Targeted inhibition of mammalian target of rapamycin (mTOR) enhances radiosensitivity in pancreatic carcinoma cells (Q36723405)

15 August 2017

Targeted inhibition of mammalian target of rapamycin (mTOR) enhances radiosensitivity in pancreatic carcinoma cells (English)

1 reference

15 August 2017

1 reference

1 reference

Zhi-Jun Dai

1

1 reference

15 August 2017

Jie Gao

2

1 reference

15 August 2017

Hua-Feng Kang

3

1 reference

15 August 2017

Yu-Guang Ma

4

1 reference

15 August 2017

Xiao-Bin Ma

5

1 reference

15 August 2017

Wang-Feng Lu

6

1 reference

15 August 2017

Shuai Lin

7

1 reference

15 August 2017

Hong-Bing Ma

8

1 reference

15 August 2017

Xi-Jing Wang

9

1 reference

15 August 2017

Wen-Ying Wu

10

1 reference

15 August 2017

language of work or name

English

0 references

publication date

19 March 2013

1 reference

Drug Design, Development and Therapy

15 August 2017

1 reference

15 August 2017

7

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15 August 2017

149-159

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Creative Commons Attribution-NonCommercial 3.0 Unported

15 August 2017

start time

1 March 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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mTOR is a selective effector of the radiation therapy response in androgen receptor-positive prostate cancer

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Targeting the autophagy pathway using ectopic expression of Beclin 1 in combination with rapamycin in drug-resistant v-Ha-ras-transformed NIH 3T3 cells

30 September 2017

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Altered expression of signaling genes in Jurkat cells upon FTY720 induced apoptosis

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Integrated preclinical and clinical development of mTOR inhibitors in pancreatic cancer.

30 September 2017

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Targeting epidermal growth factor receptor-associated signaling pathways in non-small cell lung cancer cells: implication in radiation response

30 September 2017

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Enhanced radiosensitivity of EC109 cells by inhibition of HDAC1 expression

30 September 2017

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30 September 2017

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Stage 2 combination testing of rapamycin with cytotoxic agents by the Pediatric Preclinical Testing Program

30 September 2017

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Targeting HER2 signaling pathway for radiosensitization: alternative strategy for therapeutic resistance

30 September 2017

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Rapamycin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and induction of apoptosis

30 September 2017

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Antiproliferative and overadditive effects of rapamycin and FTY720 in pancreatic cancer cells in vitro

30 September 2017

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Rapamycin delays growth of Wnt-1 tumors in spite of suppression of host immunity

30 September 2017

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Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer

30 September 2017

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RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model

30 September 2017

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Recruitment of DNA repair synthesis machinery to sites of DNA damage/repair in living human cells

30 September 2017

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Mammalian target of rapamycin is a promising target for novel therapeutic strategy against cancer.

30 September 2017

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Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells

30 September 2017

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Down-regulation of survivin expression by small interfering RNA induces pancreatic cancer cell apoptosis and enhances its radiosensitivity

30 September 2017

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Radiation and new molecular agents part I: targeting ATM-ATR checkpoints, DNA repair, and the proteasome

30 September 2017

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Double-strand breaks: signaling pathways and repair mechanisms.

30 September 2017

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30 September 2017

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Role of cell cycle in mediating sensitivity to radiotherapy

30 September 2017

1 reference

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Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

Contribution of base lesions to radiation-induced clustered DNA damage: implication for models of radiation response

30 September 2017

1 reference

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Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

30 September 2017

1 reference

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Induction and repair of chromosome aberrations in scid cells measured by premature chromosome condensation.

30 September 2017

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Rapamycin enhances docetaxel-induced cytotoxicity in a androgen-independent prostate cancer xenograft model by survivin downregulation

30 September 2017

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Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model

28 June 2018

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Analysis of gene transcription in cells lacking DNA-PK activity.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

Targeted inhibition of mammalian target of rapamycin (mTOR) signaling pathway inhibits proliferation and induces apoptosis of laryngeal carcinoma cells in vitro.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

Autophagy, senescence and tumor dormancy in cancer therapy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

Monitoring antitumor efficacy of rapamycin in Kaposi sarcoma

5 September 2018

1 reference

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DNA damage responses in cell cycle G2 phase and mitosis--tracking and targeting.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

Rapamycin inhibits proliferation and differentiation of human endothelial progenitor cells in vitro

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610438

Changes in expression of p53, proliferating cell nuclear antigen and bcl-2 in recurrent laryngeal cancer after radiotherapy

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23662044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2147/DDDT.S42390

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

23662044

1 reference