A small-molecule E2F inhibitor blocks growth in a melanoma culture model (Q36737122)

16 August 2017

A small-molecule E2F inhibitor blocks growth in a melanoma culture model (English)

1 reference

16 August 2017

Yihong Ma

1

1 reference

16 August 2017

Courtney A Kurtyka

2

1 reference

16 August 2017

Sandhya Boyapalle

3

1 reference

16 August 2017

Shen-Shu Sung

4

1 reference

16 August 2017

Harshani Lawrence

5

1 reference

16 August 2017

Wayne Guida

6

1 reference

16 August 2017

W Douglas Cress

7

1 reference

16 August 2017

language of work or name

English

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publication date

1 August 2008

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16 August 2017

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16 August 2017

68

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16 August 2017

15

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16 August 2017

6292-6299

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describes a project that uses

16 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3615411/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

A review of the S100 proteins in cancer

1 reference

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Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Transcriptional upregulation of p57 (Kip2) by the cyclin-dependent kinase inhibitor BMS-387032 is E2F dependent and serves as a negative feedback loop limiting cytotoxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Putting the Oncogenic and Tumor Suppressive Activities of E2F into Context

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

E2F4 regulates a stable G2 arrest response to genotoxic stress in prostate carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Opposing roles of E2Fs in cell proliferation and death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Genotoxic stress induces expression of E2F4, leading to its association with p130 in prostate carcinoma cells.

29 September 2017

1 reference

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Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

29 September 2017

1 reference

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Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Inhibition of cell proliferation and induction of apoptosis by novel tetravalent peptides inhibiting DNA binding of E2F.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

The yin and yang of E2F-1: balancing life and death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Regulation of the cyclin D3 promoter by E2F1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Flavopiridol-induced apoptosis is mediated through up-regulation of E2F1 and repression of Mcl-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Direct repression of the Mcl-1 promoter by E2F1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Sibling rivalry in the E2F family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Identification of E2F-3B, an alternative form of E2F-3 lacking a conserved N-terminal region

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Rb function in cell-cycle regulation and apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that functionally antagonize E2F activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

E2F activity is regulated by cell cycle-dependent changes in subcellular localization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Conditional binding to and cell cycle-regulated inhibition of cyclin-dependent kinase complexes by p27Kip1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Differences in DNA binding properties between E2F1 and E2F4 specify repression of the Mcl-1 promoter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Hope in sight for retinoblastoma

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Compensation and specificity of function within the E2F family.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

E2F4 deficiency promotes drug-induced apoptosis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615411

Retinoblastoma protein inhibits IFN-gamma induced apoptosis

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18676853

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Apoptosis induced in mammalian cells by small peptides that functionally antagonize the Rb-regulated E2F transcription factor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18676853

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-08-0121

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

18676853

1 reference