The promoter of the human interleukin-2 gene contains two octamer-binding sites and is partially activated by the expression of Oct-2. (Q36729328)

15 August 2017

The promoter of the human interleukin-2 gene contains two octamer-binding sites and is partially activated by the expression of Oct-2. (English)

1 reference

15 August 2017

M P Kamps

1

1 reference

15 August 2017

L Corcoran

series ordinal

2

1 reference

15 August 2017

J H LeBowitz

series ordinal

3

1 reference

15 August 2017

D Baltimore

series ordinal

4

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 October 1990

1 reference

Molecular and Cellular Biology

15 August 2017

1 reference

15 August 2017

10

1 reference

15 August 2017

10

1 reference

15 August 2017

5464-5472

1 reference

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Two regulatory elements for immunoglobulin kappa light chain gene expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Structure of the human interleukin 2 gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

57 Sequencing end-labeled DNA with base-specific chemical cleavages

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Cloning of a Lymphoid-Specific cDNA Encoding a Protein Binding the Regulatory Octamer DNA Motif

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Identification of a putative regulator of early T cell activation genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Characterization of antigen receptor response elements within the interleukin-2 enhancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic clipping bandshift assay (PCBA).

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Cell-type preference of immunoglobulin kappa and lambda gene promoters

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Identification of multiple cis-elements and trans-acting factors involved in the induced expression of human IL-2 gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Ubiquitous and lymphocyte-specific factors are involved in the induction of the mouse interleukin 2 gene in T lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Complexity of the primary genetic response to mitogenic activation of human T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Transcription signals in embryonic Xenopus laevis U1 RNA genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Transcription of a gene for human U1 small nuclear RNA.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Activation of a human T cell line: a two-stimulus requirement in the pretranslational events involved in the coordinate expression of interleukin 2 and gamma-interferon genes.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

Regulation of human interleukin-2 gene: functional DNA sequences in the 5' flanking region for the gene expression in activated T lymphocytes.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361254

The Oct-2 protein binds cooperatively to adjacent octamer sites

28 June 2018

1 reference

12 December 2020

Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2

1 reference

12 December 2020

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

1 reference

12 December 2020

The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level

1 reference

12 December 2020

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1 reference

12 December 2020

The antigen receptor on a human T cell line initiates activation by increasing cytoplasmic free calcium

1 reference

12 December 2020

An immunoglobulin promoter displays cell-type specificity independently of the enhancer

1 reference

12 December 2020

An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes

1 reference

12 December 2020

Antigen-specific T cell activation results in an increase in cytoplasmic free calcium

1 reference

12 December 2020

Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility

1 reference

12 December 2020

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1 reference

12 December 2020

IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells

1 reference

12 December 2020

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

1 reference

12 December 2020

Absolute requirement for adherent cells in the production of human interleukin 2 (IL2)

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.10.10.5464

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

2204815

1 reference