A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells (Q36713520)

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scientific article published on 15 April 2008

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English	A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells	scientific article published on 15 April 2008

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells (English)

1 reference

Europe PubMed Central

15 August 2017

author name string

Rebecca H Cho

1

1 reference

Europe PubMed Central

15 August 2017

Hans B Sieburg

2

1 reference

Europe PubMed Central

15 August 2017

Christa E Muller-Sieburg

3

1 reference

Europe PubMed Central

15 August 2017

language of work or name

0 references

publication date

15 April 2008

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

111

1 reference

Europe PubMed Central

15 August 2017

5553-5561

1 reference

Europe PubMed Central

15 August 2017

12

1 reference

Europe PubMed Central

15 August 2017

Long-term propagation of distinct hematopoietic differentiation programs in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

DNA repair is limiting for haematopoietic stem cells during ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

The quantitative trait gene latexin influences the size of the hematopoietic stem cell population in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Clonal diversity of the stem cell compartment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Hematopoietic stem cells do not engraft with absolute efficiencies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Linking age-related defects in B lymphopoiesis to the aging of hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Cell intrinsic alterations underlie hematopoietic stem cell aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Regulation of hematopoietic stem cell aging in vivo by a distinct genetic element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Different in vivo repopulating activities of purified hematopoietic stem cells before and after being stimulated to divide in vitro with the same kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Major age-related changes of mouse hematopoietic stem/progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

The aging of lympho-hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Genetic dissection of age-related changes of immune function in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

T cell senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

High frequency of long-term culture-initiating cells retain in vivo repopulation and self-renewal capacity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Genetic regulation of primitive hematopoietic stem cell senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Evidence for a continuous decline in haemopoietic cell function from birth: application to evaluating bone marrow failure in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

An X chromosome gene regulates hematopoietic stem cell kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Intrinsic and extrinsic control of hemopoietic stem cell numbers: mapping of a stem cell gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Genetic control of the frequency of hematopoietic stem cells in mice: mapping of a candidate locus to chromosome 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Primitive hemopoietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Normal Production of Erythrocytes by Mouse Marrow Continuous for 73 Months

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Two rare populations of mouse Thy-1lo bone marrow cells repopulate the thymus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

30 September 2017

SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

28 June 2018

Age-associated characteristics of murine hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

28 June 2018

Independent homeostatic regulation of B cell compartments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

28 June 2018

Early steps in T cell development are affected by aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

28 June 2018

Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

28 June 2018

The aging of hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

28 June 2018

Lymphoid and erythroid repopulation in B6 W-anemic mice: a new unirradiated recipient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

28 June 2018

Clonal and systemic analysis of long-term hematopoiesis in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

28 June 2018

Impaired thymic regeneration in lethally irradiated mice given bone marrow from aged donors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

28 June 2018

Quantitative genetic variation in the hematopoietic stem cell and progenitor cell compartment and in lifespan are closely linked at multiple loci in BXD recombinant inbred mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

5 September 2018

The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

5 September 2018

Deterministic regulation of hematopoietic stem cell self-renewal and differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

5 September 2018

Age-related change in thymic T-cell development is associated with genetic loci on mouse chromosomes 1, 3, and 11.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

5 September 2018

Age- and stage-specific regulation patterns in the hematopoietic stem cell hierarchy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

5 September 2018

Il-7 and not stem cell factor reverses both the increase in apoptosis and the decline in thymopoiesis seen in aged mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

5 September 2018

Distinct developmental patterns of short-term and long-term functioning lymphoid and myeloid precursors defined by competitive limiting dilution analysis in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

5 September 2018

Maintenance of high levels of pluripotent hematopoietic stem cells in vitro: effect of stromal cells and c-kit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

5 September 2018

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424153

4 December 2018

Development of B cells in aged mice: decline in the ability of pro-B cells to respond to IL-7 but not to other growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cycle initiation and colony formation in culture by murine marrow cells with long-term reconstituting potential in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase activity in candidate stem cells from fetal liver and adult bone marrow

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible expression of CD34 by murine hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired hematopoietic stem cell functioning after serial transplantation and during normal aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maximum life spans in mice are extended by wild strain alleles

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B cell precursors in senescent mice exhibit decreased recruitment into proliferative compartments and altered expression of Bcl-2 family members

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone marrow cells give rise to distinct cell clones within the thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of 5-fluorouracil on "primitive" hematopoietic stem cells that reconstitute whole erythropoiesis of genetically anemic W/Wv mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of bone marrow thymic progenitors in young and aged mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hematopoiesis in the aged: a model of hematopoietic dysregulation?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18413859

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2007-11-123547

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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