DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX. (Q36732878)

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scientific article published on July 2004

Language	Label	Description	Also known as
English	DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX.	scientific article published on July 2004

Statements

scholarly article

1 reference

Europe PubMed Central

16 August 2017

DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX. (English)

1 reference

Europe PubMed Central

16 August 2017

0 references

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author name string

Milota Kaluzová

1

1 reference

Europe PubMed Central

16 August 2017

Stefan Kaluz

2

1 reference

Europe PubMed Central

16 August 2017

Michael I Lerman

3

1 reference

Europe PubMed Central

16 August 2017

Eric J Stanbridge

4

1 reference

Europe PubMed Central

16 August 2017

language of work or name

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publication date

1 July 2004

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Europe PubMed Central

16 August 2017

Molecular and Cellular Biology

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Europe PubMed Central

16 August 2017

24

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Europe PubMed Central

16 August 2017

13

1 reference

Europe PubMed Central

16 August 2017

5757-5766

1 reference

Europe PubMed Central

16 August 2017

The histological structure of some human lung cancers and the possible implications for radiotherapy

1 reference

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30 September 2017

Targeting HIF-1 for cancer therapy

1 reference

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Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor

1 reference

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Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function

1 reference

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Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy

1 reference

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GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: relationship to pimonidazole binding.

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Catalase protects HepG2 cells from apoptosis induced by DNA-damaging agents by accelerating the degradation of p53.

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Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1 alpha stabilization: a role for phosphatidylinositol 3'-kinase

1 reference

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Hypoxia--a key regulatory factor in tumour growth

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Hypoxia links ATR and p53 through replication arrest

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Cell density mediated pericellular hypoxia leads to induction of HIF-1alpha via nitric oxide and Ras/MAP kinase mediated signaling pathways

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer.

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Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.

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Hypoxia-inducible expression of tumor-associated carbonic anhydrases

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Surfing the p53 network

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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Regulation of p53 stability by Mdm2

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An essential role for p300/CBP in the cellular response to hypoxia

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p53 mutations in human cancers

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Oncogenic forms of p53 inhibit p53-regulated gene expression

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P53 tumour suppressor modulates transcription of the TATA-less gene coding for the tumour-associated carbonic anhydrase MN/CA IX in MaTu cells.

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Hypoxia attenuates the p53 response to cellular damage

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1 reference

https://pubmed.ncbi.nlm.nih.gov/15199132

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based on heuristic

inferred from PubMed ID database lookup

p53 inhibits hypoxia-inducible factor-stimulated transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of the MN/CA 9 gene coding for the tumor-associated carbonic anhydrase IX. Identification and characterization of a proximal silencer element

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199132

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Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression

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https://pubmed.ncbi.nlm.nih.gov/15199132

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Mycoplasma detection-an obligation to scientific accuracy

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Identifiers

10.1128/MCB.24.13.5757-5766.2004

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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