Clinical proof-of-concept study with MSDC-0160, a prototype mTOT-modulating insulin sensitizer (Q36705829)

15 August 2017

Clinical proof-of-concept study with MSDC-0160, a prototype mTOT-modulating insulin sensitizer (English)

1 reference

15 August 2017

J R Colca

1

1 reference

15 August 2017

J T VanderLugt

2

1 reference

15 August 2017

W J Adams

3

1 reference

15 August 2017

A Shashlo

4

1 reference

15 August 2017

W G McDonald

5

1 reference

15 August 2017

J Liang

6

1 reference

15 August 2017

R Zhou

7

1 reference

15 August 2017

D G Orloff

8

1 reference

15 August 2017

language of work or name

English

0 references

publication date

18 January 2013

1 reference

Clinical Pharmacology & Therapeutics

15 August 2017

1 reference

15 August 2017

93

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15 August 2017

4

1 reference

15 August 2017

352-359

1 reference

Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

Identification and functional expression of the mitochondrial pyruvate carrier

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

Insulin resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor γ-sparing thiazolidinedione

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

Projecting the future diabetes population size and related costs for the U.S.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

beta-cell failure in diabetes and preservation by clinical treatment

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

Contributions of beta-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose

30 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

30 September 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

Insulin sensitizing pharmacology of thiazolidinediones correlates with mitochondrial gene expression rather than activation of PPAR gamma.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

Comparison of cardiovascular outcomes in elderly patients with diabetes who initiated rosiglitazone vs pioglitazone therapy

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

What has prevented the expansion of insulin sensitisers?

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3604641

Pioglitazone and Rosiglitazone Have Different Effects on Serum Lipoprotein Particle Concentrations and Sizes in Patients With Type 2 Diabetes and Dyslipidemia

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23462886

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The mitochondrial pyruvate carrier: has it been unearthed at last?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23462886

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cell biology. Selective insulin sensitizers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23462886

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CLPT.2013.10

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

23462886

1 reference