Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite (Q36740177)

16 August 2017

Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite (English)

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16 August 2017

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Lucía Piacenza

1

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16 August 2017

Gonzalo Peluffo

2

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16 August 2017

María Noel Alvarez

3

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16 August 2017

John M Kelly

4

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16 August 2017

Shane R Wilkinson

5

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16 August 2017

Rafael Radi

6

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16 August 2017

language of work or name

English

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publication date

1 March 2008

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16 August 2017

10

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inferred from page(s)

published in

Biochemical Journal

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16 August 2017

410

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16 August 2017

2

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16 August 2017

359-368

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on focus list of Wikimedia project

16 August 2017

ScienceSource

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cites work

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29 September 2017

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Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence

29 September 2017

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Regeneration of peroxiredoxins during recovery after oxidative stress: only some overoxidized peroxiredoxins can be reduced during recovery after oxidative stress

29 September 2017

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RNA interference identifies two hydroperoxide metabolizing enzymes that are essential to the bloodstream form of the african trypanosome.

29 September 2017

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Peroxynitrite reactions and formation in mitochondria

29 September 2017

1 reference

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Cell signalling and Trypanosoma cruzi invasion

29 September 2017

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Don't bother to knock--the cell invasion strategy of Trypanosoma cruzi

29 September 2017

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Trypanosoma cruzi expresses a plant-like ascorbate-dependent hemoperoxidase localized to the endoplasmic reticulum

29 September 2017

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Immunological identification of the heart myoglobin radical formed by hydrogen peroxide

29 September 2017

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TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum

29 September 2017

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The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin.

29 September 2017

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L-arginine-dependent suppression of apoptosis in Trypanosoma cruzi: contribution of the nitric oxide and polyamine pathways

29 September 2017

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Unraveling peroxynitrite formation in biological systems.

29 September 2017

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Peroxynitrite reductase activity of bacterial peroxiredoxins

29 September 2017

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Distinct mitochondrial and cytosolic enzymes mediate trypanothione-dependent peroxide metabolism in Trypanosoma cruzi

29 September 2017

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Nitric oxide and peroxynitrite-dependent aconitase inactivation and iron-regulatory protein-1 activation in mammalian fibroblasts

29 September 2017

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The cysteine-cysteine family of chemokines RANTES, MIP-1alpha, and MIP-1beta induce trypanocidal activity in human macrophages via nitric oxide

29 September 2017

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Purification and characterization of trypanothione reductase from Crithidia fasciculata, a newly discovered member of the family of disulfide-containing flavoprotein reductases

29 September 2017

1 reference

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Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression

29 September 2017

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Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

28 June 2018

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Cell-substrate adhesion during Trypanosoma cruzi differentiation

28 June 2018

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Tyrosine nitration by superoxide and nitric oxide fluxes in biological systems: modeling the impact of superoxide dismutase and nitric oxide diffusion

28 June 2018

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The Trypanosoma cruzi proteome.

5 September 2018

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Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441817

Trypanosoma cruzi response to the oxidative stress generated by hydrogen peroxide.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441817

Reaction of human hemoglobin with peroxynitrite. Isomerization to nitrate and secondary formation of protein radicals

5 September 2018

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The trypanothione-thiol system in Trypanosoma cruzi as a key antioxidant mechanism against peroxynitrite-mediated cytotoxicity

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441817

Role of peroxidoxins in Leishmania chagasi survival. Evidence of an enzymatic defense against nitrosative stress

5 September 2018

1 reference

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Trypanothione-dependent peroxide metabolism in Trypanosoma cruzi different stages.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441817

Bactericidal potency of hydroxyl radical in physiological environments.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441817

Trypanosoma cruzi infection and the rat central nervous system: proliferation of parasites in astrocytes and the brain reaction to parasitism

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441817

The regulation of mitochondrial oxygen uptake by redox reactions involving nitric oxide and ubiquinol

4 December 2018

1 reference

12 December 2020

Peroxynitrite formation from biochemical and cellular fluxes of nitric oxide and superoxide

1 reference

12 December 2020

Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide

1 reference

12 December 2020

The contribution of vascular endothelial xanthine dehydrogenase/oxidase to oxygen-mediated cell injury

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12 December 2020

Activation of human macrophages for the killing of intracellular Trypanosoma cruzi by TNF-α and IFN-γ through a nitric oxide-dependent mechanism

1 reference

12 December 2020

Peroxynitrite-mediated cytotoxicity to Trypanosoma cruzi

1 reference

12 December 2020

Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondrial particles

1 reference

12 December 2020

Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20071138

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16 August 2017

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16 August 2017

PubMed publication ID

17973627

1 reference