Treatment of childhood Plasmodium falciparum malaria: current challenges (Q36723819)

15 August 2017

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title

Treatment of childhood Plasmodium falciparum malaria: current challenges (English)

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Plasmodium falciparum malaria

15 August 2017

Plasmodium falciparum

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malaria

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2

Malcolm E Molyneux

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15 August 2017

David J Bell

1

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15 August 2017

1 February 2007

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Expert Review of Anti-infective Therapy

15 August 2017

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15 August 2017

5

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15 August 2017

1

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15 August 2017

141-152

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Focus on Plasmodium vivax

15 August 2017

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Age-dependent characteristics of protection v. susceptibility to Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Rapid diagnostic testing for malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Cerebral malaria is frequently associated with latent parasitemia among the semi-immune population of eastern Sudan

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Incidence and management of malaria in two communities of different socio-economic level, in Accra, Ghana

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Overdiagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Chloroquine-resistant malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Sustained clinical efficacy of sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Malawi after 10 years as first line treatment: five year prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Cardiac effects of halofantrine in children suffering from acute uncomplicated falciparum malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Detection of antidrug IgG antibodies in patients with adverse drug reactions to amodiaquine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Poor efficacy of antimalarial biguanide-dapsone combinations in the treatment of acute, uncomplicated, falciparum malaria in Thailand

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Effects of artemisinin derivatives on malaria transmissibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Estimates of the infectious reservoir of Plasmodium falciparum malaria in The Gambia and in Tanzania

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem).

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Amodiaquine alone, amodiaquine+sulfadoxine-pyrimethamine, amodiaquine+artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Supervised versus unsupervised intake of six-dose artemether-lumefantrine for treatment of acute, uncomplicated Plasmodium falciparum malaria in Mbarara, Uganda: a randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Safety and efficacy of dihydroartemisinin/piperaquine (Artekin) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan children

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Amodiaquine combined with sulfadoxine/pyrimethamine versus artemisinin-based combinations for the treatment of uncomplicated falciparum malaria in Africa: a meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Manslaughter by fake artesunate in Asia--will Africa be next?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Sulfadoxine-pyrimethamine pharmacokinetics in malaria: pediatric dosing implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzanian infants: a randomised, placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Intermittent preventive antimalarial treatment for Tanzanian infants: follow-up to age 2 years of a randomised, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

A comparison of case-control and family-based association methods: the example of sickle-cell and malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Alpha(+)-thalassemia protects African children from severe malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Haemoglobinopathies and resistance to malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

How malaria has affected the human genome and what human genetics can teach us about malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Effects of HIV-1 serostatus, HIV-1 RNA concentration, and CD4 cell count on the incidence of malaria infection in a cohort of adults in rural Malawi

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Increasing rates of malarial fever with deteriorating immune status in HIV-1-infected Ugandan adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

HIV infection as a cofactor for severe falciparum malaria in adults living in a region of unstable malaria transmission in South Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Genetic analysis of circulating and sequestered populations of Plasmodium falciparum in fatal pediatric malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Virulence of malaria is associated with differential expression of Plasmodium falciparum var gene subgroups in a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Indicators of life-threatening malaria in African children

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Blood glucose levels in Malawian children before and during the administration of intravenous quinine for severe falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

The effect ofPlasmodium falciparumon cognition: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Seizures and status epilepticus in childhood cerebral malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Effect of phenobarbital on seizure frequency and mortality in childhood cerebral malaria: a randomised, controlled intervention study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Severe P. falciparum malaria in Kenyan children: evidence for hypovolaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Randomized trial of volume expansion with albumin or saline in children with severe malaria: preliminary evidence of albumin benefit

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Volume expansion with albumin compared to gelofusine in children with severe malaria: results of a controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Hemofiltration and peritoneal dialysis in infection-associated acute renal failure in Vietnam

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Bacteremia among children admitted to a rural hospital in Kenya.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Clinical presentation of non-typhoidal Salmonella bacteraemia in Malawian children

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

A meta-analysis using individual patient data of trials comparing artemether with quinine in the treatment of severe falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Safety and efficacy of rectal compared with intramuscular quinine for the early treatment of moderately severe malaria in children: randomised clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Efficacy of rectal artesunate compared with parenteral quinine in initial treatment of moderately severe malaria in African children and adults: a randomised study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Artesunate suppositories versus intramuscular artemether for treatment of severe malaria in children in Papua New Guinea

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Rectal artemether versus intravenous quinine for the treatment of cerebral malaria in children in Uganda: randomised clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Dose-dependent resorption of quinine after intrarectal administration to children with moderate Plasmodium falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Efficacy and safety of intranasal lorazepam versus intramuscular paraldehyde for protracted convulsions in children: an open randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.141

21 January 2018

Identifiers

DOI

10.1586/14787210.5.1.141

1 reference

15 August 2017

1 reference

PubMed ID

17266461