Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics (Q36721503)

15 August 2017

Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics (English)

1 reference

15 August 2017

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26

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15 August 2017

Martin Rowe

39

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Elaine Jaffe

Elaine S Jaffe

25

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Elías Campo

Elias Campo

24

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Daniel J. Hodson

Daniel J Hodson

9

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Erlend B. Smeland

27

Erlend B Smeland

1 reference

15 August 2017

40

Sam M Mbulaiteye

1 reference

15 August 2017

Hans Konrad Müller-Hermelink

19

Hans Konrad Müller-Hermelink

1 reference

15 August 2017

21

Randy D Gascoyne

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15 August 2017

35

Wing C Chan

1 reference

15 August 2017

Dennis D Weisenburger

34

Dennis D Weisenburger

1 reference

15 August 2017

22

Joseph M Connors

1 reference

15 August 2017

17

Andreas Rosenwald

1 reference

15 August 2017

36

Stefania Pittaluga

1 reference

15 August 2017

37

Wyndham Wilson

1 reference

15 August 2017

38

Thomas A Waldmann

1 reference

15 August 2017

16

Holger Kohlhammer

1 reference

15 August 2017

8

Arthur L Shaffer

1 reference

15 August 2017

23

Lisa M Rimsza

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15 August 2017

31

Rita M Braziel

1 reference

15 August 2017

3

Michele Ceribelli

1 reference

15 August 2017

11

Xuelu Liu

1 reference

15 August 2017

18

Philip Kluin

1 reference

15 August 2017

28

Martin D Ogwang

1 reference

15 August 2017

Alan Bernard Rickinson

41

Alan B Rickinson

1 reference

15 August 2017

4

Sameer Jhavar

1 reference

15 August 2017

Roland Schmitz

1

1 reference

15 August 2017

Ryan M Young

2

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15 August 2017

Wenming Xiao

5

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15 August 2017

Meili Zhang

6

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15 August 2017

George Wright

7

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15 August 2017

Eric Buras

10

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15 August 2017

John Powell

12

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15 August 2017

Yandan Yang

13

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15 August 2017

Weihong Xu

14

1 reference

15 August 2017

Hong Zhao

15

1 reference

15 August 2017

German Ott

20

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15 August 2017

Steven J Reynolds

29

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15 August 2017

Richard I Fisher

30

1 reference

15 August 2017

Raymond R Tubbs

32

1 reference

15 August 2017

James R Cook

33

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15 August 2017

Louis M Staudt

42

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15 August 2017

language of work or name

English

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publication date

12 August 2012

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15 August 2017

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490

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7418

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15 August 2017

116-120

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https://scigraph.springernature.com/pub.10.1038/nature11378

15 August 2017

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cites work

Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Genome wide copy number analysis of paediatric Burkitt lymphoma using formalin-fixed tissues reveals a subset with gain of chromosome 13q and corresponding miRNA over expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Targeting MYC dependence in cancer by inhibiting BET bromodomains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Analysis of the coding genome of diffuse large B-cell lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Gene expression analysis uncovers similarity and differences among Burkitt lymphoma subtypes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Oncogenically active MYD88 mutations in human lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Cyclin D3 is selectively required for proliferative expansion of germinal center B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Requirement for cyclin D3 in germinal center formation and function.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

miR-19 is a key oncogenic component of mir-17-92

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

E and ID proteins branch out.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Stromal gene signatures in large-B-cell lymphomas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Current investigations and treatment of Burkitt's lymphoma in Africa

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Biology and treatment of Burkitt's lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Lineage dependency and lineage-survival oncogenes in human cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

A loss-of-function RNA interference screen for molecular targets in cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

P38SAPK2 phosphorylates cyclin D3 at Thr-283 and targets it for proteasomal degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

The loop region of the helix-loop-helix protein Id1 is critical for its dominant negative activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Crystal structure of transcription factor E47: E-box recognition by a basic region helix-loop-helix dimer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

PI3 kinase signals BCR-dependent mature B cell survival

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Downregulated expression of SHP-1 in Burkitt lymphomas and germinal center B lymphocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Molecular diagnosis of Burkitt's lymphoma

28 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

5 September 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling.

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609867

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE11378

inferred from DOI database lookup

7 January 2021

based on heuristic

Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE11378

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE11378

1 reference

Dimensions Publication ID

15 August 2017

0 references

1 reference

15 August 2017

1 reference