Targeting acetylcholinesterase to treat neurodegeneration (Q36709537)

15 August 2017

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title

Targeting acetylcholinesterase to treat neurodegeneration (English)

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15 August 2017

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Josef Scheiber

4

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Ulrike Holzgrabe

object named as

Ulrike Holzgrabe

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author name string

Petra Kapková

2

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15 August 2017

Vildan Alptüzün

3

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15 August 2017

Eva Kugelmann

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15 August 2017

language of work or name

English

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publication date

1 February 2007

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Expert Opinion on Therapeutic Targets

15 August 2017

published in

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15 August 2017

volume

11

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15 August 2017

issue

2

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15 August 2017

page(s)

161-179

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Current pharmacotherapy for Alzheimer's disease

15 August 2017

cites work

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Tacrine attenuates hydrogen peroxide-induced apoptosis by regulating expression of apoptosis-related genes in rat PC12 cells

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Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine

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Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Rational approach to discover multipotent anti-Alzheimer drugs.

21 January 2018

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Novel tacrine-melatonin hybrids as dual-acting drugs for Alzheimer disease, with improved acetylcholinesterase inhibitory and antioxidant properties.

21 January 2018

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Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-beta aggregation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Search for dual function inhibitors for Alzheimer's disease: synthesis and biological activity of acetylcholinesterase inhibitors of pyridinium-type and their Abeta fibril formation inhibition capacity

21 January 2018

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Complexes of Alkylene-Linked Tacrine Dimers withTorpedo californicaAcetylcholinesterase: Binding of Bis(5)-tacrine Produces a Dramatic Rearrangement in the Active-Site Gorge

21 January 2018

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Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure

21 January 2018

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Specific Targeting of Acetylcholinesterase and Butyrylcholinesterase Recognition Sites. Rational Design of Novel, Selective, and Highly Potent Cholinesterase Inhibitors

21 January 2018

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Heterodimeric Tacrine-Based Acetylcholinesterase Inhibitors: Investigating Ligand−Peripheral Site Interactions

21 January 2018

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Potent, easily synthesized huperzine A-tacrine hybrid acetylcholinesterase inhibitors

21 January 2018

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10.1517/14728222.11.2.161

21 January 2018

Identifiers

DOI

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15 August 2017

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