late phase of experimental acute pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Unexpected transcriptional induction of monocyte chemoattractant protein 1 by proteasome inhibition: involvement of the c-Jun N-terminal kinase-activator protein 1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Curcumin-attenuated trinitrobenzene sulphonic acid induces chronic colitis by inhibiting expression of cyclooxygenase-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Preventive and therapeutic effects of NF-kappaB inhibitor curcumin in rats colitis induced by trinitrobenzene sulfonic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Curcumin attenuates DNB-induced murine colitis.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10875-006-9066-7

Curcumin attenuates allergen-induced airway hyperresponsiveness in sensitized guinea pigs

21 January 2018

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12 December 2020

Effect of curcumin on immune function of mice

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12 December 2020

Plant products as topical microbicide candidates: assessment of in vitro and in vivo activity against herpes simplex virus type 2.

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12 December 2020

Curcumin ameliorates left ventricular function in rabbits with pressure overload: inhibition of the remodeling of the left ventricular collagen network associated with suppression of myocardial tumor necrosis factor-alpha and matrix metalloproteinas

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12 December 2020

Curcuminoids inhibit the angiogenic response stimulated by fibroblast growth factor-2, including expression of matrix metalloproteinase gelatinase B

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12 December 2020

Effects of the phytochemicals, curcumin and quercetin, upon azoxymethane-induced colon cancer and 7,12-dimethylbenz[a]anthracene-induced mammary cancer in rats.

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12 December 2020

Curcuma longa inhibits TNF-alpha induced expression of adhesion molecules on human umbilical vein endothelial cells

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12 December 2020

Drug-induced suppression of phosphorylase kinase activity correlates with resolution of psoriasis as assessed by clinical, histological and immunohistochemical parameters

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12 December 2020

Differential regulation of cytokines and transcription factors in liver by curcumin following hemorrhage/resuscitation

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12 December 2020

Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells

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12 December 2020

Inhibition of intestinal tumors by curcumin is associated with changes in the intestinal immune cell profile

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12 December 2020

Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis

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12 December 2020

Curcumin causes the growth arrest and apoptosis of B cell lymphoma by downregulation of egr-1, c-myc, bcl-XL, NF-kappa B, and p53.

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12 December 2020

Effect of tumor necrosis factor-alpha and interleukin-1 alpha on heme oxygenase-1 expression in human endothelial cells

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12 December 2020

Curcumin-induced inhibition of cellular reactive oxygen species generation: novel therapeutic implications

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12 December 2020

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12 December 2020

Inhibition of the HIV-1 and HIV-2 proteases by curcumin and curcumin boron complexes

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12 December 2020

Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication

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12 December 2020

Anti-inflammatory and irritant activities of curcumin analogues in rats

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12 December 2020

Inhibition of nuclear factor kappaB by direct modification in whole cells--mechanism of action of nordihydroguaiaritic acid, curcumin and thiol modifiers.

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12 December 2020

Effect of natural food colorings on immunoglobulin production in vitro by rat spleen lymphocytes

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12 December 2020

Inhibition of human immunodeficiency virus type-1 integrase by curcumin

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12 December 2020

Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice

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12 December 2020

Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-kappaB activation

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12 December 2020

Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells

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12 December 2020

Effects of nuclear factor-kappaB inhibitors and its implication on natural killer T-cell lymphoma cells

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12 December 2020

Antifungal activity of turmeric oil extracted from Curcuma longa (Zingiberaceae).

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12 December 2020

The effect of turmeric extracts on inflammatory mediator production

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12 December 2020

Dose escalation of a curcuminoid formulation

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12 December 2020

Chemoprevention of mammary tumor virus-induced and chemical carcinogen-induced rodent mammary tumors by natural plant products

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12 December 2020

Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells

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12 December 2020

Clinical development of leukocyte cyclooxygenase 2 activity as a systemic biomarker for cancer chemopreventive agents.

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12 December 2020

Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated prot

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12 December 2020

The sensitive fluorimetric method for the determination of curcumin using the enhancement of mixed micelle

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12 December 2020

Immunomodulatory activity of curcumin: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production in vitro

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12 December 2020

Is the effect of interleukin-1 on glutathione oxidation in cultured human fibroblasts involved in nuclear factor-kappaB activation?

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12 December 2020

Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5).

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12 December 2020

Effect of curcumin on the apoptosis of rodent and human nonproliferating and proliferating lymphoid cells.

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12 December 2020

Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophages by curcumin

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12 December 2020

Regulation of interleukin-8 gene expression by interleukin-1beta, osteotropic hormones, and protein kinase inhibitors in normal human bone marrow stromal cells

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12 December 2020

Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages

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12 December 2020

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

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12 December 2020

Curcumin enhances wound healing in streptozotocin induced diabetic rats and genetically diabetic mice

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12 December 2020

Curcumin inhibits mitogen stimulated lymphocyte proliferation, NFkappaB activation, and IL-2 signaling

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12 December 2020

The anti-inflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-gamma

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12 December 2020

The antioxidants curcumin and quercetin inhibit inflammatory processes associated with arthritis

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12 December 2020

Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions

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12 December 2020

Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation

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12 December 2020

Quercetin and curcumin up-regulate antioxidant gene expression in rat kidney after ureteral obstruction or ischemia/reperfusion injury

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12 December 2020

Blocking NF-kappaB activation may be an effective strategy in the fever therapy

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12 December 2020

Stability of curcumin in buffer solutions and characterization of its degradation products.

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12 December 2020

Inhibition of 5-hydroxy-eicosatetraenoic acid (5-HETE) formation in intact human neutrophils by naturally-occurring diarylheptanoids: inhibitory activities of curcuminoids and yakuchinones

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12 December 2020

Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines

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12 December 2020

Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound

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12 December 2020

Differential modulation of nitric oxide production by curcumin in host macrophages and NK cells

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12 December 2020

CD14-mediated signal pathway of Porphyromonas gingivalis lipopolysaccharide in human gingival fibroblasts

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12 December 2020

Curcumin and curcumin derivatives inhibit Tat-mediated transactivation of type 1 human immunodeficiency virus long terminal repeat

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12 December 2020

Anti-tumour and antioxidant activity of natural curcuminoids

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12 December 2020

Curcumin differentially modulates mRNA profiles in Jurkat T and human peripheral blood mononuclear cells

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12 December 2020

Curcumin inhibits interferon-alpha induced NF-kappaB and COX-2 in human A549 non-small cell lung cancer cells

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12 December 2020

Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kappaB transcriptional activity in MCF10A human breast epithelial cells.

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12 December 2020

Testing of lipoxygenase inhibitors, cyclooxygenase inhibitors, drugs with immunomodulating properties and some reference antipsoriatic drugs in the modified mouse tail test, an animal model of psoriasis

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12 December 2020

Immunomodulatory activity of curcumin

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12 December 2020

Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation

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12 December 2020

Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis

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12 December 2020

Protective role of curcumin against isoproterenol induced myocardial infarction in rats

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12 December 2020

Cytotoxicity, antioxidant and anti-inflammatory activities of curcumins I-III from Curcuma longa

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12 December 2020

Curcumin: a new radio-sensitizer of squamous cell carcinoma cells.

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12 December 2020

Anti-inflammatory studies on Curcuma longa (turmeric)

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12 December 2020

Hypoglycemic effects of turmeric (Curcuma longa L. rhizomes) on genetically diabetic KK-Ay mice

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12 December 2020

Cyclooxygenase-2 expression and oxidative DNA adducts in murine intestinal adenomas: modification by dietary curcumin and implications for clinical trials

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12 December 2020

Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages

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12 December 2020

The effect of curcumin on human B-cell immortalization by Epstein-Barr virus.

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12 December 2020

Induction of G2/M arrest and inhibition of cyclooxygenase-2 activity by curcumin in human bladder cancer T24 cells.

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12 December 2020

Hypolipidemic action of curcumin, the active principle of turmeric (Curcuma longa) in streptozotocin induced diabetic rats

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12 December 2020

Origin, maturation and antigen presenting function of dendritic cells.

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12 December 2020

Dietary n-3 fatty acids, curcumin and capsaicin lower the release of lysosomal enzymes and eicosanoids in rat peritoneal macrophages

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12 December 2020

Prevention of ischaemia-induced biochemical changes by curcumin & quinidine in the cat heart

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12 December 2020

Chemopreventive efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis.

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12 December 2020

Curcumin inhibits Th1 cytokine profile in CD4+ T cells by suppressing interleukin-12 production in macrophages

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12 December 2020

Role of capsaicin, curcumin and dietary n-3 fatty acids in lowering the generation of reactive oxygen species in rat peritoneal macrophages

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12 December 2020

Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor

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12 December 2020

Protective effects of chlorogenic acid, curcumin and beta-carotene against gamma-radiation-induced in vivo chromosomal damage

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12 December 2020

Modification of radiation-induced acute oral mucositis in the rat.

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12 December 2020

Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]

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12 December 2020

Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression, by curcumin and its analog, alpha-diisoeugenol

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12 December 2020

Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma

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12 December 2020

Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1.

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12 December 2020

Relative contribution of NF-kappaB and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbamate of the UVB-induced cytokine expression by keratinocytes

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12 December 2020

Chemosensitization and radiosensitization of tumors by plant polyphenols

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12 December 2020

Enhancement of wound healing by curcumin in animals

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12 December 2020

Inhibition of tumor necrosis factor by curcumin, a phytochemical

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12 December 2020

Curcumin suppresses interleukin 1beta-mediated microsomal prostaglandin E synthase 1 by altering early growth response gene 1 and other signaling pathways

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12 December 2020

Immunomodulatory effects of curcumin

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12 December 2020

Effects of dietary fats and curcumin on IgE-mediated degranulation of intestinal mast cells in brown Norway rats

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12 December 2020

Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: suppression of p38, JNK and NF-kappaB p65 as potential targets

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12 December 2020

Effect of curcumin and eugenol on iron-induced hepatic toxicity in rats

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12 December 2020

Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase

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12 December 2020

Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate

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12 December 2020

Elucidation of anti-allergic activities of curcumin-related compounds with a special reference to their anti-oxidative activities

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12 December 2020

Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction

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12 December 2020

Curcumin suppresses growth of head and neck squamous cell carcinoma

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12 December 2020

The dendritic cell system and its role in immunogenicity

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12 December 2020

Protective effect of curcumin on myocardial ischemia reperfusion injury in rats

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12 December 2020

Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription

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12 December 2020

Pharmacology of Curcuma longa

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12 December 2020

Curcumin (diferuloylmethane) inhibits constitutive active NF-kappaB, leading to suppression of cell growth of human T-cell leukemia virus type I-infected T-cell lines and primary adult T-cell leukemia cells

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12 December 2020

Curcumin inhibits IL1 alpha and TNF-alpha induction of AP-1 and NF-kB DNA-binding activity in bone marrow stromal cells

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12 December 2020

Curcumin suppresses constitutive activation of AP-1 by downregulation of JunD protein in HTLV-1-infected T-cell lines

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12 December 2020

A curcuminoid and sesquiterpenes as inhibitors of macrophage TNF-alpha release from Curcuma zedoaria

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12 December 2020

Roles of intracellular calcium and NF-kappaB in the Bacillus Calmette-Guérin-induced secretion of interleukin-8 from human monocytes

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12 December 2020

Antioxidant effect of tetrahydrocurcumin in streptozotocin-nicotinamide induced diabetic rats

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12 December 2020

Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4.

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12 December 2020

Antibacterial activity of turmeric oil: a byproduct from curcumin manufacture

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12 December 2020

Dendritic cells and the control of immunity

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12 December 2020

Anticancer potential of curcumin: preclinical and clinical studies.

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12 December 2020

Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex

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12 December 2020

Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3.

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12 December 2020

Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity

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12 December 2020

Inhibition of neutrophil response by curcumin

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12 December 2020

Curcumin blocks HIV protease inhibitor ritonavir-induced vascular dysfunction in porcine coronary arteries

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12 December 2020

Active site binding modes of curcumin in HIV-1 protease and integrase

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12 December 2020

Curcumin blocks cyclosporine A-resistant CD28 costimulatory pathway of human T-cell proliferation

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12 December 2020

Curcumin inhibits neurotensin-mediated interleukin-8 production and migration of HCT116 human colon cancer cells

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12 December 2020

Protection of pancreatic beta-cell by the potential antioxidant bis-o-hydroxycinnamoyl methane, analogue of natural curcuminoid in experimental diabetes.

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12 December 2020

Effects of three dietary phytochemicals from tea, rosemary and turmeric on inflammation-induced nitrite production

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12 December 2020

Curcumin inhibition of Dermatophagoides farinea-induced interleukin-5 (IL-5) and granulocyte macrophage-colony stimulating factor (GM-CSF) production by lymphocytes from bronchial asthmatics

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12 December 2020

Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats

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12 December 2020

Influence of dietary curcumin and cholesterol on the progression of experimentally induced diabetes in albino rat.

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12 December 2020

Inhibition of proliferation and apoptosis of human and rat T lymphocytes by curcumin, a curry pigment

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12 December 2020

Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer's disease patients

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12 December 2020

Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis and DMBA-DNA adduct formation by curcumin

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12 December 2020

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

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12 December 2020

Curcumin-induced apoptosis in scleroderma lung fibroblasts: role of protein kinase cepsilon.

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12 December 2020

Dietary curcumin enhances antibody response in rats

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12 December 2020

Inhibition of homodimerization of Toll-like receptor 4 by curcumin

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12 December 2020

Curcumin therapy in inflammatory bowel disease: a pilot study

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12 December 2020

Curcumin, a compound with anti-inflammatory and anti-oxidant properties, down-regulates chemokine expression in bone marrow stromal cells.

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12 December 2020

In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties.

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12 December 2020

Inhibitory effects of curcumin on tumor initiation by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene

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12 December 2020

Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions.

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12 December 2020

Effect of bioflavonoids quercetin and curcumin on ischemic renal injury: a new class of renoprotective agents

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12 December 2020

Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the cell surface:impact on human pancreatic carcinoma cell growth by autocrine regulation

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12 December 2020

Dendritic cells are the principal cells in mouse spleen bearing immunogenic fragments of foreign proteins

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12 December 2020

10.1007/S10875-006-9066-7

Identifiers

DOI

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15 August 2017

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PubMed ID

17211725