Beta-adrenoceptor blocker treatment and the cardiac beta-adrenoceptor-G-protein(s)-adenylyl cyclase system in chronic heart failure (Q36704776)

15 August 2017

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title

Beta-adrenoceptor blocker treatment and the cardiac beta-adrenoceptor-G-protein(s)-adenylyl cyclase system in chronic heart failure (English)

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15 August 2017

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chronic heart failure

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Otto-Erich Brodde

1

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15 August 2017

11 January 2007

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Naunyn-Schmiedeberg's Archives of Pharmacology

15 August 2017

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15 August 2017

374

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15 August 2017

5-6

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15 August 2017

361-372

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https://scigraph.springernature.com/pub.10.1007/s00210-006-0125-7

15 August 2017

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Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by beta-adrenergic receptor stimulation and blockade

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Beta-adrenoceptor polymorphisms

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Selective regulation of beta 1- and beta 2-adrenoceptors in the human heart by chronic beta-adrenoceptor antagonist treatment

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Inverse agonism and the regulation of receptor number

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Chronic beta 1-adrenoceptor antagonist treatment sensitizes beta 2-adrenoceptors, but desensitizes M2-muscarinic receptors in the human right atrium

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Cardiac sympathetic nerve function in congestive heart failure

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12 December 2020

Inhibitory G-proteins and their role in desensitization of the adenylyl cyclase pathway in heart failure.

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12 December 2020

Effects of beta-adrenoceptor antagonist administration on beta 2-adrenoceptor density in human lymphocytes. The role of the "intrinsic sympathomimetic activity"

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The Arg389Gly beta1-adrenoceptor polymorphism and catecholamine effects on plasma-renin activity

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Subtype-selective up-regulation of human saphenous vein beta 2-adrenoceptors by chronic beta-adrenoceptor antagonist treatment

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Characterization of beta(1)-selectivity, adrenoceptor-G(s)-protein interaction and inverse agonism of nebivolol in human myocardium

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12 December 2020

The gain-of-function G389R variant of the beta1-adrenoceptor does not influence blood pressure or heart rate response to beta-blockade in hypertensive subjects

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12 December 2020

What is the role of beta-adrenergic signaling in heart failure?

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12 December 2020

G-protein signaling: back to the future

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12 December 2020

Adrenergic nervous system in heart failure

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12 December 2020

Beta-adrenoceptor changes in blood lymphocytes and altered drug responsiveness

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12 December 2020

Genetic manipulation of myocardial beta-adrenergic receptor activation and desensitization

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12 December 2020

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

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12 December 2020

Increased beta-receptor density and improved hemodynamic response to catecholamine stimulation during long-term metoprolol therapy in heart failure from dilated cardiomyopathy

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12 December 2020

Functional responses of human beta1 adrenoceptors with defined haplotypes for the common 389R>G and 49S>G polymorphisms.

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12 December 2020

Reduced beta-adrenergic receptor activation decreases G-protein expression and beta-adrenergic receptor kinase activity in porcine heart

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12 December 2020

Regulation of G protein-coupled receptor kinases

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12 December 2020

Inactivation of (Gialpha) proteins increases arrhythmogenic effects of beta-adrenergic stimulation in the heart

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12 December 2020

Effects of metoprolol on myocardial beta-adrenoceptors and Gi alpha-proteins in patients with congestive heart failure

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12 December 2020

Different intrinsic activities of bucindolol, carvedilol and metoprolol in human failing myocardium

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12 December 2020

An evaluation of the beta-1 adrenergic receptor Arg389Gly polymorphism in individuals with heart failure: a MERIT-HF sub-study

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12 December 2020

Changes in the density of beta adrenergic receptors in rat lymphocytes, heart and lung after chronic treatment with propranolol

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12 December 2020

Subtype-specific beta-adrenoceptor signaling pathways in the heart and their potential clinical implications

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12 December 2020

Autonomic receptor systems in the failing and aging human heart: similarities and differences

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12 December 2020

Bucindolol displays intrinsic sympathomimetic activity in human myocardium

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12 December 2020

Carvedilol but not metoprolol reduces beta-adrenergic responsiveness after complete elimination from plasma in vivo

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12 December 2020

Adrenergic and muscarinic receptors in the human heart

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12 December 2020

Cardiac adrenoceptors: physiological and pathophysiological relevance

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12 December 2020

A novel polymorphism in the gene coding for the beta(1)-adrenergic receptor associated with survival in patients with heart failure

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12 December 2020

Unchanged G-protein-coupled receptor kinase activity in the aging human heart

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12 December 2020

Autonomic nervous system pharmacogenomics: a progress report

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12 December 2020

G-protein-coupled receptor kinase activity in human heart failure: effects of beta-adrenoceptor blockade

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12 December 2020

Effects of two Gbetagamma-binding proteins--N-terminally truncated phosducin and beta-adrenergic receptor kinase C terminus (betaARKct)--in heart failure

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12 December 2020

Altered beta-adrenergic receptor gene regulation and signaling in chronic heart failure

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12 December 2020

Ser49Gly of beta1-adrenergic receptor is associated with effective beta-blocker dose in dilated cardiomyopathy

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12 December 2020

Evidence for reduction of norepinephrine uptake sites in the failing human heart

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12 December 2020

Signal transduction mechanisms controlling cardiac contractility and their alterations in chronic heart failure

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12 December 2020

A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure

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12 December 2020

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12 December 2020

In vivo demonstration of cardiac beta 2-adrenoreceptor sensitization by beta 1-antagonist treatment

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12 December 2020

Sympathetic activity and neurotransmitter depletion in congestive heart failure

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12 December 2020

Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases

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12 December 2020

International Union of Pharmacology nomenclature of adrenoceptors

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12 December 2020

beta1-Adrenergic receptor polymorphisms influence the response to metoprolol monotherapy in patients with essential hypertension.

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12 December 2020

Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease

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12 December 2020

Beta-adrenergic receptor polymorphisms: cardiovascular disease associations and pharmacogenetics

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12 December 2020

Loss of adrenergic control of the force-frequency relation in heart failure secondary to idiopathic or ischemic cardiomyopathy

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12 December 2020

Regulation of noradrenaline release by presynaptic receptor systems

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12 December 2020

Pathophysiological targets for beta-blocker therapy in congestive heart failure

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12 December 2020

A study of the adrenotropic receptors

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12 December 2020

Opposing effects of beta(1)- and beta(2)-adrenergic receptors on cardiac myocyte apoptosis : role of a pertussis toxin-sensitive G protein

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12 December 2020

Beta 1-adrenergic receptor polymorphisms and antihypertensive response to metoprolol

1 reference

12 December 2020

Beta1-adrenergic receptor polymorphisms and left ventricular remodeling changes in response to beta-blocker therapy

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12 December 2020

Abnormalities of peripheral sympathetic nervous system control in congestive heart failure.

1 reference

12 December 2020

A NEW ADRENERGIC BETARECEPTOR ANTAGONIST

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12 December 2020

Beta-adrenoceptors in cardiac disease

1 reference

12 December 2020

Gly389Arg polymorphism of β1-adrenergic receptor is associated with the cardiovascular response to metoprolol

1 reference

12 December 2020

β1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure

1 reference

12 December 2020

Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor

1 reference

12 December 2020

Effects of acute and chronic administration of beta-adrenoceptor ligands on airway function in a murine model of asthma

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12 December 2020

Presynaptic regulation of catecholamine release

1 reference

12 December 2020

A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade

1 reference

12 December 2020

Differentiation of Receptor Systems activated by Sympathomimetic Amines

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12 December 2020

Effect of beta-blockade on mortality among high-risk and low-risk patients after myocardial infarction

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12 December 2020

Selective beta 1-adrenoceptor blockade enhances positive inotropic responses to endogenous catecholamines mediated through beta 2-adrenoceptors in human atrial myocardium

1 reference

12 December 2020

Association between beta-1 and beta-2 adrenergic receptor gene polymorphisms and the response to beta-blockade in patients with stable congestive heart failure

1 reference

12 December 2020

Chronic treatment with carbachol sensitizes the myocardium to cAMP-induced arrhythmia

1 reference

12 December 2020

The Arg389Gly beta1-adrenoceptor gene polymorphism determines contractile response to catecholamines

1 reference

12 December 2020

Beta1-adrenergic receptor gene polymorphisms and response to beta1-adrenergic receptor blockade in patients with essential hypertension

1 reference

12 December 2020

Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure

1 reference

12 December 2020

Subtype-selective modulation of human beta 1- and beta 2-adrenoceptor function by beta-adrenoceptor agonists and antagonists

1 reference

12 December 2020

10.1007/S00210-006-0125-7

Identifiers

DOI

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15 August 2017

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PubMed ID

17216434